Isolation of genes involved in biofilm formation of a klebsiella pneumoniae strain causing pyogenic liver abscess

PLoS ONE

Volumn 6, Issue 8, 2011, Pages

  Wu, Meng Chuan ^a   Lin, Tzu Lung ^a   Hsieh, Pei Fang ^a   Yang, Hui Ching ^a   Wang, Jin Town ^a,b  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROLASE; POLYSACCHARIDE; TREHALOSE 6 PHOSPHATE HYDROLASE; UNCLASSIFIED DRUG; ALPHA, ALPHA PHOSPHOTREHALASE; ALPHA, ALPHA-PHOSPHOTREHALASE; BACTERIAL PROTEIN; DISACCHARIDASE; MEMBRANE PROTEIN; TREHALOSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL GENE; BACTERIUM CULTURE; BIOFILM; CAPSULAR POLYSACCHARIDE GENE; CARBOHYDRATE METABOLISM; CONTROLLED STUDY; GENE EXPRESSION; GENE IDENTIFICATION; GENE ISOLATION; IN VITRO STUDY; IN VIVO STUDY; KLEBSIELLA PNEUMONIAE; MICROTITER PLATE ASSAY; MOUSE; MUCUS SECRETION; NONHUMAN; NUCLEOTIDE SEQUENCE; PYOGENIC LIVER ABSCESS; SUGE GENE; TRANSPOSON; TREC GENE; UPREGULATION; VISCOSITY; ANIMAL; BACTERIAL MEMBRANE; BAGG ALBINO MOUSE; FEMALE; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; ISOLATION AND PURIFICATION; KLEBSIELLA INFECTION; MALE; METABOLISM; MICROBIOLOGY; MUTATION; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

BACTERIA (MICROORGANISMS); KLEBSIELLA PNEUMONIAE; MUS;

ANIMALS; BACTERIAL CAPSULES; BACTERIAL PROTEINS; BIOFILMS; DISACCHARIDASES; FEMALE; GENE EXPRESSION REGULATION, BACTERIAL; HUMANS; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; LIVER ABSCESS, PYOGENIC; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED BALB C; MUTATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TREHALOSE;

EID: 80051616335     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0023500     Document Type: Article

References (43)

