Vitamin D deficiency, statin-related myopathy and other links with vascular risk

Current Medical Research and Opinion

Volumn 27, Issue 9, 2011, Pages 1691-1692

  Katsiki, N ^a   Athyros, V G ^b   Karagiannis, A ^b   Mikhailidis, D P ^c  

^a AHEPA UNIVERSITY HOSPITAL   (Greece)

^b ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^c ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

Myopathy; Statins; Vascular risk; Vitamin D

Indexed keywords

25 HYDROXYVITAMIN D; ATORVASTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; ROSUVASTATIN; TRIACYLGLYCEROL; VITAMIN D;

BLOOD PRESSURE; CARDIOVASCULAR RISK; DIABETES MELLITUS; DISEASE ASSOCIATION; DYSLIPIDEMIA; EDITORIAL; HUMAN; HYPERTENSION; INSULIN RESISTANCE; METABOLIC SYNDROME X; MYALGIA; MYOPATHY; MYOSITIS; OBESITY; PATIENT COMPLIANCE; TREATMENT OUTCOME; VITAMIN BLOOD LEVEL; VITAMIN D DEFICIENCY; VITAMIN SUPPLEMENTATION;

FEMALE; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; HYPERCHOLESTEROLEMIA; MALE; MUSCULAR DISEASES; MYOSITIS; VITAMIN D; VITAMIN D DEFICIENCY;

EID: 80051773631     PISSN: 03007995     EISSN: 14734877     Source Type: Journal    
DOI: 10.1185/03007995.2011.598922     Document Type: Editorial

References (33)

