Subunit interface residues F129 and H294 of human RAD51 are essential for recombinase function

PLoS ONE

Volumn 6, Issue 8, 2011, Pages

  Amunugama, Ravindra ^a   Fishel, Richard ^a,b  

^a THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; NUCLEOPROTEIN; NUCLEOPROTEIN FILAMENT; RAD51 PROTEIN; SODIUM CHLORIDE; UNCLASSIFIED DRUG; DNA; HISTIDINE; PHENYLALANINE; RAD51 PROTEIN, HUMAN; SINGLE STRANDED DNA;

ALLOSTERISM; AMINO ACID SUBSTITUTION; ARTICLE; CATALYSIS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME STRUCTURE; ENZYME SUBUNIT; HUMAN; L2 SINGE STRANDED DNA BINDING REGION; NONHUMAN; PROTEIN DNA BINDING; PROTEIN STRUCTURE; STRUCTURAL HOMOLOGY; WALKER A BOX; AMINO ACID SEQUENCE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; DOUBLE STRANDED DNA BREAK; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; GENETICS; METABOLISM; MOLECULAR GENETICS; MUTATION; PROTEIN SUBUNIT; RECOMBINATION REPAIR; SEQUENCE HOMOLOGY; SURFACE PLASMON RESONANCE;

ARCHAEA;

ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BINDING SITES; CATALYTIC DOMAIN; DNA; DNA BREAKS, DOUBLE-STRANDED; DNA, SINGLE-STRANDED; HISTIDINE; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PHENYLALANINE; PROTEIN SUBUNITS; RAD51 RECOMBINASE; RECOMBINATIONAL DNA REPAIR; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY; SURFACE PLASMON RESONANCE;

EID: 80051638420     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0023071     Document Type: Article

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