1. Podschun R, Ullmann U, (1998) Klebsiella spp. as nosocomial pathogens: epidemiology, taxonomy, typing methods, and pathogenicity factors. Clin Microbiol Rev 11: 589-603.
2. Ramphal R, Ambrose PG, (2006) Extended-spectrum beta-lactamases and clinical outcomes: current data. Clin Infect Dis 42 (Suppl 4): S164-172.
3. Chang SC, Fang CT, Hsueh PR, Chen YC, Luh KT, (2000) Klebsiella pneumoniae isolates causing liver abscess in Taiwan. Diagn Microbiol Infect Dis 37: 279-284.
4. Chuang YP, Fang CT, Lai SY, Chang SC, Wang JT, (2006) Genetic determinants of capsular serotype K1 of Klebsiella pneumoniae causing primary pyogenic liver abscess. J Infect Dis 193: 645-654.
5. Fung CP, Chang FY, Lee SC, Hu BS, Kuo BI, et al. (2002) A global emerging disease of Klebsiella pneumoniae liver abscess: is serotype K1 an important factor for complicated endophthalmitis? Gut 50: 420-424.
6. Ko WC, Paterson DL, Sagnimeni AJ, Hansen DS, Von Gottberg A, et al. (2002) Community-acquired Klebsiella pneumoniae bacteremia: global differences in clinical patterns. Emerg Infect Dis 8: 160-166.
7. Chen W, Chen CH, Chiu KL, Lai HC, Liao KF, et al. (2008) Clinical outcome and prognostic factors of patients with pyogenic liver abscess requiring intensive care. Crit Care Med 36: 1184-1188.
8. Chou FF, Sheen-Chen SM, Chen YS, Chen MC, (1997) Single and multiple pyogenic liver abscesses: clinical course, etiology, and results of treatment. World J Surg 21: 384-388; discussion 388-389.
9. Chung DR, Lee SS, Lee HR, Kim HB, Choi HJ, et al. (2007) Emerging invasive liver abscess caused by K1 serotype Klebsiella pneumoniae in Korea. J Infect 54: 578-583.
10. Yeoh KG, Yap I, Wong ST, Wee A, Guan R, et al. (1997) Tropical liver abscess. Postgrad Med J 73: 89-92.
11. Tsai FC, Huang YT, Chang LY, Wang JT, (2008) Pyogenic liver abscess as endemic disease, Taiwan. Emerg Infect Dis 14: 1592-1600.
12. Costerton JW, Stewart PS, Greenberg EP, (1999) Bacterial biofilms: a common cause of persistent infections. Science 284: 1318-1322.
13. Mah TF, O'Toole GA, (2001) Mechanisms of biofilm resistance to antimicrobial agents. Trends Microbiol 9: 34-39.
14. Elkins JG, Hassett DJ, Stewart PS, Schweizer HP, McDermott TR, (1999) Protective role of catalase in Pseudomonas aeruginosa biofilm resistance to hydrogen peroxide. Appl Environ Microbiol 65: 4594-4600.
15. Donlan RM, Costerton JW, (2002) Biofilms: survival mechanisms of clinically relevant microorganisms. Clin Microbiol Rev 15: 167-193.
16. Zhang L, Mah TF, (2008) Involvement of a novel efflux system in biofilm-specific resistance to antibiotics. J Bacteriol 190: 4447-4452.
17. Anderl JN, Franklin MJ, Stewart PS, (2000) Role of antibiotic penetration limitation in Klebsiella pneumoniae biofilm resistance to ampicillin and ciprofloxacin. Antimicrob Agents Chemother 44: 1818-1824.
18. Wellman N, Fortun SM, McLeod BR, (1996) Bacterial biofilms and the bioelectric effect. Antimicrob Agents Chemother 40: 2012-2014.
19. Jagnow J, Clegg S, (2003) Klebsiella pneumoniae MrkD-mediated biofilm formation on extracellular matrix- and collagen-coated surfaces. Microbiology 149: 2397-2405.
20. Balestrino D, Haagensen JA, Rich C, Forestier C, (2005) Characterization of type 2 quorum sensing in Klebsiella pneumoniae and relationship with biofilm formation. J Bacteriol 187: 2870-2880.
21. Boddicker JD, Anderson RA, Jagnow J, Clegg S, (2006) Signature-tagged mutagenesis of Klebsiella pneumoniae to identify genes that influence biofilm formation on extracellular matrix material. Infect Immun 74: 4590-4597.
22. Balestrino D, Ghigo JM, Charbonnel N, Haagensen JA, Forestier C, (2008) The characterization of functions involved in the establishment and maturation of Klebsiella pneumoniae in vitro biofilm reveals dual roles for surface exopolysaccharides. Environ Microbiol 10: 685-701.
23. Ma LC, Fang CT, Lee CZ, Shun CT, Wang JT, (2005) Genomic heterogeneity in Klebsiella pneumoniae strains is associated with primary pyogenic liver abscess and metastatic infection. J Infect Dis 192: 117-128.
24. O'Toole GA, Kolter R, (1998) Flagellar and twitching motility are necessary for Pseudomonas aeruginosa biofilm development. Mol Microbiol 30: 295-304.
25. Lai YC, Peng HL, Chang HY, (2003) RmpA2, an activator of capsule biosynthesis in Klebsiella pneumoniae CG43, regulates K2 cps gene expression at the transcriptional level. J Bacteriol 185: 788-800.
26. Hsieh PF, Lin TL, Lee CZ, Tsai SF, Wang JT, (2008) Serum-induced iron-acquisition systems and TonB contribute to virulence in Klebsiella pneumoniae causing primary pyogenic liver abscess. J Infect Dis 197: 1717-1727.
27. Link AJ, Phillips D, Church GM, (1997) Methods for generating precise deletions and insertions in the genome of wild-type Escherichia coli: application to open reading frame characterization. J Bacteriol 179: 6228-6237.
28. Hsieh PF, Lin HH, Lin TL, Wang JT, (2010) CadC regulates cad and tdc operons in response to gastrointestinal stresses and enhances intestinal colonization of Klebsiella pneumoniae. J Infect Dis 202: 52-64.
29. Livak KJ, Schmittgen TD, (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408.
30. Fang CT, Chuang YP, Shun CT, Chang SC, Wang JT, (2004) A novel virulence gene in Klebsiella pneumoniae strains causing primary liver abscess and septic metastatic complications. J Exp Med 199: 697-705.
31. Klein W, Horlacher R, Boos W, (1995) Molecular analysis of treB encoding the Escherichia coli enzyme II specific for trehalose. J Bacteriol 177: 4043-4052.
32. Rimmele M, Boos W, (1994) Trehalose-6-phosphate hydrolase of Escherichia coli. J Bacteriol 176: 5654-5664.
33. Rosen DA, Pinkner JS, Walker JN, Elam JS, Jones JM, et al. (2008) Molecular variations in Klebsiella pneumoniae and Escherichia coli FimH affect function and pathogenesis in the urinary tract. Infect Immun 76: 3346-3356.
34. Wang X, Preston JF 3rd, Romeo T, (2004) The pgaABCD locus of Escherichia coli promotes the synthesis of a polysaccharide adhesin required for biofilm formation. J Bacteriol 186: 2724-2734.
35. Di Martino P, Cafferini N, Joly B, Darfeuille-Michaud A, (2003) Klebsiella pneumoniae type 3 pili facilitate adherence and biofilm formation on abiotic surfaces. Res Microbiol 154: 9-16.
36. Frees D, Chastanet A, Qazi S, Sorensen K, Hill P, et al. (2004) Clp ATPases are required for stress tolerance, intracellular replication and biofilm formation in Staphylococcus aureus. Mol Microbiol 54: 1445-1462.
37. Hammer BK, Bassler BL, (2003) Quorum sensing controls biofilm formation in Vibrio cholerae. Mol Microbiol 50: 101-104.
38. Zamze S, Martinez-Pomares L, Jones H, Taylor PR, Stillion RJ, et al. (2002) Recognition of bacterial capsular polysaccharides and lipopolysaccharides by the macrophage mannose receptor. J Biol Chem 277: 41613-41623.
39. Cheng HY, Chen YS, Wu CY, Chang HY, Lai YC, et al. (2010) RmpA regulation of capsular polysaccharide biosynthesis in Klebsiella pneumoniae CG43. J Bacteriol 192: 3144-3158.
40. Sikora CW, Turner RJ, (2005) SMR proteins SugE and EmrE bind ligand with similar affinity and stoichiometry. Biochem Biophys Res Commun 335: 105-111.
41. Sledjeski DD, Gottesman S, (1996) Osmotic shock induction of capsule synthesis in Escherichia coli K-12. J Bacteriol 178: 1204-1206.
42. Swidsinski A, Weber J, Loening-Baucke V, Hale LP, Lochs H, (2005) Spatial organization and composition of the mucosal flora in patients with inflammatory bowel disease. J Clin Microbiol 43: 3380-3389.
43. Macfarlane S, (2008) Microbial biofilm communities in the gastrointestinal tract. J Clin Gastroenterol 42 (Suppl 3 Pt 1): S142-143.