Targeting of T/Tn antigens with a plant lectin to kill human leukemia cells by photochemotherapy

PLoS ONE

Volumn 6, Issue 8, 2011, Pages

  Poiroux, Guillaume ^a,b   Pitié, Marguerite ^c   Culerrier, Raphaël ^b   Lafont, Elodie ^a,b   Ségui, Bruno ^a,b   van Damme, Els J M ^d   Peumans, Willy J ^d   Bernadou, Jean ^b,c   Levade, Thierry ^a   Rougé, Pierre ^b   Barre, Annick ^b   Benoist, Hervé ^a,b  

^a CHU RANGUEIL   (France)

^b UNIVERSITÉ DE TOULOUSE   (France)

^c LCC LABORATOIRE DE CHIMIE DE COORDINATION   (France)

^d GHENT UNIVERSITY   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

5 [4 (5 CARBOXY 1 BUTOXY)PHENYL] 10,15,20 TRIS(4 N METHYL)PYRIDINIUMYL PORPHYRIN MORNIGA G CONJUGATE; ANTILEUKEMIC AGENT; CASPASE; GLYCAN; PHOTOSENSITIZING AGENT; TN ANTIGEN; UNCLASSIFIED DRUG; 5 (4 (5 CARBOXY 1 BUTOXY)PHENYL) 10,15,20 TRIS(4 N METHYL)PYRIDINIUMYLPORPHYRIN; 5-(4-(5-CARBOXY-1-BUTOXY)PHENYL)-10,15,20-TRIS(4-N-METHYL)PYRIDINIUMYLPORPHYRIN; MORNIGA G PROTEIN, MORUS NIGRA; PLANT LECTIN; PORPHYRIN; TUMOR ANTIGEN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL KILLING; CHRONIC LYMPHATIC LEUKEMIA; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG TARGETING; GLYCOSYLATION; HUMAN; HUMAN CELL; LEUKEMIA CELL; LEUKEMIA CELL LINE; LIGHT IRRADIANCE; PHOTOCHEMOTHERAPY; PHOTOSENSITIZATION; PHOTOTOXICITY; SIGNAL TRANSDUCTION; APOPTOSIS; CELL CULTURE; CELL LINE; CELL STRAIN HL 60; CELL STRAIN K 562; CELL STRAIN U937; CELL SURVIVAL; CHEMISTRY; DOSE RESPONSE; DRUG EFFECT; LEUKEMIA; METABOLISM; METHODOLOGY; PATHOLOGY; RADIATION EXPOSURE; TUMOR CELL LINE;

ANTIGENS, TUMOR-ASSOCIATED, CARBOHYDRATE; APOPTOSIS; CASPASES; CELL LINE; CELL LINE, TUMOR; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; HL-60 CELLS; HUMANS; JURKAT CELLS; K562 CELLS; LEUKEMIA; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; PLANT LECTINS; PORPHYRINS; U937 CELLS;

EID: 80051769519     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0023315     Document Type: Article

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