Mechanical deformation and glycosaminoglycan content changes in a rabbit annular puncture disc degeneration model

Spine

Volumn 36, Issue 18, 2011, Pages 1438-1445

  Chan, Deva D ^a   Khan, Safdar N ^b   Ye, Xiaojing ^b   Curtiss, Shane B ^b   Gupta, Munish C ^b   Klineberg, Eric O ^b   Neu, Corey P ^a  

^a PURDUE UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

cartilage elastography; dGEMRIC; displacement encoded MRI; quantitative MRI; rabbit disc degeneration

Indexed keywords

GLYCOSAMINOGLYCAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ARTICULAR CARTILAGE; CONTROLLED STUDY; HISTOLOGY; INTERVERTEBRAL DISK DEGENERATION; LUMBAR DISK; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEUS PULPOSUS; PRIORITY JOURNAL; RABBIT; SOFT TISSUE; SPINE MOBILITY;

ANIMALS; CARTILAGE; DISEASE MODELS, ANIMAL; GADOLINIUM DTPA; GLYCOSAMINOGLYCANS; HUMANS; IMAGE ENHANCEMENT; INTERVERTEBRAL DISC DEGENERATION; INTERVERTEBRAL DISC DISPLACEMENT; LUMBAR VERTEBRAE; MAGNETIC RESONANCE IMAGING; MALE; PUNCTURES; RABBITS; REPRODUCIBILITY OF RESULTS; TIME FACTORS;

EID: 80051781615     PISSN: 03622436     EISSN: 15281159     Source Type: Journal    
DOI: 10.1097/BRS.0b013e3181f8be52     Document Type: Article

References (43)

