Dual inhibition of α/β-hydrolase domain 6 and fatty acid amide hydrolase increases endocannabinoid levels in neurons

Journal of Biological Chemistry

Volumn 286, Issue 33, 2011, Pages 28723-28728

  Marrs, William R ^a   Horne, Eric A ^b   Ortega Gutierrez, Silvia ^c   Cisneros, Jose Antonio ^c   Xu, Cong ^b   Lin, Yi Hsing ^b   Muccioli, Giulio G ^d   Lopez Rodriguez, Maria L ^c   Stella, Nephi ^b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^d UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CANNABINOID RECEPTORS; ENDOCANNABINOID; FATTY ACID AMIDE HYDROLASE; PHARMACOLOGICAL PROFILES; SIDE EFFECT; THERAPEUTIC EFFECTS; THERAPEUTIC POTENTIALS;

AMIDES; CATALYSTS; GLYCEROL; HYDROLASES; HYDROLYSIS; SIGNALING;

FATTY ACIDS;

2 ARACHIDONOYLGLYCEROL; ACYLGLYCEROL LIPASE; ALPHA BETA HYDROLASE DOMAIN 6; ANANDAMIDE; ENDOCANNABINOID; ENZYME INHIBITOR; FATTY ACID AMIDASE; HYDROLASE; UCM 710; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; CONCENTRATION (PARAMETERS); DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; HAPLORHINI; HYDROLYSIS; INTRACELLULAR SIGNALING; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL;

AMIDOHYDROLASES; ANIMALS; ARACHIDONIC ACIDS; CERCOPITHECUS AETHIOPS; COS CELLS; ENDOCANNABINOIDS; ENZYME INHIBITORS; GLYCERIDES; MICE; MONOACYLGLYCEROL LIPASES; NERVE TISSUE PROTEINS; NEURONS; RECEPTORS, CANNABINOID;

EID: 80051679207     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.202853     Document Type: Article

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