Spinal cord stimulation and cerebral hemodynamics: Updated mechanism and therapeutic implications

Stereotactic and Functional Neurosurgery

Volumn 89, Issue 5, 2011, Pages 263-274

  Visocchi, Massimiliano ^a   Della Pepa, Giuseppe Maria ^a   Esposito, Giuseppe ^a   Tufo, Tommaso ^a   Zhang, Wenchuan ^b   Li, Shiting ^b   Zhong, Jun ^b  

^a CATHOLIC UNIVERSITY   (Italy)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Brain injury; Cerebral autoregulation; Cerebral blood flow; Functional sympathectomy; Spinal cord stimulation; Stroke; Vasospasm

Indexed keywords

HUMORAL ANTIBODY;

AUTONOMIC NERVOUS SYSTEM; AUTOREGULATION; BRAIN BLOOD FLOW; BRAIN ISCHEMIA; BRAIN PERFUSION; BRAIN PROTECTION; CEREBROVASCULAR DISEASE; ELECTRODE; HUMAN; INTRACTABLE PAIN; NEUROSURGERY; NONHUMAN; OBSERVATIONAL STUDY; REVIEW; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SPINAL CORD STIMULATION; SUBARACHNOID HEMORRHAGE; TRAUMATIC ISCHEMIC BRAIN DAMAGE; VASOSPASM;

ANIMALS; BRAIN; CEREBROVASCULAR CIRCULATION; CEREBROVASCULAR DISORDERS; CLINICAL TRIALS AS TOPIC; ELECTRIC STIMULATION THERAPY; HEMODYNAMICS; HUMANS; SPINAL CORD;

EID: 80051784621     PISSN: 10116125     EISSN: 14230372     Source Type: Journal    
DOI: 10.1159/000329357     Document Type: Review

References (65)

