메뉴 건너뛰기




Volumn 52, Issue 6, 2011, Pages 3506-3513

The role of the prostaglandin EP 4 receptor in the regulation of human outflow facility

Author keywords

[No Author keywords available]

Indexed keywords

3 7 DITHIA PROSTAGLANDIN E1; 6 ISOPROPOXY 9 OXO 2 XANTHENECARBOXYLIC ACID; BETA ARRESTIN; CYCLIC AMP; GW 627368; PROSTAGLANDIN E RECEPTOR 4; PROSTAGLANDIN RECEPTOR BLOCKING AGENT; PROSTAGLANDIN RECEPTOR STIMULATING AGENT; UNCLASSIFIED DRUG; 3,7 DITHIA(11 ALPHA,13E,15S) 11,15 DIHYDROXY 9 OXOPROST 13 EN 1 OIC ACID; 3,7-DITHIA(11 ALPHA,13E,15S)-11,15-DIHYDROXY-9-OXOPROST-13-EN-1-OIC ACID; DRUG DERIVATIVE; ISOINDOLE DERIVATIVE; N (2 (4 (4,9 DIETHOXY 1 OXO 1,3 DIHYDRO 2H BENZO(F)ISOINDOL 2 YL)PHENYL)ACETYL)BENZENE SULPHONAMIDE; N-(2-(4-(4,9-DIETHOXY-1-OXO-1,3-DIHYDRO-2H-BENZO(F)ISOINDOL-2-YL)PHENYL)ACETYL)BENZENE SULPHONAMIDE; PROSTAGLANDIN E1; RETINA S ANTIGEN; SULFONAMIDE;

EID: 80051765713     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.10-6510     Document Type: Article
Times cited : (26)

