The evolving spectrum of pulmonary disease in responders to the World Trade Center tragedy

American Journal of Industrial Medicine

Volumn 54, Issue 9, 2011, Pages 649-660

  Guidotti, Tee L ^a   Prezant, David ^b   De La Hoz, Rafael E ^c   Miller, Albert ^d  

^a Medical Advisory Services A Division of The NMAS Group   (United States)

^b Government of New york   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^d CITY UNIVERSITY OF NEW YORK   (United States)

Author keywords

Bronchiolitis obliterans; Constrictive bronchiolitis; Dust; FEV1; Inhalation toxicology; Interaction; Interstitial lung disease; Prognosis; Respiratory impairment; Starling resistor; Vital capacity; World Trade Center

Indexed keywords

CALCIUM CARBONATE;

ADULT; BRONCHIOLITIS; CHRONIC OBSTRUCTIVE LUNG DISEASE; DUST; FIRE FIGHTER; HUMAN; INTERSTITIAL LUNG DISEASE; LUNG DISEASE; LUNG FUNCTION TEST; MASS DISASTER; OCCUPATIONAL EXPOSURE; PARTICLE SIZE; PATHOPHYSIOLOGY; POLICE; RESCUE PERSONNEL; REVIEW; STATISTICS; SURVIVOR; TERRORISM; UNITED STATES;

ADULT; BRONCHIOLITIS; CALCIUM CARBONATE; DUST; EMERGENCY RESPONDERS; FIREFIGHTERS; HUMANS; LUNG DISEASES; LUNG DISEASES, INTERSTITIAL; MASS CASUALTY INCIDENTS; NEW YORK CITY; OCCUPATIONAL EXPOSURE; PARTICLE SIZE; POLICE; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RESPIRATORY FUNCTION TESTS; SEPTEMBER 11 TERRORIST ATTACKS; SURVIVORS;

EID: 80051713688     PISSN: 02713586     EISSN: 10970274     Source Type: Journal    
DOI: 10.1002/ajim.20987     Document Type: Review

References (79)