1. Visocchi M: Spinal cord stimulation and cerebral haemodynamics. Acta Neurochir Suppl 2006; 99: 111-116.
2. De Vries J, De Jongste MJ, Spincemaille G, Staal MJ: Spinal cord stimulation for ischemic heart disease and peripheral vascular disease. Adv Tech Stand Neurosurg 2007; 32: 63-89.
3. Augustinsson LE, Eliasson T, Mannheimer C: Spinal cord stimulation in severe angina pectoris. Stereotact Funct Neurosurg 1995; 65: 136-141. (Pubitemid 26344513)
4. Goellner E, Slavin KV: Cervical spinal cord stimulation may prevent cerebral vasospasm by modulating sympathetic activity of the superior cervical ganglion at lower cervical spinal level. Med Hypotheses 2009;73: 410-413.
5. Robaina F, Clavo B: Spinal cord stimulation in the treatment of post-stroke patients: Current state and future directions. Acta Neurochir Suppl 2007; 97: 277-282.
6. Reis DJ: Central Neural Control of Cerebral Circulation and Metabolism. New York, Raven Press, 1984, vol 2, pp 91-119.
7. Garcia-March G, Sanchez-Ledesna MJ, Broseta J: Effect of high cervical spinal cord stimulation on carotid and cerebral blood flow. An experimental study. Proc 8th European Congress of Neurosurgery, Barcelona 1987, p 106.
8. Visocchi M, Cioni B, Vergari S, Marano G, Pentimalli L, Meglio M: Spinal cord stimulation and cerebral blood flow: An experimental study. Stereotact Funct Neurosurg 1994; 62: 186-190.
9. Garcia-March G, Sánchez-Ledesma MJ, Anaya J, Broseta J: Cerebral and carotid haemodynamic changes following cervical spinal cord stimulation. An experimental study. Acta Neurochir Suppl (Wien) 1989; 46: 102-104.
10. Isono M, Kaga A, Fujiki M, Mori T, Hori S: Effect of spinal cord stimulation on cerebral blood flow in cats. Stereotact Funct Neurosurg 1995; 64: 40-46.
11. Sagher O, Huang DL: Effects of the cervical spinal cord stimulation on cerebral blood flow in the rat. J Neurosurg 2000; 93: 71-76. (Pubitemid 30457385)
12. Zhong J, Huang DL, Sagher O: Parameters influencing augmentation of cerebral blood flow by cervical spinal cord stimulation. Acta Neurochir (Wien) 2004; 146: 1227-1234. (Pubitemid 39517794)
13. Hosobuchi Y: Electrical stimulation of the cervical spinal cord increases cerebral blood flow in humans. Appl Neurophysiol 1985; 48: 372-376. (Pubitemid 16064626)
14. Aaslid R, Markwalder TM, Nornes H: Noninvasive transcranial Doppler ultrasound recording of flow velocity in basal cerebral arteries. J Neurosurg 1982; 57: 769-774. (Pubitemid 13208286)
15. Linderoth B, Gherardini G, Ren BB, Lundeberg T: Preemptive spinal cord stimulation reduces ischemia in an animal model of vasospasm. Neurosurgery 1995; 37: 266-271.
16. Linderoth B, Gunasekera L, Meyerson BA: Effects of sympathectomy on skin and muscle microcirculation during dorsal column stimulation. Neurosurgery 1991; 29: 874-879.
17. Meglio M, Cioni B, Visocchi M: Cerebral haemodynamics during spinal cord stimulation. PACE 1991; 14: 127-130.
18. Meglio M, Cioni B, Visocchi M, Nobili F, Rodriguez G, Rosadini G, Chiappini F, Sandric S: Spinal cord stimulation and cerebral haemodynamics. Acta Neurochir (Wien) 1991; 111: 43-48.
19. Mazzone P, Pisani R, Nobili F, Arrigo A, Rosadini G: Assessment of regional cerebral blood flow during spinal cord stimulation in humans. Stereotact Funct Neurosurg 1995; 64: 197-201. (Pubitemid 26201790)
20. Mazzone P, Rodriguez G, Arrigo A, Nobili F, Rosadini G: Cerebral haemodynamic changes induced by spinal cord stimulation in man. Ital J Neurol Sci 1996; 17: 55-57. (Pubitemid 126765653)
21. Ter Laan M, van Dijk JM, Elting JW, Fidler V, Staal MJ: The influence of transcutaneous electrical neurostimulation (TENS) on human cerebral blood flow velocities. Acta Neurochir (Wien) 2010; 152: 1367-1373.
22. Meglio M, Cioni B, Dal Lago A, De Santis M, Pola P, Serricchio M: Pain control and improvement of peripheral blood flow following epidural spinal cord stimulation. Case report. J Neurosurg 1981; 54: 821-823.
23. Meglio M, Cioni B, Rossi GF, Sandric S, Santarelli P: Spinal cord stimulation affects the central mechanisms of regulation of heart rate. Appl Neurophysiol 1986; 49: 139-146. (Pubitemid 17005466)
24. Visocchi M, Chiappini F, Cioni B, Meglio M: Cerebral blood flow velocities and trigeminal ganglion stimulation - A transcranial Doppler study. Stereotact Funct Neurosurg 1996;66:184-192.
