Regulation of chemerin chemoattractant and antibacterial activity by human cysteine cathepsins

Journal of Immunology

Volumn 187, Issue 3, 2011, Pages 1403-1410

  Kulig, Paulina ^a   Kantyka, Tomasz ^a   Zabel, Brian A ^b   Banaś, Magdalena ^a   Chyra, Agnieszka ^a   Stefańska, Anna ^a   Tu, Hua ^c   Allen, Samantha J ^d   Handel, Tracy M ^d   Kozik, Andrzej ^a   Potempa, Jan ^a,e   Butcher, Eugene C ^b,f   Cichy, Joanna ^a  

^a JAGIELLONIAN UNIVERSITY   (Poland)

^b VA PALO ALTO HEALTH CARE SYSTEM   (United States)

^c LakePharma Inc   (United States)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^e UNIVERSITY OF LOUISVILLE SCHOOL OF MEDICINE   (United States)

^f STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN K; CATHEPSIN L; CHEMERIN; CHEMOTACTIC FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BACTERIAL IMMUNITY; CELL MIGRATION; CONTROLLED STUDY; ENTEROBACTERIACEAE; ENZYME INHIBITION; ENZYME SUBSTRATE; EX VIVO STUDY; HOST RESISTANCE; HUMAN; HUMAN CELL; NONHUMAN; PLASMACYTOID DENDRITIC CELL; PRIORITY JOURNAL;

ANIMALS; ANTI-BACTERIAL AGENTS; CATHEPSIN B; CATHEPSIN K; CATHEPSIN L; CELL MOVEMENT; CHEMOKINES; CHEMOTACTIC FACTORS; CHO CELLS; CRICETINAE; CRICETULUS; CYSTEINE PROTEASES; DENDRITIC CELLS; HUMANS; RECEPTORS, CHEMOKINE; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY;

EID: 80051642066     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1002352     Document Type: Article

References (32)