1. Aldrich TK, Gustave J, Hall CB, Cohen HW, Webber MP, Zeig-Owens R, Cosenza K, Christodoulou V, Glass L, Al-Othman F, Weiden MD, Kelly KJ, Prezant DJ. 2010. Lung function in rescue workers at the World Trade Center after seven years. N Eng J Med 362(14): 1263-1272.
2. Banauch GI, Alleyne D, Sanchez R, Olender K, Cohen HW, Weiden M, Kelly KJ, Prezant DJ. 2003. Persistent hyperreactivity and reactive airway dysfunction in firefighters at the World Trade Center. Am J Resp Crit Care Med 168(1): 54-62.
3. Banauch GI, Dhala A, Prezant DJ. 2005. Pulmonary disease in rescue workers at the World Trade Center site. Curr Opinion Pulm Med 11(2): 160-168.
4. Banauch GI, Hall C, Cohen HW, Weiden M, Aldrich TK, Christodoulou V, Arcentales N, Kelly KJ, Prezant DJ. 2006. Pulmonary function after exposure to the World Trade Center collapse in NewYork City Fire Department. Am J Resp Crit Care Med 174(3): 312-319.
5. Bowers B, Hasni S, Gruber BL. 2010. Sarcoidosis in World Trade Center rescue workers presenting with rheumatologic manifestations. J Clin Rheumatol 16(1): 26-27.
6. Brackbill R, Thorpe L, DiGrande L, Perrin M, Sapp J, Wu D. 2006. Surveillance for World Trade Center heath effects among survivors of collapsed and damaged buildings. MMWR Surveill Summ 55(2): 1-18.
7. Brackbill RM, Hadler JL, DiGrande L, Ekenga CC, Farfel MR, Friedman S, Perlman SE, Stellman SD, Walker DJ, Wu D, Yu S, Thorpe LE. 2009. Asthma and posttraumatic stress symptoms 5 to 6 years following exposure to the World Trade Center terrorist attack. JAMA 302(5): 502-516.
8. Brooks SM, Weiss MA, Bernstein IL. 1985. Reactive airways dysfunction syndrome. Chest 88: 376-384.
9. Buyantseva LV, Tulchinsky M, Kapalka GM, Chinchilli VM, Qian Z, Gillio R, Roberts A, Bascom R. 2007. Evolution of lower respiratory symptoms in New York police officers after 9/11: A prospective longitudinal study. J Occup. Environ Med 49: 310-317.
10. Centers for Disease Control Prevention. 2002. Self-reported increase in asthma severity after the September 11 attacks on the World Trade Center-Manhattan, New York, 2001. Morb Mortal Wkly Rep 51: 781-784.
11. Centers for Disease Control Prevention. 2004. Physical health status of World Trade Center rescue and recovery workers & volunteers-New York City July 2002-August 2004. Morb Mortal Wkly Rep 53: 807-812.
12. Chen LC, Thurston G. 2001. World Trade Center cough. Lancet 360(Suppl): s37-s38.
13. Colby TV. 1998. Bronchiolitis. Pathologic considerations. Am J Clin Pathol 109(1): 101-109.
14. Crowley LE, Herbert R, Moline JM, Wallenstein S, Shukla G, Schechter C, Skloot GS, Udasin I, Luft BJ, Harrison D, Shapiro M, Wong K, Sacks HS, Landrigan PJ, Teirstein AS. 2010. "Sarcoid like" granulomatous pulmonary disease in World Trade Center disaster responders. Am J Ind Med [Epub ahead of print].
15. de la Hoz RE. 2010. Occupational asthma and lower airway disease in former World Trade Center workers and volunteers. Curr Allergy Asthma Rep 10: 287-294.
16. de la Hoz RE, Shohet MR, Chasan R, Bienenfeld LA, Afilaka AA, Levin SM, Herbert R. 2008a. Occupational toxicant inhalation injury: The World Trade Center (WTC) experience. Int Arch Occup Environ Health 81: 479-485.
17. de la Hoz RE, Christie J, Teamer J, Bienenfeld LA, Afilaka AA, Crane M, Levin SM, Herbert R. 2008b. Reflux symptoms and disorders and pulmonary disease in former World Trade Center rescue and recovery workers and volunteers. J Occup Environ Med 50: 1351-1354.
18. de la Hoz RE, Hill S, Chasan R, Bienenfeld LA, Afilaka AA, Wilk-Rivard E, Herbert R. 2008c. Health care and social issues of immigrant rescue and recovery workers at the World Trade Center site. J Occup Environ Med 50: 1329-1334.
19. de la Hoz RE, Shohet MR, Wisnivesky JP, Bienenfeld LA, Afilaka AA, Herbert R. 2009. Atopy and upper and lower airway disease among former World Trade Center workers and volunteers. J Occup Environ Med 51: 992-995.