References (30)
  • 1
    • 0029980777 scopus 로고    scopus 로고
    • Number of people with glaucoma worldwide
    • Quigley HA. Number of people with glaucoma worldwide. Br J Ophthalmol. 1996;80(5):389-393.
    • (1996) Br J Ophthalmol , vol.80 , Issue.5 , pp. 389-393
    • Quigley, H.A.1
  • 2
    • 0019352719 scopus 로고
    • Correlations between intraocular pressure, visual field and visual acuity, based on 11 years of observations of treated chronic glaucomas
    • Niesel P, Flammer J. Correlations between intraocular pressure, visual field and visual acuity, based on 11 years of observations of treated chronic glaucomas. Int Ophthalmol. 1980;3(1):31-35.
    • (1980) Int Ophthalmol , vol.3 , Issue.1 , pp. 31-35
    • Niesel, P.1    Flammer, J.2
  • 3
    • 0024474249 scopus 로고
    • Prostaglandin F2 alpha increases uveoscleral outflow in the cynomolgus monkey
    • Gabelt BT, Kaufman PL. Prostaglandin F2 alpha increases uveoscleral outflow in the cynomolgus monkey. Exp Eye Res. 1989;49(3): 389-402.
    • (1989) Exp Eye Res , vol.49 , Issue.3 , pp. 389-402
    • Gabelt, B.T.1    Kaufman, P.L.2
  • 4
  • 5
    • 37249029889 scopus 로고    scopus 로고
    • Prostaglandins increase trabecular meshwork outflow facility in cultured human anterior segments
    • Bahler CK, Howell KG, Hann CR, Fautsch MP, Johnson DH. Prostaglandins increase trabecular meshwork outflow facility in cultured human anterior segments. Am J Ophthalmol. 2008;145(1): 114-119.
    • (2008) Am J Ophthalmol , vol.145 , Issue.1 , pp. 114-119
    • Bahler, C.K.1    Howell, K.G.2    Hann, C.R.3    Fautsch, M.P.4    Johnson, D.H.5
  • 6
    • 0032712665 scopus 로고    scopus 로고
    • Responses of intraocular pressure and the pupil of feline eyes to prostaglandin EP1 and FP receptor agonists
    • Bhattacherjee P, Williams BS, Paterson CA. Responses of intraocular pressure and the pupil of feline eyes to prostaglandin EP1 and FP receptor agonists. Invest Ophthalmol Vis Sci. 1999;40(12): 3047-3053.
    • (1999) Invest Ophthalmol Vis Sci , vol.40 , Issue.12 , pp. 3047-3053
    • Bhattacherjee, P.1    Williams, B.S.2    Paterson, C.A.3
  • 7
    • 0032589354 scopus 로고    scopus 로고
    • Flow after prostaglandin E1 is mediated by receptor-coupled adenylyl cyclase in human anterior segments
    • Dijkstra BG, Schneemann A, Hoyng PF. Flow after prostaglandin E1 is mediated by receptor-coupled adenylyl cyclase in human anterior segments. Invest Ophthalmol Vis Sci. 1999;40(11):2622-2626.
    • (1999) Invest Ophthalmol Vis Sci , vol.40 , Issue.11 , pp. 2622-2626
    • Dijkstra, B.G.1    Schneemann, A.2    Hoyng, P.F.3
  • 8
    • 70349464680 scopus 로고    scopus 로고
    • Ocular pharmacokinetics and hypotensive activity of PF-04475270, an EP4 prostaglandin agonist in preclinical models
    • Prasanna G, Fortner J, Xiang C, et al. Ocular pharmacokinetics and hypotensive activity of PF-04475270, an EP4 prostaglandin agonist in preclinical models. Exp Eye Res. 2009;89(5):608-617.
    • (2009) Exp Eye Res , vol.89 , Issue.5 , pp. 608-617
    • Prasanna, G.1    Fortner, J.2    Xiang, C.3    et al4
  • 9
    • 67649961681 scopus 로고    scopus 로고
    • Prostanoid EP4 receptor stimulation produces ocular hypotension by a mechanism that does not appear to involve uveoscleral outflow
    • Woodward DF, Nilsson SF, Toris CB, Kharlamb AB, Nieves AL, Krauss AH. Prostanoid EP4 receptor stimulation produces ocular hypotension by a mechanism that does not appear to involve uveoscleral outflow. Invest Ophthalmol Vis Sci. 2009;50(7):3320-3328.
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , Issue.7 , pp. 3320-3328
    • Woodward, D.F.1    Nilsson, S.F.2    Toris, C.B.3    Kharlamb, A.B.4    Nieves, A.L.5    Krauss, A.H.6
  • 10
    • 0025572673 scopus 로고
    • EP3, but not EP2, FP, or TP prostanoid-receptor stimulation may reduce intraocular pressure
    • Waterbury LD, Eglen RM, Faurot GF, Cooper GF. EP3, but not EP2, FP, or TP prostanoid-receptor stimulation may reduce intraocular pressure. Invest Ophthalmol Vis Sci. 1990;31(12):2560-2567.
    • (1990) Invest Ophthalmol Vis Sci , vol.31 , Issue.12 , pp. 2560-2567
    • Waterbury, L.D.1    Eglen, R.M.2    Faurot, G.F.3    Cooper, G.F.4
