Gene network inference and biochemical assessment delineates GPCR pathways and CREB targets in small intestinal neuroendocrine neoplasia

PLoS ONE

Volumn 6, Issue 8, 2011, Pages

  Drozdov, Ignat ^a   Svejda, Bernhard ^b   Gustafsson, Bjorn I ^c   Mane, Shrikant ^b   Pfragner, Roswitha ^d   Kidd, Mark ^b   Modlin, Irvin M ^b  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c TRONDHEIM UNIVERSITY HOSPITAL   (Norway)

^d MEDICAL UNIVERSITY OF GRAZ   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR BETA3; ADENYLATE CYCLASE; ADENYLATE CYCLASE 2; BICAUDAL D HOMOLOG 1; BRAIN EXPRESSED X LINKED PROTEIN 1; CARBOXYPEPTIDASE H; CHROMOGRANIN B; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE REGULATORY SUBUNIT IALPHA; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLIC AMP SYNTHETASE; DOPAMINE 2 RECEPTOR STIMULATING AGENT; G PROTEIN COUPLED RECEPTOR; ISOPRENALINE; SECRETOGRANIN II; SECRETOGRANIN III; SYNTHETASE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; CYCLIC AMP; MESSENGER RNA; TUMOR PROTEIN;

ARTICLE; CELL CYCLE; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; ENZYME ACTIVITY; GENE EXPRESSION; GENE REGULATORY NETWORK; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; NERVOUS SYSTEM DEVELOPMENT; NEUROENDOCRINE TUMOR; SIGNAL TRANSDUCTION; SMALL INTESTINE TUMOR; TUMOR GROWTH; UPREGULATION; BIOLOGICAL MODEL; BIOLOGY; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENETIC DATABASE; GENETIC TRANSCRIPTION; GENETICS; INTESTINE TUMOR; METABOLISM; PATHOLOGY; PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; REPRODUCIBILITY; SMALL INTESTINE;

COMPUTATIONAL BIOLOGY; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DATABASES, GENETIC; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE REGULATORY NETWORKS; HUMANS; INTESTINAL NEOPLASMS; INTESTINE, SMALL; MODELS, GENETIC; NEOPLASM PROTEINS; NEUROENDOCRINE TUMORS; PHOSPHORYLATION; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, G-PROTEIN-COUPLED; REPRODUCIBILITY OF RESULTS; RESPONSE ELEMENTS; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC;

EID: 80051619308     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0022457     Document Type: Article

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