Recurrent, severe wheezing is associated with morbidity and mortality in adults with sickle cell disease

American Journal of Hematology

Volumn 86, Issue 9, 2011, Pages 756-761

  Cohen, Robyn T ^a   Madadi, Anusha ^b   Blinder, Morey A ^c   Debaun, Michael R ^d   Strunk, Robert C ^c   Field, Joshua J ^e,f  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b ST LUKE S HOSPITAL   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d VANDERBILT UNIVERSITY   (United States)

^e BLOOD RESEARCH INSTITUTE   (United States)

^f MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN E;

ACUTE CHEST SYNDROME; ADULT; ADULT DISEASE; AGED; ARTICLE; ASTHMA; CLINICAL FEATURE; COMPARATIVE STUDY; DISEASE SEVERITY; ECZEMA; FAMILY HISTORY; FEMALE; FOLLOW UP; HOSPITALIZATION; HUMAN; LUNG FUNCTION TEST; MAJOR CLINICAL STUDY; MALE; MORBIDITY; MORTALITY; OBSERVATIONAL STUDY; PAIN; PRIORITY JOURNAL; QUESTIONNAIRE; RECURRENT DISEASE; SICKLE CELL ANEMIA; SURVIVAL; WHEEZING;

ACUTE CHEST SYNDROME; ADOLESCENT; ADULT; AGED; ANEMIA, SICKLE CELL; ASTHMA; BIOLOGICAL MARKERS; COHORT STUDIES; FEMALE; HUMANS; IMMUNOGLOBULIN E; MALE; MIDDLE AGED; MORBIDITY; PAIN MEASUREMENT; PROSPECTIVE STUDIES; QUESTIONNAIRES; RESPIRATORY SOUNDS; SURVIVAL ANALYSIS; UNITED STATES; YOUNG ADULT;

EID: 80051785110     PISSN: 03618609     EISSN: 10968652     Source Type: Journal    
DOI: 10.1002/ajh.22098     Document Type: Article

References (52)

