BARD1 expression predicts outcome in colon cancer

Clinical Cancer Research

Volumn 17, Issue 16, 2011, Pages 5451-5462

  Sporn, Judith C ^a   Hothorn, Torsten ^b   Jung, Barbara ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; BRCA1 ASSOCIATED RING DOMAIN PROTEIN 1; ISOPROTEIN; MESSENGER RNA;

ARTICLE; CANCER INHIBITION; CANCER PATIENT; CANCER TISSUE; COLON CANCER; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN TISSUE; NUCLEOTIDE SEQUENCE; OUTCOME ASSESSMENT; PREDICTION; PRIMARY TUMOR; PRIORITY JOURNAL; PROGNOSIS; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN VARIANT; RISK ASSESSMENT;

ADULT; AGED; ALTERNATIVE SPLICING; ANTIMETABOLITES, ANTINEOPLASTIC; BLOTTING, WESTERN; COHORT STUDIES; COLON; COLONIC NEOPLASMS; FEMALE; FLUOROURACIL; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PROGNOSIS; PROTEIN ISOFORMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SURVIVAL ANALYSIS; TREATMENT OUTCOME; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN-PROTEIN LIGASES;

EID: 80051690788     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-11-0263     Document Type: Article

References (29)

1. Miki Y, Swensen J, Shattuck-Eidens D, Futreal PA, Harshman K, Tavtigian S, et al. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 1994;266:66-71. (Pubitemid 24345325)
2. Kadouri L, Hubert A, Rotenberg Y, Hamburger T, Sagi M, Nechushtan C, et al. Cancer risks in carriers of the BRCA1/2 Ashkenazi founder mutations. J Med Genet 2007;44:467-471 (Pubitemid 47056875)
3. Wu LC, Wang ZW, Tsan JT, Spillman MA, Phung A, Xu XL, et al. Identification of a RING protein that can interact in vivo with the BRCA1 gene product. Nat Genet 1996;14:430-440 (Pubitemid 26414587)
4. Shakya R, Szabolcs M, McCarthy E, Ospina E, Basso K, Nandula S, et al. The basal-like mammary carcinomas induced by Brca1 or Bard1 inactivation implicate the BRCA1/BARD1 heterodimer in tumor suppression. Proc Natl Acad Sci U S A 2008;105:7040-7045 (Pubitemid 351754526)
5. De Brakeleer S, De Grève J, Loris R, Janin N, Lissens W, Sermijn E, et al. Cancer predisposing missense and protein truncating BARD1 mutations in non-BRCA1 or BRCA2 breast cancer families. Hum Mutat 2010;31:E1175-E1185
6. Karppinen SM, Heikkinen K, Rapakko K, Winqvist R. Mutation screening of the BARD1 gene: evidence for involvement of the Cys557Ser allele in hereditary susceptibility to breast cancer. J Med Genet 2004;41:e114.
7. Thai TH, Du F, Tsan JT, Jin Y, Phung A, Spillman MA, et al. Mutations in the BRCA1-associated RING domain (BARD1) gene in primary breast, ovarian and uterine cancers. Hum Mol Genet 1998;7:195-202. (Pubitemid 28048534)
8. Feki A, Jefford CE, Jefford CE, Durand P, Harb J, Lucas H, et al. BARD1 expression during spermatogenesis is associated with apoptosis and hormonally regulated. Biol Reprod 2004;71:1614-1624 (Pubitemid 39403258)
9. Feki A, Jefford CE, Berardi P, Wu JY, Cartier L, Krause KH, et al. BARD1 induces apoptosis by catalysing phosphorylation of p53 by DNA-damage response kinase. Oncogene 2005;24:3726-3736 (Pubitemid 40826872)
10. Tsuzuki M, Wu W, Nishikawa H, Hayami R, Oyake D, Yabuki Y, et al. A truncated splice variant of human BARD1 that lacks the RING finger and ankyrin repeats. Cancer Lett 2006;233:108-116 (Pubitemid 43214568)
