메뉴 건너뛰기




Volumn 17, Issue 4, 2011, Pages 293-297

The effect of N-acetyl cysteine on serum glutathione, TNF-α and tissue malondialdehyde levels in the treatment of sepsis;Sepsis tedavisinde N-asetilsistein'in serum glutatyon, TNF-α ve doku malondialdehid düzeylerine etkisi

Author keywords

Glutathione; Malondialdehyde; N acetyl cysteine; Sepsis; Tumor necrosis factor

Indexed keywords

ACETYLCYSTEINE; GLUTATHIONE; MALONALDEHYDE; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA;

EID: 80051720801     PISSN: 1306696X     EISSN: None     Source Type: Journal    
DOI: 10.5505/tjtes.2011.66743     Document Type: Article
Times cited : (12)

References (18)
  • 1
    • 52649135665 scopus 로고    scopus 로고
    • Epidemiology of severe sepsis in the intensive care unit
    • Vincent JL, Atalan HK. Epidemiology of severe sepsis in the intensive care unit. Br J Hosp Med (Lond) 2008;69(8):442-3.
    • (2008) Br J Hosp Med (Lond) , vol.69 , Issue.8 , pp. 442-443
    • Vincent, J.L.1    Atalan, H.K.2
  • 2
    • 0029941532 scopus 로고    scopus 로고
    • The sepsis syndrome. Defnition and general approach to management
    • Bone RC. The sepsis syndrome. Defnition and general approach to management. Clin Chest Med 1996;17:175-81.
    • (1996) Clin Chest Med , vol.17 , pp. 175-181
    • Bone, R.C.1
  • 3
    • 33846101162 scopus 로고    scopus 로고
    • N-acetylcysteine exerts protective effects and prevents lung redox imbalance and peroxynitrite generation in endotoxemic rats
    • Carbonell LF, Díaz J, Hernández I, Cuevas S, Valero F, Que-sada T, et al. N-acetylcysteine exerts protective effects and prevents lung redox imbalance and peroxynitrite generation in endotoxemic rats. Med Chem 2007;3:29-34.
    • (2007) Med Chem , vol.3 , pp. 29-34
    • Carbonell, L.F.1    Díaz, J.2    Hernández, I.3    Cuevas, S.4    Valero, F.5    Que-Sada, T.6
  • 4
    • 77953545552 scopus 로고    scopus 로고
    • Effects of N-acetylcysteine/deferox-amine, taurine and RC-3095 on respiratory chain complexes and creatine kinase activities in rat brain after sepsis
    • Cassol OJ Jr, Rezin GT, Petronilho FC, Scaini G, Gonçalves CL, Ferreira GK, et al. Effects of N-acetylcysteine/deferox-amine, taurine and RC-3095 on respiratory chain complexes and creatine kinase activities in rat brain after sepsis. Neuro-chem Res 2010;35:515-21.
    • (2010) Neuro-chem Res , vol.35 , pp. 515-521
    • Cassol Jr., O.J.1    Rezin, G.T.2    Petronilho, F.C.3    Scaini, G.4    Gonçalves, C.L.5    Ferreira, G.K.6
  • 5
    • 0345018815 scopus 로고    scopus 로고
    • N-acetylcysteine: Pharmacological considerations and experimental and clinical applications
    • Cotgreave IA. N-acetylcysteine: pharmacological considerations and experimental and clinical applications. Adv Pharmacol 1997;38:205-27.
    • (1997) Adv Pharmacol , vol.38 , pp. 205-227
    • Cotgreave, I.A.1
  • 6
    • 0034724653 scopus 로고    scopus 로고
    • N-acetylcysteine suppresses TNF-induced NF-kappaB activation through inhibition of IkappaB kinases
    • Oka S, Kamata H, Kamata K, Yagisawa H, Hirata H. N-acetylcysteine suppresses TNF-induced NF-kappaB activation through inhibition of IkappaB kinases. FEBS Lett 2000;472:196-202.
    • (2000) FEBS Lett , vol.472 , pp. 196-202
    • Oka, S.1    Kamata, H.2    Kamata, K.3    Yagisawa, H.4    Hirata, H.5
  • 7
    • 0034949455 scopus 로고    scopus 로고
    • Cecal ligation and puncture as a model of sepsis in the rat: Influence of the puncture size on mortality, bacteremia, endotoxemia and tumor necrosis factor alpha levels
    • Otero-Antón E, González-Quintela A, López-Soto A, López-Ben S, Llovo J, Pérez LF. Cecal ligation and puncture as a model of sepsis in the rat: influence of the puncture size on mortality, bacteremia, endotoxemia and tumor necrosis factor alpha levels. Eur Surg Res 2001;33:77-9.
    • (2001) Eur Surg Res , vol.33 , pp. 77-79
    • Otero-Antón, E.1    González-Quintela, A.2    López-Soto, A.3    López-Ben, S.4    Llovo, J.5    Pérez, L.F.6
  • 9
    • 84855689954 scopus 로고    scopus 로고
    • Sepsis fzyopatolojisinde güncel kavramlar
    • In: Köksal İ, Çakar N, Arman D, editors, Ankara: Bilimsel Ti{dotless}p Yayi{dotless}nevi
    • Kansu E. Sepsis fzyopatolojisinde güncel kavramlar. In: Köksal İ, Çakar N, Arman D, editors. Yoǧun baki{dotless}m enfeksiyonlari{dotless}. Ankara: Bilimsel Ti{dotless}p Yayi{dotless}nevi; 2005. p. 381-93.
