Serum autotaxin measurements in pregnant women: Application for the differentiation of normal pregnancy and pregnancy-induced hypertension

Clinica Chimica Acta

Volumn 412, Issue 21-22, 2011, Pages 1944-1950

  Masuda, Akiko ^a   Fujii, Tomoyuki ^b   Iwasawa, Yuki ^b   Nakamura, Kazuhiro ^a   Ohkawa, Ryunosuke ^a   Igarashi, Koji ^c   Okudaira, Shinichi ^d   Ikeda, Hitoshi ^a,e   Kozuma, Shiro ^b   Aoki, Junken ^d,f   Yatomi, Yutaka ^a,e  

^a UNIVERSITY OF TOKYO HOSPITAL   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c TOSOH CORPORATION   (Japan)

^d TOHOKU UNIVERSITY   (Japan)

^e UNIVERSITY OF TOKYO   (Japan)

^f JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Autotaxin; Lysophosphatidic acid; Lysophospholipase D; Pregnancy; Pregnancy induced hypertension

Indexed keywords

AUTOTAXIN;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE MARKER; ENZYME IMMUNOASSAY; FEMALE; GESTATIONAL AGE; HUMAN; MATERNAL HYPERTENSION; PREDICTIVE VALUE; PREGNANCY; PREMATURE LABOR; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; THIRD TRIMESTER PREGNANCY;

ADULT; AUTOMATION; FEMALE; HUMANS; HYPERTENSION, PREGNANCY-INDUCED; IMMUNOENZYME TECHNIQUES; PHOSPHORIC DIESTER HYDROLASES; PREGNANCY; REPRODUCIBILITY OF RESULTS; ROC CURVE;

EID: 80051673442     PISSN: 00098981     EISSN: 18733492     Source Type: Journal    
DOI: 10.1016/j.cca.2011.06.039     Document Type: Article

References (40)