1. Ross J, Bernaudin F, Strunk RC, et al. Asthma is a distinct co-morbid condition in children with sickle cell anemia with elevated total and allergen-specific IgE levels. J Pediatr Hematol Oncol 2011;33:e205-e208.
2. Boyd JH, Macklin EA, Strunk RC, et al. Asthma is associated with acute chest syndrome and pain in children with sickle cell anemia. Blood 2006; 108: 2923-2927.
3. Boyd JH, Moinuddin A, Strunk RC, et al. Asthma and acute chest in sickle-cell disease. Pediatr Pulmonol 2004; 38: 229-232.
4. Glassberg J, Spivey JF, Strunk R, et al. Painful episodes in children with sickle cell disease and asthma are temporally associated with respiratory symptoms. J Pediatr Hematol Oncol 2006; 28: 481-485.
5. Vichinsky EP, Styles LA, Colangelo LH, et al. Acute chest syndrome in sickle cell disease: Clinical presentation and course. Cooperative Study of Sickle Cell Disease. Blood 1997; 89: 1787-1792.
6. Dean D, Neumayr L, Kelly DM, et al. Chlamydia pneumoniae and acute chest syndrome in patients with sickle cell disease. J Pediatr Hematol Oncol 2003; 25: 46-55.
7. Neumayr L, Lennette E, Kelly D, et al. Mycoplasma disease and acute chest syndrome in sickle cell disease. Pediatrics 2003; 112(Part 1): 87-95.
8. Ferris BG. Epidemiology Standardization Project (American Thoracic Society). Am Rev Respir Dis 1978; 118(Part 2): 1-120.
9. Shilo NR, Lands LC. Asthma and chronic sickle cell lung disease: A dynamic relationship. Paediatr Respir Rev 2011; 12: 78-82.
10. Vichinsky EP, Neumayr LD, Earles AN, et al. Causes and outcomes of the acute chest syndrome in sickle cell disease. National Acute Chest Syndrome Study Group. N Engl J Med 2000; 342: 1855-1865.
11. Field JJ, Krings J, White NL, et al. Urinary cysteinyl leukotriene E(4) is associated with increased risk for pain and acute chest syndrome in adults with sickle cell disease. Am J Hematol 2009; 84: 158-160.
12. Miller MR, Hankinson J, Brusasco V, et al. Standardisation of spirometry. Eur Respir J 2005; 26: 319-338.
13. Hankinson JL, Odencrantz JR, Fedan KB. Spirometric reference values from a sample of the general U.S. population. Am J Respir Crit Care Med 1999; 159: 179-187.
14. Platt OS, Thorington BD, Brambilla DJ, et al. Pain in sickle cell disease. Rates and risk factors. N Engl J Med 1991; 325: 11-16.
15. Cohen RT, DeBaun MR, Blinder MA, et al. Smoking is associated with an increased risk of acute chest syndrome and pain among adults with sickle cell disease. Blood 2010; 115: 3852-3854.
16. Castro O, Brambilla DJ, Thorington B, et al. The acute chest syndrome in sickle cell disease: Incidence and risk factors. The Cooperative Study of Sickle Cell Disease. Blood 1994; 84: 643-649.
17. Platt OS, Brambilla DJ, Rosse WF, et al. Mortality in sickle cell disease. Life expectancy and risk factors for early death. N Engl J Med 1994; 330: 1639-1644.
18. Boyd JH, Macklin EA, Strunk RC, et al. Asthma is associated with increased mortality in individuals with sickle cell anemia. Haematologica 2007; 92: 1115-1118.
19. Kato GJ, McGowan V, Machado RF, et al. Lactate dehydrogenase as a biomarker of hemolysis-associated nitric oxide resistance, priapism, leg ulceration, pulmonary hypertension, and death in patients with sickle cell disease. Blood 2006; 107: 2279-2285.
20. Burrows B, Martinez FD, Halonen M, et al. Association of asthma with serum IgE levels and skin-test reactivity to allergens. N Engl J Med 1989; 320: 271-277.
21. Lange P, Parner J, Vestbo J, et al. A 15-year follow-up study of ventilatory function in adults with asthma. N Engl J Med 1998; 339: 1194-1200.
22. Bousquet J, Chanez P, Lacoste JY, et al. Eosinophilic inflammation in asthma. N Engl J Med 1990; 323: 1033-1039.
23. Wilson NM, Dore CJ, Silverman M. Factors relating to the severity of symptoms at 5 yrs in children with severe wheeze in the first 2 yrs of life. Eur Respir J 1997; 10: 346-353.
24. Young S, Le Souef PN, Geelhoed GC, et al. The influence of a family history of asthma and parental smoking on airway responsiveness in early infancy. N Engl J Med 1991; 324: 1168-1173.
25. An P, Barron-Casella EA, Strunk RC, et al. Elevation of IgE in children with sickle cell disease is associated with doctor diagnosis of asthma and increased morbidity. J Allergy Clin Immunol 2011;127:1440-1446.
