Cholesterol- and sphingolipid-rich microdomains are essential for microtubule-based membrane protrusions induced by Clostridium difficile transferase (CDT)

Journal of Biological Chemistry

Volumn 286, Issue 33, 2011, Pages 29356-29365

  Schwan, Carsten ^a   Nölke, Thilo ^a   Kruppke, Anna S ^a   Schubert, Daniel M ^a   Lang, Alexander E ^a   Aktories, Klaus ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN CYTOSKELETON; BACTERIAL ADHESION; BENZYL ALCOHOL; CHOLERA TOXIN; CLOSTRIDIUM DIFFICILE; CONCENTRATION-DEPENDENT; DIFFICILE STRAIN; HUMAN COLON; LIPID RAFT; MEMBRANE FLUIDITY; MEMBRANE LIPIDS; MICRO-DOMAINS; MICROTUBULES; MYRIOCIN; SPHINGOLIPIDS; SPHINGOMYELINASE; TARGET CELLS;

CHOLESTEROL; CLOSTRIDIUM; ENZYME INHIBITION; LIPIDS; PROTEINS; TOXIC MATERIALS;

MEMBRANES;

ACTIN; BENZYL ALCOHOL; CHOLERA TOXIN B SUBUNIT; CHOLESTEROL; CLOSTRIDIUM DIFFICILE TOXIN A; CLOSTRIDIUM DIFFICILE TOXIN B; FLOTILLIN 2; GANGLIOSIDE GM1; MEMBRANE LIPID; METHYL BETA CYCLODEXTRIN; NYSTATIN; SPHINGOLIPID; SPHINGOMYELIN PHOSPHODIESTERASE; THERMOZYMOCIDIN;

ARTICLE; CELL MEMBRANE; COLON ADENOCARCINOMA; CONCENTRATION RESPONSE; CONTROLLED STUDY; HUMAN; HUMAN CELL; LIPID COMPOSITION; MEMBRANE FLUIDITY; MICROTUBULE; NONHUMAN; PRIORITY JOURNAL;

ANTI-BACTERIAL AGENTS; ANTIFUNGAL AGENTS; BACTERIAL ADHESION; BACTERIAL TOXINS; BETA-CYCLODEXTRINS; CACO-2 CELLS; CHOLESTEROL; CLOSTRIDIUM DIFFICILE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENTEROCOLITIS, PSEUDOMEMBRANOUS; FATTY ACIDS, MONOUNSATURATED; HUMANS; MEMBRANE MICRODOMAINS; MICROTUBULES; NYSTATIN; SPHINGOLIPIDS; SPHINGOMYELIN PHOSPHODIESTERASE;

BACTERIA (MICROORGANISMS); CLOSTRIDIUM DIFFICILE;

EID: 80051692343     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.261925     Document Type: Article

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