    • (2005) Yoǧun Baki{dotless}m Enfeksiyonlari{dotless} , pp. 381-393
    • Kansu, E.1
  • 10
    • 1842478879 scopus 로고    scopus 로고
    • Is there a place for N-acetylcysteine in the treatment of septic shock?
    • Del Sorbo L, Zhang H. Is there a place for N-acetylcysteine in the treatment of septic shock? Crit Care 2004;8:93-5.
    • (2004) Crit Care , vol.8 , pp. 93-95
    • del Sorbo, L.1    Zhang, H.2
  • 11
    • 67650685608 scopus 로고    scopus 로고
    • N-acetyl- cysteine improves group B streptococcus clearance in a rat model of chronic ethanol ingestion
    • Tang SM, Gabelaia L, Gauthier TW, Brown LA. N-acetyl- cysteine improves group B streptococcus clearance in a rat model of chronic ethanol ingestion. Alcohol Clin Exp Res 2009;33:1197-201.
    • (2009) Alcohol Clin Exp Res , vol.33 , pp. 1197-1201
    • Tang, S.M.1    Gabelaia, L.2    Gauthier, T.W.3    Brown, L.A.4
  • 12
    • 33749528921 scopus 로고    scopus 로고
    • Post-treatment with N-acetylcysteine ameliorates endotoxin shock-induced organ damage in conscious rats
    • Hsu BG, Lee RP, Yang FL, Harn HJ, Chen HI. Post-treatment with N-acetylcysteine ameliorates endotoxin shock-induced organ damage in conscious rats. Life Sci 2006;79:2010-6.
    • (2006) Life Sci , vol.79 , pp. 2010-2016
    • Hsu, B.G.1    Lee, R.P.2    Yang, F.L.3    Harn, H.J.4    Chen, H.I.5
  • 13
    • 0036175071 scopus 로고    scopus 로고
    • Glutathione and N-acetylcysteine in the prevention of free-radical damage in the initial phase of septic shock
    • Abstract
    • Ortolani O, Conti A, De Gaudio AR, Moraldi E, Novelli GP. Glutathione and N-acetylcysteine in the prevention of free-radical damage in the initial phase of septic shock. Recenti Prog Med 2002;93:125-9. [Abstract]
    • (2002) Recenti Prog Med , vol.93 , pp. 125-129
    • Ortolani, O.1    Conti, A.2    de Gaudio, A.R.3    Moraldi, E.4    Novelli, G.P.5
  • 14
    • 10744230633 scopus 로고    scopus 로고
    • Systemic, pulmonary, and hepatosplanchnic effects of N-acetylcysteine during long-term porcine endotoxemia
    • Vassilev D, Hauser B, Bracht H, Iványi Z, Schoaff M, Asfar P, et al. Systemic, pulmonary, and hepatosplanchnic effects of N-acetylcysteine during long-term porcine endotoxemia. Crit Care Med 2004;32:525-32.
    • (2004) Crit Care Med , vol.32 , pp. 525-532
    • Vassilev, D.1    Hauser, B.2    Bracht, H.3    Iványi, Z.4    Schoaff, M.5    Asfar, P.6
  • 15
    • 0141504202 scopus 로고    scopus 로고
    • N-acetylcysteine protects mice from lethal endotoxemia by regulating the redox state of immune cells
    • Victor VM, Rocha M, De la Fuente M. N-acetylcysteine protects mice from lethal endotoxemia by regulating the redox state of immune cells. Free Radic Res 2003;37:919-29.
    • (2003) Free Radic Res , vol.37 , pp. 919-929
    • Victor, V.M.1    Rocha, M.2    de la Fuente, M.3
  • 16
    • 33746876627 scopus 로고    scopus 로고
    • N-acetylcysteine ameliorates methotrexate-induced oxidative liver damage in rats
    • Cetinkaya A, Bulbuloglu E, Kurutas EB, Kantarceken B. N-acetylcysteine ameliorates methotrexate-induced oxidative liver damage in rats. Med Sci Monit 2006;12:BR274-BR278.
    • (2006) Med Sci Monit , vol.12
    • Cetinkaya, A.1    Bulbuloglu, E.2    Kurutas, E.B.3    Kantarceken, B.4
  • 17
    • 40149102006 scopus 로고    scopus 로고
    • Silymarin, the antioxidant component of Silybum marianum, prevents sepsis-induced acute lung and brain injury
    • Toklu HZ, Tunali Akbay T, Velioglu-Ogunc A, Ercan F, Ge-dik N, Keyer-Uysal M, et al. Silymarin, the antioxidant component of Silybum marianum, prevents sepsis-induced acute lung and brain injury. J Surg Res 2008;145:214-22.
    • (2008) J Surg Res , vol.145 , pp. 214-222
    • Toklu, H.Z.1    Tunali Akbay, T.2    Velioglu-Ogunc, A.3    Ercan, F.4    Ge-Dik, N.5    Keyer-Uysal, M.6
  • 18
    • 0038113408 scopus 로고    scopus 로고
    • The protective effect of N-acetylcysteine on apoptotic lung injury in cecal ligation and puncture-induced sepsis model
    • Ozdulger A, Cinel I, Koksel O, Cinel L, Avlan D, Unlu A, et al. The protective effect of N-acetylcysteine on apoptotic lung injury in cecal ligation and puncture-induced sepsis model. Shock 2003;19:366-72.
    • (2003) Shock , vol.19 , pp. 366-372
    • Ozdulger, A.1    Cinel, I.2    Koksel, O.3    Cinel, L.4    Avlan, D.5    Unlu, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.