1. Birgbauer E., Chun J. New developments in the biological functions of lysophospholipids. Cell Mol Life Sci 2006, 63:2695-2701.
2. van Meeteren L., Moolenaar W. Regulation and biological activities of the autotaxin-LPA axis. Prog Lipid Res 2007, 46:145-160.
3. Valentine W., Fujiwara Y., Tsukahara R., Tigyi G. Lysophospholipid signaling: beyond the EDGs. Biochim Biophys Acta 2008, 1780:597-605.
4. Yanagida K., Masago K., Nakanishi H., et al. Identification and characterization of a novel lysophosphatidic acid receptor, p2y5/lPA6. J Biol Chem 2009, 284:17731-17741.
5. Moolenaar W., van Meeteren L., Giepmans B. The ins and outs of lysophosphatidic acid signaling. Bioessays 2004, 26:870-881.
6. Hosogaya S., Yatomi Y., Nakamura K., et al. Measurement of plasma lysophosphatidic acid concentration in healthy subjects: strong correlation with lysophospholipase D activity. Ann Clin Biochem 2008, 45:364-368.
7. Tokumura A., Majima E., Kariya Y., et al. Identification of human plasma lysophospholipase D, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phosphodiesterase. J Biol Chem 2002, 277:39436-39442.
8. Umezu-Goto M., Kishi Y., Taira A., et al. Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production. J Cell Biol 2002, 158:227-233.
9. Stracke M., Krutzsch H., Unsworth E., et al. Identification, purification, and partial sequence analysis of autotaxin, a novel motility-stimulating protein. J Biol Chem 1992, 267:2524-2529.
10. Nakamura K., Takeuchi T., Ohkawa R., et al. Serum lysophospholipase D/autotaxin may be a new nutritional assessment marker: study on prostate cancer patients. Ann Clin Biochem 2007, 44:549-556.
11. Tanaka M., Okudaira S., Kishi Y., et al. Autotaxin stabilizes blood vessels and is required for embryonic vasculature by producing lysophosphatidic acid. J Biol Chem 2006, 281:25822-25830.
12. Lee H., Murata J., Clair T., et al. Cloning, chromosomal localization, and tissue expression of autotaxin from human teratocarcinoma cells. Biochem Biophys Res Commun 1996, 218:714-719.
13. Hama K., Aoki J., Fukaya M., et al. Lysophosphatidic acid and autotaxin stimulate cell motility of neoplastic and non-neoplastic cells through LPA1. J Biol Chem 2004, 279:17634-17639.
14. Kishi Y., Okudaira S., Tanaka M., et al. Autotaxin is overexpressed in glioblastoma multiforme and contributes to cell motility of glioblastoma by converting lysophosphatidylcholine to lysophosphatidic acid. J Biol Chem 2006, 281:17492-17500.
15. van Meeteren L., Ruurs P., Stortelers C., et al. Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development. Mol Cell Biol 2006, 26:5015-5022.
16. Ye X. Lysophospholipid signaling in the function and pathology of the reproductive system. Hum Reprod Update 2008, 14:519-536.
17. Ye X., Hama K., Contos J., et al. LPA3-mediated lysophosphatidic acid signalling in embryo implantation and spacing. Nature 2005, 435:104-108.
18. Hama K., Aoki J., Inoue A., et al. Embryo spacing and implantation timing are differentially regulated by LPA3-mediated lysophosphatidic acid signaling in mice. Biol Reprod 2007, 77:954-959.
19. Tokumura A., Yamano S., Aono T., Fukuzawa K. Lysophosphatidic acids produced by lysophospholipase D in mammalian serum and body fluid. Ann N Y Acad Sci 2000, 905:347-350.
20. Tokumura A., Kanaya Y., Miyake M., Yamano S., Irahara M., Fukuzawa K. Increased production of bioactive lysophosphatidic acid by serum lysophospholipase D in human pregnancy. Biol Reprod 2002, 67:1386-1392.
21. Sibai B., Dekker G., Kupferminc M. Pre-eclampsia. Lancet 2005, 365:785-799.
22. Khan K., Wojdyla D., Say L., Gülmezoglu A., Van Look P. WHO analysis of causes of maternal death: a systematic review. Lancet 2006, 367:1066-1074.
23. Cockell A., Learmont J., Smárason A., Redman C., Sargent I., Poston L. Human placental syncytiotrophoblast microvillous membranes impair maternal vascular endothelial function. Br J Obstet Gynaecol 1997, 104:235-240.
24. Page N., Woods R., Gardiner S., et al. Excessive placental secretion of neurokinin B during the third trimester causes pre-eclampsia. Nature 2000, 405:797-800.
25. Maynard S., Min J., Merchan J., et al. Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia. J Clin Invest 2003, 111:649-658.
26. Levine R., Maynard S., Qian C., et al. Circulating angiogenic factors and the risk of preeclampsia. N Engl J Med 2004, 350:672-683.
27. Levine R., Lam C., Qian C., et al. Soluble endoglin and other circulating antiangiogenic factors in preeclampsia. N Engl J Med 2006, 355:992-1005.
28. Nakamura K., Igarashi K., Ide K., et al. Validation of an autotaxin enzyme immunoassay in human serum samples and its application to hypoalbuminemia differentiation. Clin Chim Acta 2008, 388:51-58.
29. Masuda A., Nakamura K., Izutsu K., et al. Serum autotaxin measurement in haematological malignancies: a promising marker for follicular lymphoma. Br J Haematol 2008, 143:60-70.
30. Steel R.G.D. A rank sum test for comparing all pairs of treatments. Technometrics 1960, 2:197-207.
31. Dwass M. Some k-sample rank-order tests. Contributions to Probability and Statistics 1960, 198-202. Stanford University Press, Stanford California. I. Olkin, S.G. Ghurye, W. Hoeffding, W.G. Madow, H.B. Mann (Eds.).
32. Kendall R., Wang G., Thomas K. Identification of a natural soluble form of the vascular endothelial growth factor receptor, FLT-1, and its heterodimerization with KDR. Biochem Biophys Res Commun 1996, 226:324-328.
33. Shibuya M. Structure and function of VEGF/VEGF-receptor system involved in angiogenesis. Cell Struct Funct 2001, 26:25-35.
34. Zhou Q., Qiao F., Zhao C., et al. Hypoxic trophoblast-derived sFlt-1 may contribute to endothelial dysfunction: an implication for the mechanism of trophoblast-endothelial dysfunction in preeclampsia. Cell Biol Int 2011, 35:61-66.
35. Watanabe N., Ikeda H., Nakamura K., et al. Both plasma lysophosphatidic acid and serum autotaxin concentrations are increased in chronic hepatitis C. J Clin Gastroenterol 2007, 41:616-623.
36. Iwasawa Y., Fujii T., Nagamatsu T., et al. Expression of autotaxin, an ectoenzyme that produces lysophosphatidic acid, in human placenta. Am J Reprod Immunol 2009, 62:90-95.
37. Koike S., Keino-Masu K., Ohto T., Sugiyama F., Takahashi S., Masu M. Autotaxin/lysophospholipase D-mediated lysophosphatidic acid signaling is required to form distinctive large lysosomes in the visceral endoderm cells of the mouse yolk sac. J Biol Chem 2009, 284:33561-33570.
38. Pijnenborg R., Vercruysse L., Hanssens M. Fetal-maternal conflict, trophoblast invasion, preeclampsia, and the red queen. Hypertens Pregnancy 2008, 27:183-196.
39. Nakagawa H., Ikeda H., Nakamura K., et al. Autotaxin as a novel serum marker of liver fibrosis. Clin Chim Acta 2011, 412:1201-1206.
40. Tokumura A., Kume T., Taira S., et al. Altered activity of lysophospholipase D, which produces bioactive lysophosphatidic acid and choline, in serum from women with pathological pregnancy. Mol Hum Reprod 2009, 15:301-310.