Resistance to liver fluke infection in the natural sheep host is correlated with a type-1 cytokine response

Parasite Immunology

Volumn 33, Issue 9, 2011, Pages 495-505

  Pleasance, J ^a   Wiedosari, E ^b   Raadsma, H W ^c   Meeusen, E ^a   Piedrafita, David ^a  

^a MONASH UNIVERSITY   (Australia)

^b Research Institute for Veterinary Science Bogor   (Indonesia)

^c UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Cytokines; Eosinophils; Helminth; Parasites; Spleen and lymph nodes; Th1 Th2 Cells

Indexed keywords

GAMMA INTERFERON; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; INTERLEUKIN 4; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; CYTOKINE RESPONSE; FASCIOLA GIGANTICA; FASCIOLA HEPATICA; FASCIOLIASIS; HOST PARASITE INTERACTION; HOST RESISTANCE; IMMUNE RESPONSE; IMMUNOPHENOTYPING; INFECTION RESISTANCE; NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITE MIGRATION; PRIORITY JOURNAL; SHEEP;

ANIMALS; ANTIBODIES, HELMINTH; CD4-POSITIVE T-LYMPHOCYTES; CYTOKINES; DISEASE RESISTANCE; EOSINOPHILS; FASCIOLA; FASCIOLIASIS; FEMALE; IMMUNITY, CELLULAR; INDONESIA; MALE; RNA, MESSENGER; SHEEP; SHEEP DISEASES; SPECIES SPECIFICITY;

FASCIOLA; FASCIOLA GIGANTICA; FASCIOLA HEPATICA; OVIS ARIES; VERMES;

EID: 80051634717     PISSN: 01419838     EISSN: 13653024     Source Type: Journal    
DOI: 10.1111/j.1365-3024.2011.01305.x     Document Type: Article

References (42)