1. Luo X, Pietrobon R, Sun SX, et al. Estimates and patterns of direct health care expenditures among individuals with back pain in the United States. Spine 2004; 29: 79-86.
2. An H, Boden SD, Kang J, et al. Summary statement: Emerging techniques for treatment of degenerative lumbar disc disease. Spine 2003; 28: S24-5.
3. Buckwalter JA. Aging and degeneration of the human intervertebral disc. Spine 1995; 20: 1307-14.
4. Singh K, Masuda K, An HS. Animal models for human disc degeneration. Spine J 2005; 5: 267S-79S.
5. Masuda K, Aota Y, Muehleman C, et al. A novel rabbit model of mild, reproducible disc degeneration by an annulus needle puncture: Correlation between the degree of disc injury and radiological and histological appearances of disc degeneration. Spine 2005; 30: 5-14.
6. Sobajima S, Kompel JF, Kim JS, et al. A slowly progressive and reproducible animal model of intervertebral disc degeneration characterized by MRI, X-ray, and histology. Spine 2005; 30: 15-24.
7. Frobin W, Brinckmann P, Biggemann M, et al. Precision measurement of disc height, vertebral height and sagittal plane displacement from lateral radiographic views of the lumbar spine. Clin Biomech (Bristol, Avon ) 1997; 12 ( suppl 1 ): S1-S63.
8. Yoon SH, Miyazaki M, Hong SW, et al. A porcine model of intervertebral disc degeneration induced by annular injury characterized with magnetic resonance imaging and histopathological fi ndings. Laboratory investigation. J Neurosurg Spine 2008; 8: 450-7.
9. Luoma K, Vehmas T, Riihimaki H, et al. Disc height and signal intensity of the nucleus pulposus on magnetic resonance imaging as indicators of lumbar disc degeneration. Spine 2001; 26: 680-6.
10. Johannessen W, Auerbach JD, Wheaton AJ, et al. Assessment of human disc degeneration and proteoglycan content using T1rhoweighted magnetic resonance imaging. Spine 2006; 31: 1253-7.
11. Perry J, Haughton V, Anderson PA, et al. The value of T2 relaxation times to characterize lumbar intervertebral disks: Preliminary results. AJNR Am J Neuroradiol 2006; 27: 337-42.
12. Neu CP, Walton JH. Displacement encoding for the measurement of cartilage deformation. Magn Reson Med 2008; 59: 149-55.
13. Chan DD, Neu CP, Hull ML. Articular cartilage deformation determined in an intact tibiofemoral joint by displacement-encoded imaging. Magn Reson Med 2009; 61: 989-93.
14. Bashir A, Gray ML, Boutin RD, et al. Glycosaminoglycan in articular cartilage: In vivo assessment with delayed Gd(DTPA)(2-)- enhanced MR imaging. Radiology 1997; 205: 551-8.
15. Huang TS, Zucherman JF, Hsu KY, et al. Gadopentetate dimeglumine as an intradiscal contrast agent. Spine 2002; 27: 839-43.
16. Niinimäki JL, Parviainen O, Ruohonen J, et al. In vivo quantifi cation of delayed gadolinium enhancement in the nucleus pulposus of human intervertebral disc. J Magn Reson Imaging 2006; 24: 796-800.
17. Noury F, Mispelter J, Szeremeta F, et al. MRI methodological development of intervertebral disc degeneration: A rabbit in vivo study at 9.4 T. Magn Reson Imaging 2008; 26: 1421-32.
18. Neu CP, Hull ML. Toward an MRI-based method to measure nonuniform cartilage deformation: An MRI-cyclic loading apparatus system and steady-state cyclic displacement of articular cartilage under compressive loading. J Biomech Eng 2003; 125: 180-8.
19. Elliott DM, Yerramalli CS, Beckstein JC, et al. The effect of relative needle diameter in puncture and sham injection animal models of degeneration. Spine 2008; 33: 588-96.
20. Antoniou J, Mwale F, Demers CN, et al. Quantitative magnetic resonance imaging of enzymatically induced degradation of the nucleus pulposus of intervertebral discs. Spine 2006; 31: 1547-54.
21. Iatridis JC, Setton LA, Weidenbaum M, et al. Alterations in the mechanical behavior of the human lumbar nucleus pulposus with degeneration and aging. J Orthop Res 1997; 15: 318-22.
22. Adams MA, McNally DS, Dolan P. "Stress" distributions inside intervertebral discs. The effects of age and degeneration. J Bone Joint Surg Br 1996; 78: 965-72.
23. Frei H, Oxland TR, Rathonyi GC, et al. The effect of nucleotomy on lumbar spine mechanics in compression and shear loading. Spine 2001; 26: 2080-9.
24. Hsieh AH, Hwang D, Ryan DA, et al. Degenerative annular changes induced by puncture are associated with insuffi ciency of disc biomechanical function. Spine 2009; 34: 998-1005.
25. Tsantrizos A, Ito K, Aebi M, et al. Internal strains in healthy and degenerated lumbar intervertebral discs. Spine 2005; 30: 2129-37.
26. Kim YE, Goel VK, Weinstein JN, et al. Effect of disc degeneration at one level on the adjacent level in axial mode. Spine 1991; 16: 331-5.
27. Antoniou J, Steffen T, Nelson F, et al. The human lumbar intervertebral disc: Evidence for changes in the biosynthesis and denaturation of the extracellular matrix with growth, maturation, ageing, and degeneration. J Clin Invest 1996; 98: 996-1003.
28. Pearce RH, Grimmer BJ, Adams ME. Degeneration and the chemical composition of the human lumbar intervertebral disc. J Orthop Res 1987; 5: 198-205.
29. Lipson SJ, Muir H. Experimental intervertebral disc degeneration: Morphologic and proteoglycan changes over time. Arthritis Rheum 1981; 24: 12-21.
30. Zhou H, Hou S, Shang W, et al. A new in vivo animal model to create intervertebral disc degeneration characterized by MRI, radiography, CT/discogram, biochemistry, and histology. Spine 2007; 32: 864-72.
31. Southern EP, Fye MA, Panjabi MM, et al. Disc degeneration: A human cadaveric study correlating magnetic resonance imaging and quantitative discomanometry. Spine 2000; 25: 2171-5.
32. Wisleder D, Smith MB, Mosher TJ, et al. Lumbar spine mechanical response to axial compression load in vivo. Spine 2001; 26: E403-9.
33. Fazey PJ, Song S, Monsas S, et al. An MRI investigation of intervertebral disc deformation in response to torsion. Clin Biomech (Bristol, Avon) 2006; 21: 538-42.
34. Boxberger JI, Sen S, Yerramalli CS, et al. Nucleus pulposus glycosaminoglycan content is correlated with axial mechanics in rat lumbar motion segments. J Orthop Res 2006; 24: 1906-15.
35. O'Connell GD, Johannessen W, Vresilovic EJ, et al. Human internal disc strains in axial compression measured noninvasively using magnetic resonance imaging. Spine 2007; 32: 2860-8.
36. Burstein D, Velyvis J, Scott KT, et al. Protocol issues for delayed Gd(DTPA)(2-)-enhanced MRI (dGEMRIC) for clinical evaluation of articular cartilage. Magn Reson Med 2001; 45: 36-41.
37. Bibby SR, Jones DA, Lee RB, et al. The pathophysiology of the intervertebral disc. Joint Bone Spine 2001; 68: 537-42.
38. Rajasekaran S, Babu JN, Arun R, et al. ISSLS prize winner: a study of diffusion in human lumbar discs: A serial magnetic resonance imaging study documenting the infl uence of the endplate on diffusion in normal and degenerate discs. Spine 2004; 29: 2654-67.
39. Nguyen-Minh C, Haughton VM, Papke RA, et al. Measuring diffusion of solutes into intervertebral disks with MR imaging and paramagnetic contrast medium. AJNR Am J Neuroradiol 1998; 19: 1781-4.
40. Liess C, Lusse S, Karger N, et al. Detection of changes in cartilage water content using MRI T2-mapping in vivo. Osteoarthritis Cartilage 2002; 10: 907-13.
41. Benneker LM, Heini PF, Anderson SE, et al. Correlation of radiographic and MRI parameters to morphological and biochemical assessment of intervertebral disc degeneration. Eur Spine J 2005; 14: 27-35.
42. Akella SV, Regatte RR, Gougoutas AJ, et al. Proteoglycan-induced changes in T1rho-relaxation of articular cartilage at 4T. Magn Reson Med 2001; 46: 419-23.
43. Nguyen A, Johannessen W, Yoder J, et al. noninvasive quantifi - cation of human nucleus pulposus pressure with use of T1 {rho}- weighted magnetic resonance imaging. J Bone Joint Surg Am 2008; 90: 796-802