Photolon™, a chlorin e6 derivative, triggers ROS production and light-dependent cell death via necrosis

International Journal of Biochemistry and Cell Biology

Volumn 40, Issue 2, 2008, Pages 227-235

  Copley, Louise ^a   van der Watt, Pauline ^a   Wirtz, Karel W ^b   Parker, M Iqbal ^a   Leaner, Virna D ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Cancer; Necrosis; Photodynamic therapy; Photolon (Fotolon); ROS production

Indexed keywords

CASPASE 3; CASPASE 7; LACTATE DEHYDROGENASE; PHOTOLON; POVIDONE; REACTIVE OXYGEN METABOLITE; SCAVENGER; TALAPORFIN; TROLOX C; UNCLASSIFIED DRUG; CHLORIN E6; PORPHYRIN; PROTOPORPHYRIN; RADIOSENSITIZING AGENT;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL DEATH; CELL KILLING; CONTROLLED STUDY; CULTURE MEDIUM; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME RELEASE; HUMAN; HUMAN CELL; PHOTODYNAMIC THERAPY; CELL CULTURE; CELL PROLIFERATION; CELL SURVIVAL; CHEMICALLY INDUCED DISORDER; CHEMISTRY; DRUG SCREENING; LIGHT; METABOLISM; METHODOLOGY; NECROSIS; NEOPLASM; PATHOLOGY; PHOTOCHEMOTHERAPY;

CELL DEATH; CELL PROLIFERATION; CELL SURVIVAL; DRUG EVALUATION, PRECLINICAL; HUMANS; LIGHT; NECROSIS; NEOPLASMS; PHOTOCHEMOTHERAPY; PORPHYRINS; PROTOPORPHYRINS; RADIATION-SENSITIZING AGENTS; REACTIVE OXYGEN SPECIES; TUMOR CELLS, CULTURED;

EID: 36248933765     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2007.07.014     Document Type: Article

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