1. Wittamer, V., J. D. Franssen, M. Vulcano, J. F. Mirjolet, E. Le Poul, I. Migeotte, S. Brézillon, R. Tyldesley, C. Blanpain, M. Detheux, et al. 2003. Specific recruitment of antigen-presenting cells by chemerin, a novel processed ligand from human inflammatory fluids. J. Exp. Med. 198: 977-985. (Pubitemid 37248614)
2. Zabel, B. A., A. M. Silverio, and E. C. Butcher. 2005. Chemokine-like receptor 1 expression and chemerin-directed chemotaxis distinguish plasmacytoid from myeloid dendritic cells in human blood. J. Immunol. 174: 244-251. (Pubitemid 40007410)
3. Barnea, G., W. Strapps, G. Herrada, Y. Berman, J. Ong, B. Kloss, R. Axel, and K. J. Lee. 2008. The genetic design of signaling cascades to record receptor activation. Proc. Natl. Acad. Sci. USA 105: 64-69.
4. Zabel, B. A., S. Nakae, L. Zúñiga, J. Y. Kim, T. Ohyama, C. Alt, J. Pan, H. Suto, D. Soler, S. J. Allen, et al. 2008. Mast cell-expressed orphan receptor CCRL2 binds chemerin and is required for optimal induction of IgE-mediated passive cutaneous anaphylaxis. J. Exp. Med. 205: 2207-2220.
5. Zabel, B. A., L. Zuniga, T. Ohyama, S. J. Allen, J. Cichy, T. M. Handel, and E. C. Butcher. 2006. Chemoattractants, extracellular proteases, and the integrated host defense response. Exp. Hematol. 34: 1021-1032. (Pubitemid 44080389)
6. Wittamer, V., B. Bondue, A. Guillabert, G. Vassart, M. Parmentier, and D. Communi. 2005. Neutrophil-mediated maturation of chemerin: a link between innate and adaptive immunity. J. Immunol. 175: 487-493. (Pubitemid 40884353)
7. Zabel, B. A., S. J. Allen, P. Kulig, J. A. Allen, J. Cichy, T. M. Handel, and E. C. Butcher. 2005. Chemerin activation by serine proteases of the coagulation, fibrinolytic, and inflammatory cascades. J. Biol. Chem. 280: 34661-34666. (Pubitemid 41504597)
8. Du, X. Y., B. A. Zabel, T. Myles, S. J. Allen, T. M. Handel, P. P. Lee, E. C. Butcher, and L. L. Leung. 2009. Regulation of chemerin bioactivity by plasma carboxypeptidase N, carboxypeptidase B (activated thrombin-activable fibrinolysis inhibitor), and platelets. J. Biol. Chem. 284: 751-758.
9. Albanesi, C., C. Scarponi, S. Pallotta, R. Daniele, D. Bosisio, S. Madonna, P. Fortugno, S. Gonzalvo-Feo, J. D. Franssen, M. Parmentier, et al. 2009. Chemerin expression marks early psoriatic skin lesions and correlates with plasmacytoid dendritic cell recruitment. J. Exp. Med. 206: 249-258.
10. Parolini, S., A. Santoro, E. Marcenaro, W. Luini, L. Massardi, F. Facchetti, D. Communi, M. Parmentier, A. Majorana, M. Sironi, et al. 2007. The role of chemerin in the colocalization of NK and dendritic cell subsets into inflamed tissues. Blood 109: 3625-3632. (Pubitemid 46641708)
11. Skrzeczyńska-Moncznik, J., A. Stefańska, B. A. Zabel, M. Kapińska- Mrowiecka, E. C. Butcher, and J. Cichy. 2009. Chemerin and the recruitment of NK cells to diseased skin. Acta Biochim. Pol. 56: 355-360.
12. Skrzeczyńska-Moncznik, J., K. Wawro, A. Stefańska, E. Oleszycka, P. Kulig, B. A. Zabel, M. Sułkowski, M. Kapińska- Mrowiecka, M. Czubak-Macugowska, E. C. Butcher, and J. Cichy. 2009. Potential role of chemerin in recruitment of plasmacytoid dendritic cells to diseased skin. Biochem. Biophys. Res. Commun. 380: 323-327.
13. Kulig, P., B. A. Zabel, G. Dubin, S. J. Allen, T. Ohyama, J. Potempa, T. M. Handel, E. C. Butcher, and J. Cichy. 2007. Staphylococcus aureus-derived staphopain B, a potent cysteine protease activator of plasma chemerin. J. Immunol. 178: 3713-3720. (Pubitemid 46417639)
14. Brix, K., A. Dunkhorst, K. Mayer, and S. Jordans. 2008. Cysteine cathepsins: cellular roadmap to different functions. Biochimie 90: 194-207. (Pubitemid 351172569)
15. Mohamed, M. M., and B. F. Sloane. 2006. Cysteine cathepsins: multifunctional enzymes in cancer. Nat. Rev. Cancer 6: 764-775. (Pubitemid 44450465)
16. Funicello, M., M. Novelli, M. Ragni, T. Vottari, C. Cocuzza, J. Soriano-Lopez, C. Chiellini, F. Boschi, P. Marzola, P. Masiello, et al. 2007. Cathepsin K null mice show reduced adiposity during the rapid accumulation of fat stores. PLoS ONE 2: e683.