25. Myklebust JB, Cusick JF, Boerboom LE, Prieto TE, Khan TA: Vascular effects of spinal cord stimulation in the monkey. Stereotact Funct Neurosurg 1995; 64: 32-39.
26. Patel S, Huang DL, Sagher O: Sympathetic mechanisms in cerebral blood flow alterations induced by spinal cord stimulation. J Neurosurg 2003; 99: 754-761. (Pubitemid 37159052)
27. Patel S, Huang DL, Sagher O: Evidence for a central pathway in the cerebrovascular effects of spinal cord stimulation. Neurosurgery 2004,55: 201-206. (Pubitemid 38859108)
28. Linderoth B, Gherardini G, Ren B, Lundeberg T: Severe peripheral ischemia after vasospasm may be prevented by spinal cord stimulation. A preliminary report of study in a free-flap animal model. Acta Neurochir Suppl 1995; 64: 101-105.
29. Wu M, Komori N, Qin C, Farber JP, Linderoth B, Foreman RD: Roles of peripheral terminals of transient receptor potential vanilloid- 1 containing sensory fibers in spinal cord stimulation-induced peripheral vasodilation. Brain Res 2007; 1156: 80-92. (Pubitemid 46920517)
30. Yang X, Farber JP, Wu M, Foreman RD, Qin C: Roles of dorsal column pathway and transient receptor potential vanilloid type 1 in augmentation of cerebral blood flow by upper cervical spinal cord stimulation in rats. Neuroscience 2008; 152: 950-958.
31. Wu M, Komori N, Qin C, Farber JP, Linderoth B, Foreman RD: Extracellular signalregulated kinase and protein kinase B pathways involved in spinal cord stimulation-induced vasodilation. Brain Res 2008; 1207: 73-83.
32. Visocchi M, Bucci MG, Cioni B, Manni G, Meglio M, Puca A, Quaranta L: Cerebral and ophthalmic haemodynamics during SCS. I International INS Congress Rome, 1992. Bologna, Monduzzi, 1992, pp 137-143.
33. Visocchi M, Cioni B, Meglio M: Spinal cord stimulation impairs cerebral autoregulation. Acta Med Rom 1996; 28: 173-178.
34. Matsui T, Hosobuchi Y: The effects of cervical spinal cord stimulation on experimental stroke. PACE 1989; 12: 726-732. (Pubitemid 19145925)
35. Gonzalez-Darder J, Canadas-Rodriguez D: Effects of cervical spinal cord stimulation in experimental ischemic oedema. Neurol Res 1991; 13: 229-232.
36. Broseta J, Garcia-Mark G, Sancez-Ledesma MJ, Goncalves J: High cervical spinal cord electrical stimulation in brain low-perfusion syndromes: Experimental basis and preliminary clinical report. Stereotact Funct Neurosurg 1994; 62: 171-178.
37. Sagher O, Huang DL, Keep RF: Spinal cord stimulation reducing infarct volume in a model of focal cerebral ischemia in rats. J Neurosurg 2003; 99: 131-137. (Pubitemid 36753887)
38. Visocchi M, Argiolas L, Meglio M, Cioni B, Dal Basso P, Rollo M, Cabezas Cuevas D: Spinal cord stimulation and early experimental cerebral spasm: The functional monitoring and the preventing effect. Acta Neurochir (Wien) 2001; 143: 177-185.
39. Treggiari MM, Romand JA, Martin JB, Reverdin A, Rüfenacht DA, de Tribolet N: Cervical sympathetic block to reverse delayed ischemic neurological deficits after aneurysmal subarachnoid hemorrhage. Stroke 2003; 34: 961-967.
40. Naredi S, Lambert G, Edén E, Zäll S, Runnerstam M, Rydenhag B, Friberg P: Increased sympathetic nervous activity in patients with nontraumatic subarachnoid hemorrhage. Stroke 2000; 31: 901-906. (Pubitemid 30198436)
41. Visocchi M: Neuromodulation of cerebral blood flow by spinal cord electrical stimulation: The role of the Italian school and state of art. J Neurosurg Sci 2008;52:41-47.
42. Visocchi M, Meglio M, Argiolas L, Pentimalli L, Cioni B: Spinal cord stimulation prevents cerebral early vasospasm. An experimental study. III INS Congress, Orlando, March 6-10, 1996, pp 56-57.
43. Visocchi M, Tartaglione T, Romani R, Meglio M: Spinal cord stimulation prevents the effects of combined ischemic and traumatic brain injury. An MR study. Stereotact Funct Neurosurg 2001; 76: 276-281. (Pubitemid 36151241)
44. Ebel H, Semmelmann G, Schomaker K, Balogh A, Volz M, Funke J, Schicha H, Klug N: Effects of high cervical SCS on regional CBF after induced SAH in rats. Acta Neurochir Suppl 2001; 77: 225-227.
45. Ebel H, Semmelmann G, Schomaker K, Balogh A, Volz M, Funke J, Schicha H, Klug N: High cervical SCS increases regional CBF after induced SAH in rats. Minim Invasive Neurosurg 2001; 44: 167-171.
