Initial fate of prions upon peripheral infection: Half-life, distribution, clearance, and tissue uptake

FASEB Journal

Volumn 25, Issue 8, 2011, Pages 2792-2803

  Urayama, Akihiko ^a   Morales, Rodrigo ^a   Niehoff, Michael L ^b   Banks, William A ^c   Soto, Claudio ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Blood brain barrier; Pharmacokinetics; PrP Sc

Indexed keywords

PRION PROTEIN; SODIUM IODIDE I 125; SODIUM IODIDE I 131;

ARTICLE; BLOOD BRAIN BARRIER; HALF LIFE TIME; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOTOPE LABELING; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRION; PRION DISEASE; PRIORITY JOURNAL; PROTEIN PURIFICATION; TISSUE DISTRIBUTION; WESTERN BLOTTING;

ANIMALS; BIOLOGICAL TRANSPORT, ACTIVE; BRAIN; HALF-LIFE; INJECTIONS, INTRAVENOUS; METABOLIC CLEARANCE RATE; MICE; PRION DISEASES; PROTEIN STABILITY; PRPSC PROTEINS; SCRAPIE; TISSUE DISTRIBUTION;

MUS;

EID: 80051676298     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-180729     Document Type: Article

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