Melatonin and β-glucan alone or in combination inhibit the growth of dunning prostatic adenocarcinoma

Oncology Research

Volumn 19, Issue 6, 2011, Pages 259-263

  Kabasakal, Levent ^a   Şener, Göksel ^a   Balkan, Jale ^b   Doǧru Abbasoǧlu, Semra ^c   Keyer Uysal, Meral ^a   Uysal, Müjdat ^c  

^a MARMARA UNIVERSITY   (Turkey)

^b YEDITEPE UNIVERSITY   (Turkey)

^c ISTANBUL UNIVERSITY   (Turkey)

Author keywords

Antioxidant enzymes; Lipid peroxidation; MatLyLu dunning prostatic adenocarcinoma; Melatonin; Glucan

Indexed keywords

BETA GLUCAN; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; MALONALDEHYDE; RECOMBINANT HORMONE; RECOMBINANT MELATONIN; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; ANTIOXIDANT; MELATONIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CANCER SIZE; CANCER TISSUE; CONTROLLED STUDY; ENZYME ACTIVITY; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROSTATE ADENOCARCINOMA; RAT; TREATMENT DURATION; TREATMENT OUTCOME; ADENOCARCINOMA; ANIMAL; DISEASE MODEL; DRUG EFFECT; LIPID PEROXIDATION; METABOLISM; PATHOLOGY; PROSTATE TUMOR; TUMOR CELL CULTURE; WESTERN BLOTTING;

ADENOCARCINOMA; ANIMALS; ANTIOXIDANTS; BETA-GLUCANS; BLOTTING, WESTERN; DISEASE MODELS, ANIMAL; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; LIPID PEROXIDATION; MALE; MALONDIALDEHYDE; MELATONIN; OXIDATIVE STRESS; PROSTATIC NEOPLASMS; RATS; SUPEROXIDE DISMUTASE; TUMOR CELLS, CULTURED;

EID: 80051608656     PISSN: 09650407     EISSN: None     Source Type: Journal    
DOI: 10.3727/096504011X13021877989748     Document Type: Article

References (41)