20. de la Hoz RE, Shohet MR, Cohen JM. 2010. Occupational rhinosinusitis and upper airway disease: The World Trade Center experience. Curr Allergy Asthma Rep 10: 77-83.
21. Delfino Rj, Sioutas C, Malik S. 2005. Potential of ultrafine particles in associations between airborne particle mass and cardiovascular health. Environ Health Perspect 113: 934-946.
22. El-Zammar O, Rosenbaum P, Katzenstein AL. 2009. Proliferative activity in fibrosis lung diseases: A comparative study of Ki-67 immunoreactivity in diffuse alveolar damage, bronchiolitis obliterans-organizing pneumonia, and usual interstitial pneumonia. Hum Pathol 40(8): 1182-1188.
23. Epler GR, Colby TV. 1983. The spectrum of bronchiolitis obliterans. Chest 83: 161-162.
24. Fournier M, Couvelard A, Mai H, Groussard O. 2006. Non-transplant related constrictive bronchiolitis in adults. Rev Malad Resp 23(3): S57-S66.
25. Friedman S, Cone J, Eros-Sarnyai M, Prezant D, Szeinuk J, Clark N, Milek D, Levin S, Gillio R. 2008. Clinical guidelines for adults exposed to World Trade Center Disaster (Respiratory and Mental Health). City Health Inf (NYC Dep Health Mental Hyg) 27(6): 41-54.
26. Gavett SH. 2006. Physical characteristics and health effects of aerosols from collapsed buildings. J Aerosol Res 19(1): 84-91.
27. Gavett SH, Haykal-Coates N, Highfill JW, Ledbetter AD, Chen LC, Cohen MD, Harkema JR, Wagner JG, Costa DL. 2003. World Trade Center fine particulate matter causes respiratory tract hyperresponsiveness in mice. Environ Health Perspect 11(7): 981-991.
28. Guidotti TL. 1995. Toxic pulmonary edema. Chapter 4. In: Cordasco E, Demeter S, Zenz C, editors. Environmental lung disease. New York: Van Nostrand Reinhold, pp. 85-114.
29. Guidotti TL. 2007. Respiratory tract irritants. Chapter 33. In: Rom W, Markowitz S, editors. Environmental and occupational medicine. 4th edition. Philadelphia: Lippincott, pp. 543-555.
30. Herbert R, Moline J, Skloot G, Metzger K, Baron S, Luft B. 2006. The World Trade Center disaster and health of workers; Five year assessment of a unique medical screening program. Environ Health Perspect 114: 1853-1858.
31. Herbstman J, Schwab M. 2005. Respiratory effects of inhalation exposure among workers during the clean-up effort at the WTC disaster site. Environ Res 99: 85-92.
32. Howard P. 1971. The airway as Starling resistor. Bull Pathophysiol Resp (Nancy) 7(2): 467-474.
33. Hyatt RE, Cowl CT, Bjoraker JA, Scanlon PD. 2009. Conditions associated with an abnormal nonspecific pattern of pulmonary function tests. Chest 135(2): 419-424.
34. Izbicki G, Chavko R, Banauch GI, Weiden MD, Berger KI, Aldrich TK, Hall C, Kelly KJ, Prezant DJ. 2007. World Trade Center "sarcoid-like" granulomatous pulmonary disease in New York City Fire Department rescue workers. Chest 131(5): 1414-1423.
35. Jordan HT, Cone J, Thorpe L. 2008. Sarcoidosis diagnosed after September 11, 2001 among persons exposed to 9/11/2001 World Trade Center disaster. Presented at the 136th APHA Annual Meeting and Expo October 25-29, 2008. San Diego, CA. Accessed February 2011.
36. Kelly KJ, Niles J, Corrigan M, McLaughlin MT, Carroll S, Al-Othman F, Prezant DJ. 2007. FDNY health WTC effects-A six year assessment. New York: FDNY. Accessed February 2011.
37. King T. 1989. Bronchiolitis obliterans. Lung 167: 69-93.
38. Konen E, Gutierrez C, Chaparro C. 2004. Bronchiolitis obliterans syndrome in lung transplant recipients: Can thin-section CT findings predict disease before its clinical appearance? Radiology 231: 467-473.
39. Kreiss K, Gomaa A, Kullman G, Fedan K, Simoes EJ, Enright PL. 2002. Clinical bronchiolitis obliterans in workers at a microwave-popcorn plant. N Engl J Med 347: 330-338.
40. Landrigan PJ, Lioy PJ, Thurston G, Berkowitz G, Chen LC, Chillrud SN, Gavett SH, Georgopolous PG, Geyh AS, Levin S, Perera F, Rappaport SM, Small C, NIEHS World Trade Center Working Group. 2004. Health and environmental consequences of the World Trade Center disaster. Environ Health Perspect 112(6): 731-739.