1. Glueck C, Budhani S, Khan A, et al. Vitamin D deficiency, myositis-myalgia and reversible statin intolerance. Curr Med Res Opin 2011; in press
2. Tziomalos K, Athyros VG, Karagiannis A, et al. Management of statin-intolerant high-risk patients. Curr Vasc Pharmacol 2010;8:632-637
3. Kiortsis DN, Filippatos TD, Mikhailidis DP, et al. Statin-associated adverse effects beyond muscle and liver toxicity. Atherosclerosis 2007;195:7-16 (Pubitemid 47561937)
4. Daskalopoulou SS. When statin therapy stops: implications for the patient. Curr Opin Cardiol 2009;24:454-460
5. Tziomalos K, Athyros VG, Mikhailidis DP. Statin discontinuation: an underestimated risk? Curr Med Res Opin 2008;24:3059-3062
6. Kumar J, Muntner P, Kaskel FJ, et al. Prevalence and associations of 25-hydroxyvitamin D deficiency in US children: NHANES 2001-2004. Pediatrics 2009;124:e362-370
7. Jorde R, Sneve M, Hutchinson M, et al. Tracking of serum 25-hydroxyvitamin D levels during 14 years in a population-based study and during 12 months in an intervention study. Am J Epidemiol 2010;171:903-908
8. Adams JS, Hewison M. Update in vitamin D. J Clin Endocrinol Metab 2010;95:471-478
9. Anagnostis P, Athyros VG, Adamidou F, et al. Vitamin D and cardiovascular disease: a novel agent for reducing cardiovascular risk? Curr Vasc Pharmacol 2010;8:720-730
10. Florentin M, Elisaf MS, Mikhailidis DP, Liberopoulos EN. Vitamin D and metabolic syndrome: is there a link? Curr Pharm Des 2010;16:3417-3434
11. Kayaniyil S, Vieth R, Harris SB, et al. Association of 25(OH)D and PTH with metabolic syndrome and its traditional and nontraditional components. J Clin Endocrinol Metab 2011;96:168-175
12. Lu L, Yu Z, Pan A, et al. Plasma 25-hydroxyvitamin D concentration and metabolic syndrome among middle-aged and elderly Chinese individuals. Diabetes Care 2009;32:1278-1283
13. Williams DM, Fraser A, Lawlor DA. Associations of vitamin D, parathyroid hormone and calcium with cardiovascular risk factors in US adolescents. Heart 2011;97:315-320
14. Johnson MD, Nader NS, Weaver AL, et al. Relationships between 25-hydroxyvitamin D levels and plasma glucose and lipid levels in pediatric outpatients. J Pediatr 2010;156:444-449
15. Patel P, Poretsky L, Liao E. Lack of effect of subtherapeutic vitamin D treatment on glycemic and lipid parameters in Type 2 diabetes: a pilot prospective randomized trial. J Diabetes 2010;2:36-40
16. Tzotzas T, Papadopoulou FG, Tziomalos K, et al. Rising serum 25-hydroxyvitamin D levels after weight loss in obese women correlate with improvement in insulin resistance. J Clin Endocrinol Metab 2010;95:4251-4257
17. Muscogiuri G, Sorice GP, Prioletta A, et al. 25-Hydroxyvitamin D concentration correlates with insulin-sensitivity and BMI in obesity. Obesity (Silver Spring) 2010;18:1906-1910
18. Reis JP, von Mü hlen D, Miller 3rd ER, et al. Vitamin D status and cardiometabolic risk factors in the United States adolescent population. Pediatrics 2009;124:e371-379
19. Rodríguez-Rodríguez E, Ortega RM, Gonzá lez-Rodríguez LG, Ló pez-Sobaler AM; UCM Research Group VALORNUT (920030). Vitamin D deficiency is an independent predictor of elevated triglycerides in Spanish school children. Eur J Nutr 2010 Nov 20 [Epub ahead of print]
20. Rajpathak SN, Xue X, Wassertheil-Smoller S, et al. Effect of 5 y of calcium plus vitamin D supplementation on change in circulating lipids: results from the Women's Health Initiative. Am J Clin Nutr 2010;91:894-899
21. Scragg R, Holdaway I, Jackson R, et al. Plasma 25-hydroxyvitamin D3 and its relation to physical activity and other heart disease risk factors in the general population. Ann Epidemiol 1992;2:697-703
22. Jorde R, Figenschau Y, Hutchinson M, et al. High serum 25-hydroxyvitamin D concentrations are associated with a favourable serum lipid profile. Eur J Clin Nutr 2010;64:1457-1464
23. Williams DM, Fraser A, Lawlor DA. Associations of vitamin D, parathyroid hormone and calcium with cardiovascular risk factors in US adolescents. Heart 2011;97:315-320
24. Karhapä ä P, Pihlajamä ki J, Pö rsti I, et al. Diverse associations of 25-hydroxyvitamin D and 1,25-dihydroxy-vitamin D with dyslipidaemias. J Intern Med 2010;268:604-610
25. Maki KC, Rubin MR, Wong LG, et al. Serum 25-hydroxyvitamin D is independently associated with high-density lipoprotein cholesterol and the metabolic syndrome in men and women. J Clin Lipidol 2009;3:289-296
26. Kazlauskaite R, Powell LH, Mandapakala C, et al. Vitamin D is associated with atheroprotective high-density lipoprotein profile in postmenopausal women. J Clin Lipidol 2010;4:113-119
27. Witham MD, Dove FJ, Sugden JA, et al. The effect of vitamin D replacement on markers of vascular health in stroke patients-a randomised controlled trial. Nutr Metab Cardiovasc Dis 2010 Dec 29 [Epub ahead of print]
28. Witham MD, Nadir MA, Struthers AD. Effect of vitamin D on blood pressure: a systematic review and meta-analysis. J Hypertens 2009;27:1948-1954
29. Pilz S, Tomaschitz A, Ritz E, Pieber TR; Medscape. Vitamin D status and arterial hypertension: a systematic review. Nat Rev Cardiol 2009;6:621-630
30. Ertugrul DT, Yavuz B, Cil H, et al. STATIN-D Study: comparison of the influences of rosuvastatin and fluvastatin treatment on the levels of 25 hydroxyvitamin D. Cardiovasc Ther 2010 Mar 27 [Epub ahead of print]
31. Pé rez-Castrilló n JL, Vega G, Abad L, et al. Effects of atorvastatin on vitamin D levels in patients with acute ischemic heart disease. Am J Cardiol 2007;99:903-905 (Pubitemid 46483276)
32. Pé rez-Castrilló n JL, Abad Manteca L, Vega G, et al. Vitamin D levels and lipid response to atorvastatin. Int J Endocrinol 2010;2010:320721
33. Vandenberg BF, Robinson J. Management of the patient with statin intolerance. Curr Atheroscler Rep 2010;12:48-57