One-step, nonenzymatic synthesis of O-acetyl-ADP-ribose and analogues from NAD and carboxylates

Journal of Organic Chemistry

Volumn 76, Issue 16, 2011, Pages 6465-6474

  Szczepankiewicz, Bruce G ^a   Koppetsch, Karsten J ^a   Perni, Robert B ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYLIC ESTERS; DEACETYLATION; NICOTINAMIDE ADENINE DINUCLEOTIDES; NON-AQUEOUS; NON-ENZYMATIC; SODIUM ACETATE;

ACETIC ACID; ACETYLATION; AMIDES; CARBOXYLATION; CARBOXYLIC ACIDS; SODIUM;

BIOSYNTHESIS;

ACETIC ACID; ADENOSINE DIPHOSPHATE RIBOSE ACETATE; BUFFER; CARBOXYLIC ACID; ESTER DERIVATIVE; NICOTINAMIDE ADENINE DINUCLEOTIDE; SIRTUIN;

ARTICLE; CHEMICAL REACTION; DEACETYLATION; ENZYME MECHANISM; ENZYME SYNTHESIS; SYNTHESIS;

AMINO ACID SEQUENCE; CARBOXYLIC ACIDS; HISTONE DEACETYLASES; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; NAD; O-ACETYL-ADP-RIBOSE; SIRTUIN 2; SIRTUINS;

EID: 80051711999     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo2008466     Document Type: Article

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