Evaluation of 64Cu-labeled bifunctional Chelate-Bombesin conjugates

Bioconjugate Chemistry

Volumn 22, Issue 8, 2011, Pages 1729-1735

  Ait Mohand, Samia ^a   Fournier, Patrick ^a   Dumulon Perreault, Véronique ^a   Kiefer, Garry E ^b   Jurek, Paul ^b   Ferreira, Cara L ^c   Bénard, François ^d   Guérin, Brigitte ^a  

^a UNIVERSITY OF SHERBROOKE   (Canada)

^b Macrocyclics   (United States)

^c MDS Inc   (Canada)

^d BRITISH COLUMBIA CANCER AGENCY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANILINE; BAYESIAN NETWORKS; BINDING ENERGY; DISEASES; PEPTIDES; RESINS;

BI-FUNCTIONAL; BINDING AFFINITIES; HIGH AFFINITY; IN-VITRO; IN-VIVO; LABELINGS; PEPTIDE RECEPTOR; PET IMAGING; RECEPTOR BINDING; SOLID SUPPORTS;

CHELATION;

1 OXA 4,7,10 TRIAZACYCLODODECANE 4,7,10 TRIACETIC ACID CU 64; 1,4,7 TRIAZACYCLONONANE 1,4,7 TRIACETIC ACID CU 64; 1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID CU 64; 2 (1H 7 AZABENZOTRIAZOL 1 YL) 1,1,3,3 TETRAMETHYLURONIUM HEXAFLUOROPHOSPHATE; 3 (DIETHOXY PHOSPHORYLOXY) 3H BENZO[D][1,2,3]TRIAZIN 4 ONE; 3,6,9,15 TETRAAZABICYCLO[9.3.1]PENTA DECA 1 (15),11,13 TRIENE 3,6,9 TRIACETIC ACID CU 64; 6 CHLORO 1 HYDROXY 1H BENZOTRIAZOLE; AMMONIUM ACETATE; BOMBESIN; CARBOXYLIC ACID; CHELATING AGENT; COPPER 64; GASTRIN RELEASING PEPTIDE RECEPTOR; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG; 1,4,7,10-TETRAAZACYCLODODECANE- 1,4,7,10-TETRAACETIC ACID; BOMBESIN RECEPTOR; COPPER; DIAGNOSTIC AGENT; PEPTIDE; SINGLE HETEROCYCLIC RINGS; TETRAXETAN;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; BREAST CANCER; CANCER CELL; CHEMICAL BOND; CONJUGATE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INCUBATION TEMPERATURE; ISOTOPE LABELING; MOUSE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PROTEIN EXPRESSION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; STRUCTURE ANALYSIS; BINDING COMPETITION; BREAST TUMOR; CHEMISTRY; EVALUATION; METABOLISM; METHODOLOGY; SCINTISCANNING; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE;

MUS;

BINDING, COMPETITIVE; BOMBESIN; BREAST NEOPLASMS; CELL LINE, TUMOR; CHELATING AGENTS; COPPER RADIOISOTOPES; DRUG STABILITY; FEMALE; HETEROCYCLIC COMPOUNDS, 1-RING; HUMANS; PEPTIDES; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; RECEPTORS, BOMBESIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 80051733729     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc2002665     Document Type: Article

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