46. Gurelik M, Kayabas M, Karadag O, Goksel HM, Akyuz A, Topaktas S: Cervical SCS improves neurological dysfunction induced by cerebral vasospasm. Neuroscience 2005; 134: 837-832.
47. Karadag O, Eroglu E, Gurelik M, Goksel HM, Kilic E, Gulturk S: Cervical SCS increases cerebral cortical BF in an experimental cerebral vasospasm model. Acta Neurochir (Wien) 2005; 147: 79-84.
48. Kanno T, Yoshifumi K, Yokoyama T, Shoda M, Tanji H, Nomura M: Effects of dorsal column spinal cord stimulation on reversibility of neuronal function. Experience of treatment for vegetative states. PACE 1989; 12: 733-742.
49. Matsui T, Asano T, Takakura K, Yamada R, Hosobuchi Y: Beneficial effects of cervical spinal cord stimulation on patients with impaired consciousness: A preliminary report: PACE 1989; 12: 718-725. (Pubitemid 19145924)
50. Hosobuchi Y: Treatment of cerebral ischemia with electrical stimulation of the cervical spinal cord. PACE 1991; 14: 122-126.
51. Visocchi M, Cioni B, Pentimalli L, Meglio M: Increase of cerebral blood flow and improvement of brain motor control following spinal cord stimulation in ischemic spastic hemiparesis. Stereotact Funct Neurosurg 1994; 62: 103-107.
52. Visocchi M, Giordano A, Calcagni M, Cioni B, Di Rocco C, Meglio M: Spinal cord stimulation and cerebral blood flow in stroke: Personal experience. Stereotact Funct Neurosurg 2001; 76: 262-268. (Pubitemid 36151239)
53. De Andrés J, Tatay J, Revert A, Valía JC, Villanueva V: The beneficial effect of spinal cord stimulation in a patient with severe cerebral ischemia and upper extremity ischemic pain. Pain Pract 2007; 7: 135-142. (Pubitemid 46901550)
54. Liu JT, Tan WC, Liao WJ: Effects of electrical cervical spinal cord stimulation on cerebral blood perfusion, cerebrospinal fluid catecholamine levels, and oxidative stress in comatose patients. Acta Neurochir Suppl 2008; 101: 71-76.
55. Takanashi Y, Shinonaga M: Spinal cord stimulation for cerebral vasospasm as prophylaxis. Neurol Med Chir (Tokyo) 2000; 40: 352-356.
56. Clavo B, Robaina F, Catalá L, Lloret M, Pinar B, Caramés MA, Ruiz A, Cabezón A, González G, Lara P, Ruiz-Egea E, Hernández MA: Cerebral blood flow increase in cancer patients by applying cervical spinal cord stimulation. Neurocirugia (Astur) 2007; 18: 28-32. (Pubitemid 46579841)
57. Clavo B, Robaina F, Catalá L, Pérez JL, Lloret M, Caramés MA, Morera J, López L, Suárez G, Macías D, Rivero J, Hernández MA: Effect of cervical spinal cord stimulation on regional blood flow and oxygenation in advanced head and neck tumours. Ann Oncol 2004; 15: 802-807. (Pubitemid 38714744)
58. Clavo B, Robaina F, Catala L, Valcarcel B, Morea J, Carames MA, Ruiz-Egea E, Paneo F, Lloret M, Hernandez MA: Increase locoregional BF in brain tumors after Cervical SCS. J Neurosurg 2003; 98: 1263-1270. (Pubitemid 36617931)
59. Clavo B, Robaina F, Morera J, Ruiz-Egea E, Pérez JL, Macías D, Caramés MA, Catalá L, Hernández MA, Günderoth M: Increase of brain tumor oxygenation during cervical spinal cord stimulation. Report of three cases. J Neurosurg 2002; 96: 94-100. (Pubitemid 34226546)
60. Robaina F, Clavo B: The role of spinal cord stimulation in the management of patients with brain tumors. Acta Neurochir Suppl 2007; 97: 445-543.
61. Nagamachi S, Fujita S, Nishii R, Futami S, Wakamatsu H, Yano T, Kodama T, Tamura S, Kunitake A, Uno T, Takasaki M: Alteration of regional cerebral blood flow in patients with chronic pain - evaluation before and after epidural spinal cord stimulation. Ann Nucl Med 2006; 20: 303-310. (Pubitemid 44033271)
62. Sagher O: Effects of spinal cord stimulation on cerebrovascular flow: Role of sympathetic and parasympathetic innervations. Neurosci Bull 2006; 22: 261-266. (Pubitemid 46392302)
63. Upadhyaya CD, Sagher O: Cervical spinal cord stimulation in cerebral ischemia. Acta Neurochir Suppl 2007; 97: 267-275.
64. Visocchi M, Di Rocco C, Meglio M: Protective effect of spinal cord stimulation on experimental early cerebral vasospasm. Conclusive results. Stereotact Funct Neurosurg 2001; 76: 269-275. (Pubitemid 36151240)
65. Lee JY, Huang DL, Keep R, Sagher O: Effect of electrical stimulation of the cervical spinal cord on blood flow following subarachnoid hemorrhage. J Neurosurg 2008; 109: 1148-1154.