  • 11
    • 0023161827 scopus 로고
    • Effects of topical PGF2 alpha on aqueous humor dynamics in cynomolgus monkeys
    • Crawford K, Kaufman PL, Gabelt BT. Effects of topical PGF2 alpha on aqueous humor dynamics in cynomolgus monkeys. Curr Eye Res. 1987;6(8):1035-1044.
    • (1987) Curr Eye Res , vol.6 , Issue.8 , pp. 1035-1044
    • Crawford, K.1    Kaufman, P.L.2    Gabelt, B.T.3
  • 12
    • 0032774749 scopus 로고    scopus 로고
    • AL-8810: A novel prostaglandin F2 alpha analog with selective antagonist effects at the prostaglandin F2 alpha (FP) receptor
    • Griffin BW, Klimko P, Crider JY, Sharif NA. AL-8810: a novel prostaglandin F2 alpha analog with selective antagonist effects at the prostaglandin F2 alpha (FP) receptor. J Pharmacol Exp Ther. 1999;290(3):1278-1284.
    • (1999) J Pharmacol Exp Ther , vol.290 , Issue.3 , pp. 1278-1284
    • Griffin, B.W.1    Klimko, P.2    Crider, J.Y.3    Sharif, N.A.4
  • 13
    • 0035015421 scopus 로고    scopus 로고
    • Potential mechanism for the additivity of pilocarpine and latanoprost
    • Toris CB, Zhan GL, Zhao J, Camras CB, Yablonski ME. Potential mechanism for the additivity of pilocarpine and latanoprost. Am J Ophthalmol. 2001;131(6):722-728.
    • (2001) Am J Ophthalmol , vol.131 , Issue.6 , pp. 722-728
    • Toris, C.B.1    Zhan, G.L.2    Zhao, J.3    Camras, C.B.4    Yablonski, M.E.5
  • 14
    • 84863736356 scopus 로고    scopus 로고
    • Bimatoprost effects on aqueous humor dynamics in monkeys
    • Woodward DF, Krauss AH, Nilsson SF. Bimatoprost effects on aqueous humor dynamics in monkeys. J Ophthalmol. 2010;2010: 926192.
    • (2010) J Ophthalmol. , vol.2010 , pp. 926192
    • Woodward, D.F.1    Krauss, A.H.2    Nilsson, S.F.3
  • 15
    • 0027379360 scopus 로고
    • The effects on aqueous dynamics of PhXA41, a new prostaglandin F2 alpha analogue, after topical application in normal and ocular hypertensive human eyes
    • Ziai N, Dolan JW, Kacere RD, Brubaker RF. The effects on aqueous dynamics of PhXA41, a new prostaglandin F2 alpha analogue, after topical application in normal and ocular hypertensive human eyes. Arch Ophthalmol. 1993;111(10):1351-1358.
    • (1993) Arch Ophthalmol , vol.111 , Issue.10 , pp. 1351-1358
    • Ziai, N.1    Dolan, J.W.2    Kacere, R.D.3    Brubaker, R.F.4
  • 16
    • 0029040392 scopus 로고
    • Isolation and culture of human trabecular meshwork cells by extracellular matrix digestion
    • Stamer WD, Seftor RE, Williams SK, Samaha HA, Snyder RW. Isolation and culture of human trabecular meshwork cells by extracellular matrix digestion. Curr Eye Res. 1995;14(7):611-617.
    • (1995) Curr Eye Res , vol.14 , Issue.7 , pp. 611-617
    • Stamer, W.D.1    Seftor, R.E.2    Williams, S.K.3    Samaha, H.A.4    Snyder, R.W.5
  • 17
    • 0031704907 scopus 로고    scopus 로고
    • Isolation, culture, and characterization of endothelial cells from Schlemm's canal
    • Stamer WD, Roberts BC, Howell DN, Epstein DL. Isolation, culture, and characterization of endothelial cells from Schlemm's canal. Invest Ophthalmol Vis Sci. 1998;39(10):1804-1812.
    • (1998) Invest Ophthalmol Vis Sci , vol.39 , Issue.10 , pp. 1804-1812
    • Stamer, W.D.1    Roberts, B.C.2    Howell, D.N.3    Epstein, D.L.4
  • 18
    • 0037169557 scopus 로고    scopus 로고
    • Phosphorylation of glycogen synthase kinase-3 and stimulation of T-cell factor signaling following activation of EP2 and EP4 prostanoid receptors by prostaglandin E2
    • Fujino H, West KA, Regan JW. Phosphorylation of glycogen synthase kinase-3 and stimulation of T-cell factor signaling following activation of EP2 and EP4 prostanoid receptors by prostaglandin E2. J Biol Chem. 2002;25 277(4):2614-2619.
    • (2002) J Biol Chem. , vol.25-277 , Issue.4 , pp. 2614-2619
    • Fujino, H.1    West, K.A.2    Regan, J.W.3
  • 20
    • 70350719236 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate effects on the inner wall of Schlemm's canal and outflow facility in perfused human eyes
    • Stamer WD, Read AT, Sumida GM, Ethier CR. Sphingosine-1-phosphate effects on the inner wall of Schlemm's canal and outflow facility in perfused human eyes. Exp Eye Res. 2009;89(6):980-988.