17. Reddy, V. Y., Q. Y. Zhang, and S. J. Weiss. 1995. Pericellular mobilization of the tissue-destructive cysteine proteinases, cathepsins B, L, and S, by human monocyte-derived macrophages. Proc. Natl. Acad. Sci. USA 92: 3849-3853.
18. Yang, M., Y. Zhang, J. Pan, J. Sun, J. Liu, P. Libby, G. K. Sukhova, A. Doria, N. Katunuma, O. D. Peroni, et al. 2007. Cathepsin L activity controls adipogenesis and glucose tolerance. Nat. Cell Biol. 9: 970-977. (Pubitemid 47190452)
19. Sørensen, O. E., P. Follin, A. H. Johnsen, J. Calafat, G. S. Tjabringa, P. S. Hiemstra, and N. Borregaard. 2001. Human cathelicidin, hCAP-18, is processed to the antimicrobial peptide LL-37 by extracellular cleavage with proteinase 3. Blood 97: 3951-3959.
20. Zaiou, M., V. Nizet, and R. L. Gallo. 2003. Antimicrobial and protease inhibitory functions of the human cathelicidin (hCAP18/LL-37) prosequence. J. Invest. Dermatol. 120: 810-816. (Pubitemid 36529083)
21. Zabel, B. A., T. Ohyama, L. Zuniga, J. Y. Kim, B. Johnston, S. J. Allen, D. G. Guido, T. M. Handel, and E. C. Butcher. 2006. Chemokine-like receptor 1 expression by macrophages in vivo: regulation by TGF-beta and TLR ligands. Exp. Hematol. 34: 1106-1114. (Pubitemid 44080376)
22. Radetsky, M., R. C. Wheeler, M. H. Roe, and J. K. Todd. 1986. Microtiter broth dilution method for yeast susceptibility testing with validation by clinical outcome. J. Clin. Microbiol. 24: 600-606. (Pubitemid 16014558)
23. Cash, J. L., R. Hart, A. Russ, J. P. Dixon, W. H. Colledge, J. Doran, A. G. Hendrick, M. B. Carlton, and D. R. Greaves. 2008. Synthetic chemer-inderived peptides suppress inflammation through ChemR23. J. Exp. Med. 205: 767-775. (Pubitemid 351549876)
24. Serveau-Avesque, C., M. F. Martino, V. Hervé-Grépinet, E. Hazouard, F. Gauthier, E. Diot, and G. Lalmanach. 2006. Active cathepsins B, H, K, L and S in human inflammatory bronchoalveolar lavage fluids. Biol. Cell 98: 15-22. (Pubitemid 43056290)
25. Bühling, F., C. Röcken, F. Brasch, R. Hartig, Y. Yasuda, P. Saftig, D. Brömme, and T. Welte. 2004. Pivotal role of cathepsin K in lung fibrosis. Am. J. Pathol. 164: 2203-2216. (Pubitemid 38669366)
26. Bylaite, M., H. Moussali, I. Marciukaitiene, T. Ruzicka, and M. Walz. 2006. Expression of cathepsin L and its inhibitor hurpin in inflammatory and neoplastic skin diseases. Exp. Dermatol. 15: 110-118.
27. Hou, W. S., Z. Li, R. E. Gordon, K. Chan, M. J. Klein, R. Levy, M. Keysser, G. Keyszer, and D. Brömme. 2001. Cathepsin k is a critical protease in synovial fibroblast-mediated collagen degradation. Am. J. Pathol. 159: 2167-2177. (Pubitemid 33104271)
28. Skrzeczyńska-Moncznik, J., K. Wawro, A. Stefańska, E. Oleszycka, P. Kulig, B. A. Zabel, M. Sulkowski, M. Kapińska-Mrowiecka, M. Czubak-Macugowska, E. C. Butcher, and J. Cichy. 2009. Potential role of chemerin in recruitment of plasmacytoid dendritic cells to diseased skin. Biochem. Biophys. Res. Commun. 380: 323-327.
29. de Heer, H. J., H. Hammad, T. Soullié, D. Hijdra, N. Vos, M. A. Willart, H. C. Hoogsteden, and B. N. Lambrecht. 2004. Essential role of lung plasmacytoid dendritic cells in preventing asthmatic reactions to harmless inhaled antigen. J. Exp. Med. 200: 89-98. (Pubitemid 38924731)
30. Allen, S. J., B. A. Zabel, J. Kirkpatrick, E. C. Butcher, D. Nietlispach, and T. M. Handel. 2007. NMR assignment of human chemerin, a novel chemoattractant. Biomol. NMR Assign. 1: 171-173.
31. Zasloff, M. 2002. Antimicrobial peptides of multicellular organisms. Nature 415: 389-395. (Pubitemid 34100944)
32. Wiedemann, I., E. Breukink, C. van Kraaij, O. P. Kuipers, G. Bierbaum, B. de Kruijff, and H. G. Sahl. 2001. Specific binding of nisin to the peptidoglycan precursor lipid II combines pore formation and inhibition of cell wall biosynthesis for potent antibiotic activity. J. Biol. Chem. 276: 1772-1779. (Pubitemid 32109649)