41. Lioy PJ, Weisel CP, Millette JR, Eisenreich S, Vallero D, Offenberg J, Buckley B, Turpin B, Zhong M, Cohen MD, Prophete C, Yang I, Stiles R, Chee G, Johnson W, Porcja R, Alimokhtari S, Hale RC, Weschler C, Chen LC. 2002. Characterization of the dust/smoke aerosol that settled east of the World Trade Center (WTC) in lower Manhattan after the collapse of the WTC 11 September 2001. Environ Health Perspect 110(7): 703-714.
42. Lopez-Muniz R, Stephens NL, Bromberger-Barnea B, Permutt S, Riley RL. 1968. Critical closure of pulmonary vessels analyzed in terms of Starling resistor model. J Appl Physiol 24(5): 625-635.
43. Lowers HA, Meeker GP, Lioy PJ, Lippmann M. 2010. Summary of the development of a signature for detection of residual dust from the collapse of the World Trade Center buildings. J Expo Sci Environ Epidemiol 20(4): 393-394.
44. Mann JM, Sha KK, Kline G, Breuer F-U, Miller A. 2005. World Trade Center dyspnea: Bronchiolitis obliterans with functional improvement: A case report. Am J Ind Med 48: 225-229.
45. Markopoulou KD, Cool CD, Elliot TL, Lynch DA, Newell JD, Jr., Hale VA, Brown KK, Schwartz MI, Tuder RM. 2002. Obliterative bronchiolitis: Varying presentations and clinicopathological correlation. Euro Resp J 19: 20-30.
46. McGee JK, Chen LC, Cohen MD, Chee GR, Prophete CM, Haykal-Coates CM, Wasson SJ, Conner TL, Costa DL, Gavett SH. 2003. Chemical analysis of World Trade Center fine particulate matter for use in toxicologic assessment. Environ Health Perspect 111(7): 972-980.
47. Mendelson DS, Roggeveen M, Levin SM. 2007. Air trapping detected on end-expiratory high-resolution computed tomography in symptomatic World Trade Center rescue and recovery workers. J Occup Environ Med 49: 840-845.
48. Meyers JL, Colby TV. 1993. Pathologic manifestations of bronchiolitis, constrictive bronchiolitis, cryptogenic organizing pneumonia and diffuse panbronchiolitis. Clin Chest Med 14: 611-621.
49. Miller A. 2007. Sarcoidosis, firefighters sarcoidosis, and World Trade Center "sarcoid-like" granulomatous pulmonary disease. Chest 132(6): 2053.
50. Oberdörster G. 2001. Pulmonary effects of inhaled ultrafine particles. Int Arch Occup Environ Health 74: 1-8.
51. Oppenheimer BW, Goldring RM, Herberg ME, Hofer IS, Reyfman PA, Liautaud S, Rom WN, Reibman J, Berger KI. 2007. Distal airway function in symptomatic subjects with normal spirometry following World Trade Center dust exposure. Chest 132: 1275-1282.
52. Parambil JG, Yi ES, Ryu JH. 2009. Obstructive bronchiolar disease identified by CT in the nontransplant population: Analysis of 29 consecutive cases. Respirology 14(3): 443-448.
53. Parmet AJ, Von Essen S. 2002. Rapidly progressive, fixed airway obstructive disease in popcorn workers: A new occupational pulmonary illness? J Occup Environ Med 44: 216-218.
54. Piippo-Savolainen E, Remes S, Kannisto S, Korhonen K, Korppi M. 2006. Early predictors for adult asthma and lung function abnormalities in infants hospitalized for bronchiolitis: A prospective 18- to 20-year follow-up. Allergy Asthma Proc 27: 341-349.
55. Prezant DJ, Weiden M, Banauch GI, McGuinness G, Rom WN, Aldrich TK, Kelly KJ. 2002. Cough and bronchial responsiveness in firefighters at the World Trade Center site. N Engl J Med 347: 806-815.
56. Prezant DJ, Levine S, Kelly KJ, Aldrich TK. 2008. Upper and lower respiratory diseases after occupational and environmental disasters. Mt Sinai Med J 75(2): 89-100.
57. Reibman J. 2003. Respiratory health of residents near the former World Trade Center: The WTC Residents Respiratory Health Survey [Abstract]. Am J Respir Crit Care Med 167: A335.
58. Rom WN, Weiden M, Garcia R. 2002. Acute eosinophilic pneumonia in a New-York city firefighter exposed to World Trade Center dust. Am J Respir Crit Care Med 166: 797-800.
59. Rom WN, Reibman J, Rogers L, Weiden MD, Oppenheimer B, Berger K, Goldring R, Harrison D, Prezant D. 2010. Emerging exposures and respiratory health: World Trade Center dust. Proc Am Thorac Soc 7(2): 142-145.