26. Ozbek OY, Malbora B, Sen N, et al. Airway hyperreactivity detected by methacholine challenge in children with sickle cell disease. Pediatr Pulmonol 2007; 42: 1187-1192.
27. Klings ES, Wyszynski DF, Nolan VG, et al. Abnormal pulmonary function in adults with sickle cell anemia. Am J Respir Crit Care Med 2006; 173: 1264-1269.
28. Arif AA, Delclos GL, Lee ES, et al. Prevalence and risk factors of asthma and wheezing among US adults: An analysis of the NHANES III data. Eur Respir J 2003; 21: 827-833.
29. Moorman JE, Rudd RA, Johnson CA, et al. National surveillance for asthma-United States, 1980-2004. MMWR Surveill Summ 2007; 56: 1-54.
30. Delclaux C, Zerah-Lancner F, Bachir D, et al. Factors associated with dyspnea in adult patients with sickle cell disease. Chest 2005; 128: 3336-3344.
31. Miller GJ, Serjeant GR. An assessment of lung volumes and gas transfer in sickle-cell anaemia. Thorax 1971; 26: 309-315.
32. Bush A, Menzies-Gow A. Phenotypic differences between pediatric and adult asthma. Proc Am Thorac Soc 2009; 6: 712-719.
33. Chaudhuri R, Livingston E, McMahon AD, et al. Cigarette smoking impairs the therapeutic response to oral corticosteroids in chronic asthma. Am J Respir Crit Care Med 2003; 168: 1308-1311.
34. Court CS, Cook DG, Strachan DP. Comparative epidemiology of atopic and non-atopic wheeze and diagnosed asthma in a national sample of English adults. Thorax 2002; 57: 951-957.
35. Chronic obstructive pulmonary disease guidelines. British Thoracic Society 2010.
36. Vercelli D. Arginase: Marker, effector, or candidate gene for asthma? J Clin Invest 2003; 111: 1815-1817.
37. Zimmermann N, King NE, Laporte J, et al. Dissection of experimental asthma with DNA microarray analysis identifies arginase in asthma pathogenesis. J Clin Invest 2003; 111: 1863-1874.
38. Fischer A, Folkerts G, Geppetti P, et al. Mediators of asthma: Nitric oxide. Pulm Pharmacol Ther 2002; 15: 73-81.
39. Field JJ, Stocks J, Kirkham FJ, et al. Airway hyperresponsiveness in children with sickle cell anemia. Chest 2011; 139: 563-568.
40. Phelan PD, Robertson CF, Olinsky A. The Melbourne Asthma Study: 1964-1999. J Allergy Clin Immunol 2002; 109: 189-194.
41. Zeiger RS, Dawson C, Weiss S. Relationships between duration of asthma and asthma severity among children in the Childhood Asthma Management Program (CAMP). J Allergy Clin Immunol 1999; 103(Part 1): 376-387.
42. Vonk JM, Postma DS, Boezen HM, et al. Childhood factors associated with asthma remission after 30 year follow up. Thorax 2004; 59: 925-929.
43. NAEPP guidelines. Amercian Academy of Allergy Asthma and Immunology 2009.
44. Bernini JC, Rogers ZR, Sandler ES, et al. Beneficial effect of intravenous dexamethasone in children with mild to moderately severe acute chest syndrome complicating sickle cell disease. Blood 1998; 92: 3082-3089.
45. Strouse JJ, Takemoto CM, Keefer JR, et al. Corticosteroids and increased risk of readmission after acute chest syndrome in children with sickle cell disease. Pediatr Blood Cancer 2008; 50: 1006-1012.
46. Darbari DS, Castro O, Taylor JGT, et al. Severe vaso-occlusive episodes associated with use of systemic corticosteroids in patients with sickle cell disease. J Natl Med Assoc 2008; 100: 948-951.
47. Sobota A, Graham DA, Heeney MM, et al. Corticosteroids for acute chest syndrome in children with sickle cell disease: Variation in use and association with length of stay and readmission. Am J Hematol 2010; 85: 24-28.
48. Toren K, Brisman J, Jarvholm B. Asthma and asthma-like symptoms in adults assessed by questionnaires. A literature review. Chest 1993; 104: 600-608.
49. Enright PL, Kronmal RA, Higgins MW, et al. Prevalence and correlates of respiratory symptoms and disease in the elderly. Cardiovascular Health Study. Chest 1994; 106: 827-834.
50. Childhood Asthma Management Program (CAMP) Reserach Group. Reserach Group, Design, Rationale, and Methods. Clin Trial 1999; 20: 91-120.
51. Powars D, Weidman JA, Odom-Maryon T, et al. Sickle cell chronic lung disease: Prior morbidity and the risk of pulmonary failure. Medicine (Baltimore) 1988; 67: 66-76.
52. Gladwin MT, Sachdev V, Jison ML, et al. Pulmonary hypertension as a risk factor for death in patients with sickle cell disease. N Engl J Med 2004; 350: 886-895.