1. Jankovic D, Sher A & Yap G. Th1/Th2 effector choice in parasitic infection: decision making by committee. Curr Opin Immunol 2001; 13: 403-409.
2. Maizels RM, Balic A, Gomez-Escobar N, Nair M, Taylor MD & Allen JE. Helminth parasites - masters of regulation. Immunol Rev 2004; 201: 89-116.
3. Moreau E & Chauvin A. Immunity against helminths: interactions with the host and the intercurrent infections. J Biomed Biotechnol 2010; 2010: 428-593.
4. Hewitson JP, Grainger JR & Maizels RM. Helminth immunoregulation: the role of parasite secreted proteins in modulating host immunity. Mol Biochem Parasitol 2009; 167: 1-11.
5. Dessein A, Kouriba B, Eboumbou C, et al. Interleukin-13 in the skin and interferon-gamma in the liver are key players in immune protection in human schistosomiasis. Immunol Rev 2004; 201: 180-190.
6. McManus DP & Loukas A. Current status of vaccines for schistosomiasis. Clin Microbiol Rev 2008; 21: 225-242.
7. Spithill TW, Smooker PM & Copeman DB. Fasciola gigantica, Epidemiology, Control, Immunology and Molecular Biology. In Dalton JP (ed.): Fasciolosis, Oxon, UK, CABI Publishing, 1999: 465-525.
8. Mas-Coma S. Epidemiology of fascioliasis in human endemic areas. J Helminthol 2005; 79: 207-216.
9. Robinson MW & Dalton JP. Zoonotic helminth infections with particular emphasis on fasciolosis and other trematodiases. Philos Trans R Soc Lond B Biol Sci 2009; 364: 2763-2776.
10. Mas-Coma S, Valero MA & Bargues MD. Climate change effects on trematodiases, with emphasis on zoonotic fascioliasis and schistosomiasis. Vet Parasitol 2009; 163: 264-280.
11. Mulcahy G, Joyce P & Dalton JP. Immunology of Fasciola hepatica infection. In Dalton JP (ed.): Fasciolosis, Oxon, UK, CABI Publishing, 1999: 341-376.
12. Waweru JG, Kanyari PW, Mwangi DM, Ngatia TA & Nansen P. Comparative parasitological and haematological changes in two breeds of sheep infected with Fasciola gigantica. Trop Anim Health Prod 1999; 31: 363-372.
13. Zhang W, Moreau E, Huang W & Chauvin A. Comparison of humoral response in sheep to Fasciola hepatica and Fasciola gigantica experimental infection. Parasite 2004; 11: 153-159.
14. Hansen DS, Clery DG, Estuningsih SE, Widjajanti S, Partoutomo S & Spithill TW. Immune responses in Indonesian thin tail and Merino sheep during a primary infection with Fasciola gigantica: lack of a specific IgG2 antibody response is associated with increased resistance to infection in Indonesian sheep. Int J Parasitol 1999; 29: 1027-1035.
15. Pleasance J, Raadsma HW, Estuningsih SE, Widjajanti S, Meeusen E & Piedrafita D. Innate and adaptive resistance of Indonesian Thin Tail sheep to liver fluke: a comparative analysis of Fasciola gigantica and F. hepatica infection. Vet Parasitol 2010; 178: 264-272.
16. Estuningsih SE, Smooker PM, Wiedosari E, et al. Evaluation of antigens of Fasciola gigantica as vaccines against tropical fasciolosis in cattle. Int J Parasitol 1997; 27: 1419-1428.
17. Raadsma HW, Kingsford NM, Suharyanta, Spithill TW & Piedrafita D. Host responses during experimental infection with Fasciola gigantica or Fasciola hepatica in Merino sheep I. Comparative immunological and plasma biochemical changes during early infection. Vet Parasitol 2007; 143: 275-286.
18. Roberts JA, Widjayanti S, Estuningsih E & Hetzel DJ. Evidence for a major gene determining the resistance of Indonesian Thin Tail sheep against Fasciola gigantica. Vet Parasitol 1997; 68: 309-314.
19. Hein WR, Barber T, Cole SA, Morrison L & Pernthaner A. Long-term collection and characterization of afferent lymph from the ovine small intestine. J Immunol Methods 2004; 293: 153-168.
20. Konnai S, Usui T, Ohashi K & Onuma M. The rapid quantitative analysis of bovine cytokine genes by real-time RT-PCR. Vet Microbiol 2003; 94: 283-294.
21. Pfaffl MW. Quantification strategies in real-time PCR. In Bustin SA (ed.): A-Z of quantitative PCR, La Jolla, CA, USA, International University Line, 2004: 87-120.
22. Pfaffl MW, Horgan GW & Dempfle L. Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acids Res 2002; 30: e36.
23. Meeusen EN & Balic A. Do eosinophils have a role in the killing of helminth parasites? Parasitol Today 2000; 16: 95-101.
24. Mocellin S, Provenzano M, Rossi CR, Pilati P, Nitti D & Lise M. Use of quantitative real-time PCR to determine immune cell density and cytokine gene profile in the tumor microenvironment. J Immunol Methods 2003; 280: 1-11.
25. Meeusen E & Brandon M. The use of antibody-secreting cell probes to reveal tissue-restricted immune responses during infection. Eur J Immunol 1994; 24: 469-474.
26. Jungersen G, Eriksen L, Nansen P, Lind P, Rasmussen T & Meeusen EN. Regional immune responses with stage-specific antigen recognition profiles develop in lymph nodes of pigs following Ascaris suum larval migration. Parasite Immunol 2001; 23: 185-194.
27. Behm CA & Sangester NC. Pathology, pathophysiology and clinical aspects. In Dalton JP (ed.): Fasciolosis, Oxon, UK, CABI Publishing, 1999: 185-224.
28. Estes DM & Brown WC. Type 1 and type 2 responses in regulation of Ig isotype expression in cattle. Vet Immunol Immunopathol 2002; 90: 1-10.
29. Piedrafita D, Raadsma H, Prowse R & Spithill TW. Immunology of the host parasite relationship in Fasciolosis (Fasciola hepatica and Fasciola gigantica). Can J Zool 2004; 82: 233-250.
30. Hoyle DV & Taylor DW. The immune response of regional lymph nodes during the early stages of Fasciola hepatica infection in cattle. Parasite Immunol 2003; 25: 221-229.
31. O'Neill SM, Brady MT, Callanan JJ, et al. Fasciola hepatica infection downregulates Th1 responses in mice. Parasite Immunol 2000; 22: 147-155.
32. Tliba O, Sibille P, Boulard C & Chauvin A. Early hepatic cytokine mRNA expression in experimental rat fasciolosis. Vet Parasitol 2002; 103: 237-249.
33. Meeusen E, Lee C, Rickard M & Brandon MR. Cellular responses during liver fluke infection in sheep and its evasion by the parasite. Parasite Immunol 1995; 17: 35-45.
34. Perez J, Ortega J, Bravo A, et al. Phenotype of hepatic infiltrates and hepatic lymph nodes of lambs primarily and challenge infected with Fasciola hepatica, with and without triclabendazole treatment. Vet Res 2005; 36: 1-12.
35. Roberts JA, Estuningsih E, Wiedosari E & Spithill TW. Acquisition of resistance against Fasciola gigantica by Indonesian thin tail sheep. Vet Parasitol 1997; 73: 215-224.
36. Hacariz O, Sayers G, Flynn RJ, Lejeune A & Mulcahy G. IL-10 and TGF-beta1 are associated with variations in fluke burdens following experimental fasciolosis in sheep. Parasite Immunol 2009; 31: 613-622.
37. Wiedosari E, Hayakawa H & Copeman DB. Host differences in response to trickle infection with Fasciola gigantica in buffalo, Ongole and Bali calves. Trop Anim Health Prod 2006; 38: 43-53.
38. Mulcahy G, O'Connor F, McGonigle S, et al. Correlation of specific antibody titre and avidity with protection in cattle immunized against Fasciola hepatica. Vaccine 1998; 16: 932-939.
39. Golden O, Flynn RJ, Read C, et al. Protection of cattle against a natural infection of Fasciola hepatica by vaccination with recombinant cathepsin L1 (rFhCL1). Vaccine 2010; 28: 5551-5557.
40. Roberts JA, Estuningsih E, Widjayanti S, Wiedosari E, Partoutomo S & Spithill TW. Resistance of Indonesian thin tail sheep against Fasciola gigantica and F. hepatica. Vet Parasitol 1997; 68: 69-78.
41. Zhang WY, Moreau E, Hope JC, Howard CJ, Huang WY & Chauvin A. Fasciola hepatica and Fasciola gigantica: comparison of cellular response to experimental infection in sheep. Exp Parasitol 2005; 111: 154-159.
42. Piedrafita D, Estuningsih E, Pleasance J, et al. Peritoneal lavage cells of Indonesian thin tail sheep mediate antibody-dependent superoxide radical cytotoxicity in vitro against newly excysted juvenile Fasciola gigantica but not juvenile Fasciola hepatica. Infect Immun 2007; 75: 1954-1963.