11. Li L, Cohen M, Wu J, Sow MH, Nikolic B, Bischof P, et al. Identification of BARD1 splice-isoforms involved in human trophoblast invasion. Int J Biochem Cell Biol 2007;39:1659-1672 (Pubitemid 47090213)
12. Li L, Ryser S, Dizin E, Pils D, Krainer M, Jefford CE, et al. Oncogenic BARD1 isoforms expressed in gynecological cancers. Cancer Res 2007;67:11876-11885
13. Lombardi G, Falaschi E, Di Cristofano C, Naccarato AG, Sensi E, Aretini P, et al. Identification of novel alternatively spliced BRCA1-associated RING domain (BARD1) messenger RNAs in human peripheral blood lymphocytes and in sporadic breast cancer tissues. Genes Chromosomes Cancer 2007;46:791-795 (Pubitemid 47106182)
14. Rozen S, Skaletsky HJ. Primer3 on the WWW for general users and for biologist programmers. In:Krawetz S, Misener S, editors. Bioinformatics methods and protocols: methods in molecular biology. Totowa, NJ: Humana Press; 2000. p. 365-386
15. Carethers JM, Smith EJ, Behling CA, Nguyen L, Tajima A, Doctolero RT, et al. Use of 5-fluorouracil and survival in patients with microsatellite-unstable colorectal cancer. Gastroenterology 2004;126:394-401. (Pubitemid 38182296)
16. Hothorn T, Bretz F, Westfall P. Simultaneous inference in general parametric models. Biom J 2008;50:346-363
17. Hothorn T, Hornik K, Zeileis A. Unbiased recursive partitioning: a conditional inference framework. J Comput Graphical Stat 2006;15:651-674 (Pubitemid 44554201)
18. Owzar K. Alternate statistical tools and limitations in genetic marker association studies in single-arm drug cancer trials. J Clin Oncol 2008;26:1400-1401
19. Zeileis A, Meyer D, Hornik K. Residual-based shadings for visualizing (conditional) independence. J Comput Graphical Stat 2007;16:507-525
20. R Development Core Team (2011). R: a language and environment for statistical computing. R foundation for statistical computing. Vienna, Austria. Available from:http://www.R-project.org/.
21. Therneau T, Lumley T. survival: survival analysis, including penalised likelihood. 2011. Available from:http://CRAN.R-project.org/package=survival.
22. Hothorn T, Hornik K, Strobl C, Zeileis A. Party: a laboratory for recursive partytioning. Available from:http://CRAN.R-project.org/package=party.
23. Hothorn T, Bretz F, Westfall P, Heiberger RM, Schuetzenmeister A. Multcomp: simultaneous inference in general parametric models. Available from:http://CRAN.R-project.org/package=multcomp.
24. Erickson HS, Albert PS, Gillespie JW, Wallis BS, Rodriguez-Canales J, Linehan WM, et al. Assessment of normalization strategies for quantitative RT-PCR using microdissected tissue samples. Lab Invest 2007;87:951-962 (Pubitemid 47267819)
25. Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, De Paepe A, et al. Accurate normalization of real-time quantitative RTPCR data by geometric averaging of multiple internal control genes. Genome Biol 2002;3:RESEARCH0034.
26. Jemal A, Siegel R, Xu J, Ward E. Cancer statistics, 2010. CA Cancer J Clin 2010;60:277-300.
27. Brinkman BM. Splice variants as cancer biomarkers. Clin Biochem 2004;37:584-594 (Pubitemid 38845021)
28. Venables JP. Aberrant and alternative splicing in cancer. Cancer Res 2004;64:7647-7654 (Pubitemid 39446889)
29. Sauer MK, Andrulis IL. Identification and characterization of missense alterations in the BRCA1 associated RING domain (BARD1) gene in breast and ovarian cancer. J Med Genet 2005;42:633-638 (Pubitemid 41129035)