60. Rossi SE, Franquet T, Volpacchio M, Giménez A, Aguilar G. 2005. Tree-in-bud pattern at thin-section CT of the lungs: Radiologic-pathologic overview. Radiographics 25: 789-801.
61. Ryu JH, Myers J, Swenson SJ. 2003. Bronchiolar disorders. Am Rev Resp Crit Care Med 168(11): 1277-1292.
62. Safirstein BH, Klukowicz A, Miller R, Teirstein A. 2003. Granulomatous pneumonitis following exposure to the World Trade Center collapse. Chest 123: 301-304.
63. Salzman SH, Moosavy FM, Miskoff JA, Friedmann P, Fried G, Rosen MJ. 2004. Early respiratory abnormalities in emergency services police officers at the World Trade Center site. J Occup Environ Med 46: 113-122.
64. Sarnat JA, Koutrakis P, Suh HH. 2000. Assessing the relationship between personal particulate and gaseous exposures of senior citizens living in Baltimore, MD. J Air Waste Manage Assoc 50: 1184-1198.
65. Sarnat JA, Schwartz J, Catalano PJ, Suh HH. 2001. Gaseous pollutants in particulate matter epidemiology: Confounders or surrogates? Environ Health Perspect 109: 1053-1061.
66. Schacter EN. 2002. Popcorn workers' lung. N Engl J Med 347(5): 360-361.
67. Schlesinger C, Meyer CA, Veeraraghavan S, Koss MN. 1998. Constrictive (obliterative) bronchiolitis: Diagnosis, etiology, and a critical review of the literature. Ann Diagn Pathol 2(5): 321-334.
68. Skloot G, Goldman M, Fischler D, Goldman C, Schechter C, Levin S, Teirstein A. 2004. Respiratory symptoms and physiologic assessment of ironworkers at the World Trade Center disaster site. Chest 25: 1248-1255.
69. Szema AM, Khedkar M, Maloney PF, Takach PA, Nickels MS, Patel H, Modugno F, Tso AY, Lin DH. 2004. Clinical deterioration in pediatric asthmatic patients after September 11, 2001. J Allergy Clin Immunol 113: 420-426.
70. Tapp L, Baron S, Bernard B, Driscoll R, Mueller C, Wallingford K. 2005. Physical and mental health symptoms among NYC Transit Workers seven and one half months after the WTC attacks. Am J Ind Med 47: 475-483.
71. Thurlbeck WM. 1982. The pathology of small airways in chronic airflow limitation. Eur J Respir Dis 121(Suppl): 9-18.
72. Visscher DW, Myers JL. 2006. Bronchiolitis: The pathologist's perspective. Proc Am Thoracic Soc 3(1): 41-47.
73. Walters EH, Reid DW, Johns DP, Ward C. 2007. Nonpharmacological and pharmacological interventions to prevent or reduce airway remodelling. Eur Respir J 30: 574-588.
74. Wanger J, Clausen JL, Coates A, Pedersen OF, Brusasco V, Burgos F, Casaburi R, Crapo R, Enright P, van der Grinten CPM, Gustaffson P, Hankinson J, Jensen R, Johnson D, MacIntyre N, McKay R, Miller MR, Navajas D, Pellegrino R, Viegi G. 2005. Standardisation of the measurement of lung volumes. Euro Resp J 26(3): 511-522.
75. Webber MP, Gustave J, Lee R, Niles JK, Kelly K, Cohen HW, Prezant DJ. 2009. Trends in respiratory symptoms of firefighters exposed to the World Trade Center disaster 2001-2005. Environ Health Perspect 117(6): 975-980.
76. Weiden MD, Ferrier N, Nolan A, Rom WN, Comfort A, Gustave J, Zeig-Owens R, Zheng S, Goldring RM, Berger KI, Cosenza K, Lee R, Webber MP, Kelly KJ, Aldrich TK, Prezant DJ. 2010. Obstructive airways disease with air trapping among firefighters exposed to World Trade Center dust. Chest 137(3): 566-574.
77. Wheeler K, McKelvey, Thorpe L, Perrin M, Cone J, Kass D, Farfel M, Thomas PA, Brackbill RM. 2007. Asthma diagnosed after September 11, 2001 among rescue and recovery workers: Findings from the World Trade Center registry. Environ Health Perspect 115(11): 1584-1590.
78. Wright JL. 2001. Diseases of the small airways. Lung 179(6): 375-396.
79. Wu MX, Gordon RE, Herbert R, Padilla M, Moline J, Mendelson D, Litle V, Travis WD, Gil J. 2010. Case report: Lung disease in World Trade Center Responders exposed to dust and smoke: Carbon nanotubules found in the lungs of World Trade Center patients and dust samples. Environ Health Perspect 118(4): 499-504.