Proteoglycan-induced changes in T1ρ-relaxation of articular cartilage at 4T

Magnetic Resonance in Medicine

Volumn 46, Issue 3, 2001, Pages 419-423

  Akella, Sarma V S ^a   Regatte, Ravinder Reddy ^a   Gougoutas, Alexander J ^a   Borthakur, Arijitt ^a   Shapiro, Erik M ^b   Kneeland, J Bruce ^a   Leigh, John S ^a   Reddy, Ravinder ^a  

^a HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Cartilage; MRI; Osteoarthritis; T1 relaxation

Indexed keywords

DISPERSIONS; LOCKS (FASTENERS); MAGNETIC RESONANCE IMAGING; MAMMALS; REGRESSION ANALYSIS;

ARTICULAR CARTILAGES; BOVINE ARTICULAR CARTILAGE; DEGENERATIVE CHANGES; FAST SPIN ECHOS; OSTEOARTHRITIS; ROTATING FRAME; STRONG CORRELATION; TRYPSINIZATION;

CARTILAGE;

PROTEOGLYCAN; TRYPSIN;

ANIMAL TISSUE; ARTICLE; BONE PLATE; CARTILAGE DEGENERATION; CATTLE; CONTROLLED STUDY; CORRELATION FUNCTION; DIAGNOSTIC IMAGING; DIAGNOSTIC PROCEDURE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OSTEOARTHRITIS; PATELLA; PROTEIN DEGRADATION; TIME;

EID: 0034852133     PISSN: 07403194     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrm.1208     Document Type: Article

References (36)

1. Water distribution patterns inside bovine articular cartilage as visualized by 1H magnetic resonance imaging
2. Biochemistry and metabolism of articular cartilage in osteoarthritis
3. Physicochemical properties of articular cartilage
4. The structure and function of cartilage proteoglycans
5. Structure of proteoglycans from different layers of human articular cartilage
6. Cartilage proteoglycans: Structure and potential functions
7. The correlation of fixed negative charge with glycosaminoglycan content of human articular cartilage
8. A simple physicochemical micromethod for determining fixed anionic groups in connective tissue
9. Determination of fixed charge-density in cartilage using nuclear-magnetic-resonance
10. Some biochemical and biophysical parameters for the study of the pathogenesis of osteoarthritis: A comparison between the processes of ageing and degeneration in human hip cartilage
11. Articular cartilage and osteoarthrosis. The role of molecular markers to monitor breakdown, repair and disease
12. Analysis of water-macromolecule proton magnetization transfer in articular cartilage
13. MRI contrast enhanced study of cartilage proteoglycan degradation in the rabbit knee
14. Structure, function, and degeneration of bovine hyaline cartilage: Assessment with MR imaging in vitro
15. Magnetization transfer in cartilage and its constituent macromolecules
16. Protocol issues for delayed Gd(DTPA)2-enhanced MRI (dGEMRIC) for clinical evaluation of articular cartilage
17. Gd-DTPA2 as a measure of cartilage degradation
18. Sodium visibility and quantitation in intact bovine articular cartilage using high field 23Na MRI and MRS
19. Sodium MRI of human articular cartilage in vivo
20. Gd-DTPA relaxivity depends on macromolecular content
21. A method for T1 rho imaging
22. Spin locking for magnetic resonance imaging with application to human breast
23. 1ρ-relaxation in articular cartilage: Effects of enzymatic degradation
24. The role of relaxation times in monitoring proteoglycan depletion in articular cartilage
25. Sensitivity of MRI to proteoglycan depletion in cartilage: Comparison of sodium and proton MRI
26. A direct spectrophotometric microassay for sulfated glycosaminoglycans in cartilage cultures
27. Detection of 17O by proton T1 rho dispersion imaging
28. Volume-selective determination of the spin-lattice relaxation time in the rotating frame T1 rho, and T1 rho imaging
29. MR-microscopic visualization of anisotropic internal cartilage structures using the magic angle technique
30. Relaxation anisotropy in cartilage by NMR microscopy (μMRI) at 14-μm resolution
31. Off-resonance spin locking for MR imaging
32. One-shot measurement of spin-lattice relaxation times in the off-resonance rotating frame using MR imaging, with application to breast
33. A pulsed NMR study of nuclear spin-lattice relaxation in the off-resonance rotating frame
34. SAR and B1 field distributions in a heterogeneous human head model within a birdcage coil. Specific energy absorption rate