    • (2009) Exp Eye Res , vol.89 , Issue.6 , pp. 980-988
    • Stamer, W.D.1    Read, A.T.2    Sumida, G.M.3    Ethier, C.R.4
  • 21
    • 0027168927 scopus 로고
    • An improved ocular perfusion system
    • Ethier CR, Ajersch P, Pirog R. An improved ocular perfusion system. Curr Eye Res. 1993;12(8):765-770.
    • (1993) Curr Eye Res , vol.12 , Issue.8 , pp. 765-770
    • Ethier, C.R.1    Ajersch, P.2    Pirog, R.3
  • 22
    • 0036242462 scopus 로고    scopus 로고
    • Expression and localization of FP and EP prostanoid receptor subtypes in human ocular tissues
    • Schlotzer-Schrehardt U, Zenkel M, Nusing RM. Expression and localization of FP and EP prostanoid receptor subtypes in human ocular tissues. Invest Ophthalmol Vis Sci. 2002;43(5):1475-1487.
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , Issue.5 , pp. 1475-1487
    • Schlotzer-Schrehardt, U.1    Zenkel, M.2    Nusing, R.M.3
  • 23
    • 0033024889 scopus 로고    scopus 로고
    • Localization of functional prostaglandin E2 receptors EP3 and EP4 in the nuclear envelope
    • Bhattacharya M, Peri K, Ribeiro-da-Silva A, et al. Localization of functional prostaglandin E2 receptors EP3 and EP4 in the nuclear envelope. J Biol Chem. 1999;274(22):15719-15724.
    • (1999) J Biol Chem , vol.274 , Issue.22 , pp. 15719-15724
    • Bhattacharya, M.1    Peri, K.2    Ribeiro-da-Silva, A.3    et al4
  • 25
    • 0035069805 scopus 로고    scopus 로고
    • Functional pharmacological evidence for EP2 and EP4 prostanoid receptors in immortalized human trabecular meshwork and non-pigmented ciliary epithelial cells
    • Crider JY, Sharif NA. Functional pharmacological evidence for EP2 and EP4 prostanoid receptors in immortalized human trabecular meshwork and non-pigmented ciliary epithelial cells. J Ocul Pharmacol Ther. 2001;17(1):35-46.
    • (2001) J Ocul Pharmacol Ther , vol.17 , Issue.1 , pp. 35-46
    • Crider, J.Y.1    Sharif, N.A.2
  • 26
    • 77958127619 scopus 로고    scopus 로고
    • Cellular basis for bimatoprost effects on human conventional outflow
    • Stamer WD, Piwnica D, Jolas T, et al. Cellular basis for bimatoprost effects on human conventional outflow. Invest Ophthalmol Vis Sci. 2010;51(10);5176-5181.
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , Issue.10 , pp. 5176-5181
    • Stamer, W.D.1    Piwnica, D.2    Jolas, T.3    et al4
  • 27
    • 22344439814 scopus 로고    scopus 로고
    • Differential regulation of phosphorylation of the cAMP response element-binding protein after activation of EP2 and EP4 prostanoid receptors by prostaglandin E2
    • Fujino H, Salvi S, Regan JW. Differential regulation of phosphorylation of the cAMP response element-binding protein after activation of EP2 and EP4 prostanoid receptors by prostaglandin E2. Mol Pharmacol. 2005;68(1):251-259.
    • (2005) Mol Pharmacol , vol.68 , Issue.1 , pp. 251-259
    • Fujino, H.1    Salvi, S.2    Regan, J.W.3
  • 28
    • 0028849877 scopus 로고
    • 6-Isopropoxy-9-oxoxanthene-2-carboxylic acid (AH6809), a human EP2 receptor antagonist
    • Woodward DF, Pepperl DJ, Burkey TH, et al. 6-Isopropoxy-9-oxoxanthene-2-carboxylic acid (AH6809), a human EP2 receptor antagonist. Biochem Pharmacol. 1995;50:1731-1732.
    • (1995) Biochem Pharmacol. , vol.50 , pp. 1731-1732
    • Woodward, D.F.1    Pepperl, D.J.2    Burkey, T.H.3    et al4
  • 29
    • 0030221225 scopus 로고    scopus 로고
    • Interaction of BW A868C, a prostanoid DP-receptor antagonist, with two receptor subtypes in the rabbit isolated saphenous vein
    • Lydford SJ, McKechnie KC, Leff P. Interaction of BW A868C, a prostanoid DP-receptor antagonist, with two receptor subtypes in the rabbit isolated saphenous vein. Prostaglandins. 1996;52(2): 125-139.
    • (1996) Prostaglandins , vol.52 , Issue.2 , pp. 125-139
    • Lydford, S.J.1    McKechnie, K.C.2    Leff, P.3
  • 30
    • 0023160293 scopus 로고
    • Iloprost, a stable prostacyclin analog, reduces intraocular pressure
    • Hoyng PF, de Jong N. Iloprost, a stable prostacyclin analog, reduces intraocular pressure. Invest Ophthalmol Vis Sci. 1987;3: 470-476.
    • (1987) Invest Ophthalmol Vis Sci. , vol.3 , pp. 470-476
    • Hoyng, P.F.1    de Jong, N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.