1. Oberley, T. D. Oxidative damage and cancer. Am. J. Pathol. 160:403-408; 2002.
2. Klaunig, J. E.; Kamendulis, L. M. The role of oxidative stress in carcinogenesis. Annu. Rev. Pharmacol. Toxicol. 44:239-267; 2004.
3. Valko, M.; Rhodes, C. J.; Moncol, J.; Izakovic, M.; Mazur, M. Free radicals, metals and antioxidants in oxidative stress-induced cancer. Chem. Biol. Interact. 60:1-40; 2006.
4. Sikka, S. C. Role of oxidative stress response elements and antioxidants in prostate cancer pathobiology and chemoprevention-a mechanistic approach. Curr. Med. Chem. 10:2679-2692; 2003.
5. Khandrika, L.; Kumar, B.; Koul, S.; Maroni, P.; Koul, H. K. Oxidative stress in prostate cancer. Cancer Lett. 282:125-136; 2009
6. Ghatak, S.; Ho, S. M. Age-related changes in the activities of antioxidant enzymes and lipid peroxidation status in ventral and dorsolateral prostate lobes of Noble rats. Biochem. Biophys. Res. Commun. 222:362-367; 1996.
7. Malins, D. C.; Johnson, P. M.; Wheeler, T. M.; Barker, E. A.; Polissar, N. L.; Vinson, M. A. Age-related radical-induced DNA damage is linked to prostate cancer. Cancer Res. 61:6025-6028; 2001.
8. Kumar, B.; Koul, S.; Khandrika, L.; Meacham, R. B.; Koul, H. K. Oxidative stress is inherent in prostate cancer cells and is required for aggressive phenotype. Cancer Res. 68:1777-1785; 2008.
9. Siler, U.; Barella, L.; Spitzer, V.; Schnorr, J.; Lein, M.; Goralczyk, R.; Wertz, K. Lycopene and vitamin E interfere with autocrine/paracrine loops in the Dunning prostate cancer model. FASEB J. 18:1019-1021; 2004.
10. Venkateswaran, V.; Fleshner, N. E.; Sugar, L. M.; Klotz, L. H. Antioxidants block prostate cancer in lady transgenic mice. Cancer Res. 64:5891-5896; 2004
11. Tam, N. N. C.; Nyska, A.; Maranpot, R. R.; Kissling, G.; Lomnitski, L.; Suttie, A.; Bakshi, S.; Bergman, M.; Grossman, S.; Ho, S. M. Differential attenuation of oxidative/ nitrosative injuries in early prostatic neoplastic lesions in TRAMP mice by dietary antioxidants. Prostate 66:57-69; 2006.
12. Canene-Adams, K.; Lindshield, B. L.; Wang, S.; Jeffery, E. H.; Clinton, S. K.; Erdman, Jr., J. W. Combinations of tomato and broccoli enhance antitumor activity in Dunning R3327-H prostate adenocarcinomas. Cancer Res. 67: 836-843; 2007.
13. Tan, D. X.; Chen, L. D.; Poeggeler, B.; Manchester, L. C.; Reiter, R. J. Melatonin: A potent, endogenous hydroxyl radical scavenger. Endocr. J. 1:57-60; 1993.
14. Hardeland, R.; Tan, D. X.; Reiter, R. J. Kynuramines, metabolites of melatonin and other indoles: The resurrection of an almost forgetten class of biogenic amines. J. Pineal Res. 47:109-126; 2009.
15. Rodriguez, C.; Mayo, J. C.; Sainz, R. M. Regulation of antioxidant enzymes: A significant role for melatonin. J. Pineal Res. 36:1-9; 2004.
16. Reiter, R. J.; Tan, D. X.; Korkmaz, A.; Erren, T. C.; Piekarski, C.; Tamura, H.; Manchester, L. C. Light at night, chronodisruption, melatonin suppression, and cancer risk: A review. Crit. Rev. Oncog. 13:303-328; 2007.
17. Hill, S. M.; Frasch, T.; Xiang, S.; Yuan, L.; Duplessis, T.; Mao, L. Molecular mechanisms of melatonin anticancer effects. Integr. Cancer Ther. 8:337-346; 2009.
18. Hevia, D.; Mayo, J. C.; Quiros, L.; Gomez-Cordoves, C.; Sainz, R. M. Monitoring intracellular melatonin levels in human prostate normal and cancer cells by HPLC. Anal. Bioanal. Chem. 397:1235-1244; 2010.
19. Philo, R.; Berkowitz, A. S. Inhibition of Dunning tumor growth by melatonin. J. Urol. 139:1099-1102; 1988.
20. Rahman, K. M. W.; Sugie, S.; Watanabe, T.; Tanaka, T.; Mori, H. Chemopreventive effects of melatonin on diethylnitrosamine and phenobarbital-induced hepatocarcino-genesis in male f344 rats. Nutr. Cancer 47:148-155; 2003.
21. Shiu, S. Y. W. Towards rational and evidence-based use of melatonin in prostate cancer prevention and treatment. J. Pineal Res. 43:1-9; 2007.
22. Srinivasan, V.; Spence, D. W.; Pandi-Perumal, S. R.; Trakht, I.; Cardinali, D. P. Therapeutic actions of melatonin in cancer: Possible mechanisms. Integ. Cancer Ther. 7:189-203; 2008.
23. Chen, J.; Seviour, R. Medicinal importance of fungal β- (1-3), (1-6)-glucans. Mycol. Res. 111:635-652; 2007.
24. Chan, G. C. F.; Chan, W. K.; Sze, D. M. Y. The effects of β-glucan on human immune and cancer cells. J. Hematol. Oncol. 2:25-35; 2009.
25. Mantovani, M. S.; Bellini, M. F.; Angeli, J. P. F.; Oliveira, R. J.; Silva, A. F.; Ribeiro, L. R. β-Glucans in promoting health: Prevention against mutation and cancer. Mutat. Res. 658:154-161; 2008.
26. Sener, G.; Ekşioǧlu-Demiralp, E.; Cetiner, M.; Ercan, F.; Yeǧen, B. C. Beta-glucan ameliorates methotrexate-induced oxidative organ injury via its antioxidant and immunomodulatory effects. Eur. J. Pharmacol. 542:170-178; 2006.
27. Yu, C. H.; Kan, S. F.; Shu, C. H.; Lu, T. J.; Sun-Hwang, L.; Wang, P. S. Inhibitory mechanisms of Agaricus blazei Murill on the growth of prostate cancer in vitro and in vivo. J. Nutr. Biochem 20:753-764; 2009.
28. Vieweg, J.; Rosenthal, F. M.; Bannerji, R.; Heston, W. D.;Fair, W. R.; Gansbacher, B.; Gilboa, E. Immunotherapy of prostate cancer in the Dunning rat model: Use of cytokine gene modified tumor vaccines. Cancer Res. 54: 1760-1765; 1994.
29. Lucia, M. S.; Bostwick, D. G.; Bosland, M.; Cockett, A. T. K.; Knapp, D. W.; Leav, I.; Pollard, M.; Rinker- Schaeffer, C.; Shirai, T.; Watkins, B. A. Workgroup 1. Rodent models of prostate cancer. Prostate 36:49-55; 1998.
30. Jung, K.; Krell, H. W.; Ortel, B.; Hasan, T.; Römer, A.; Schnorr, D.; Loening, S. A.; Lein, M. Plasma matrix metalloproteinase 9 as biomarker of prostate cancer progression in Dunning (Copenhagen) rats. Prostate 54:206-211; 2003.
31. Ohkawa, H.; Ohishi, N.; Yagi, K. Assay for lipid peroxidation in animal tissues by thiobarbituric acid reaction. Anal. Biochem. 95:351-358; 1979.
32. Beutler, E.; Duron, O.; Kelly, B. M. Improved method for the determination of blood glutathione. J. Lab. Clin. Med. 61:882-888; 1963.
33. Mylorie, A. A.; Collins, H.; Umbles, C.; Kyle, J. Erythrocyte superoxide dismutase activity and other parameters of copper status in rats ingesting lead acetate. Toxicol. Appl. Pharmacol. 82:512-520; 1986.
34. Lawrence, R. A.; Burk, R. F. Glutathione peroxidase activity in selenium deficient rat liver. Biochem. Biophys. Res. Commun. 71:952-958; 1976.
35. Habig, W. H.; Jacoby, W. B. Assays for differentation of glutathione s-transferases. Methods Enzymol. 77:398-405; 1981.
36. Smith, P. K.; Krohn, R. I.; Hermanson, G. T.; Mallia, A. K.; Gartner, F. H.; Provenzano, M. D.; Fujimoto, E. K.; Goeke, N. M.; Olson, B. J.; Klenk, D. C. Measure ment of protein using bicinchoninic acid. Anal. Biochem. 150:76-85; 1985.
37. Baker, A. M.; Oberley, L. W.; Cohen, M. B. Expression of antioxidant enzymes in human prostatic adenocarcinoma. Prostate 32:229-233; 1997.
38. Bostwick, D. G.; Alexander, E. E.; Singh, R.; Shan, A.; Qian, J.; Santella, R. M.; Oberley, L. W.; Yan, T.; Zhong, W.; Jiang, X.; Oberley, T. D. Antioxidant enzyme expression and reactive oxygen species damage in prostatic intraepithelial neoplasia and cancer. Cancer 89:123-134; 2000.
39. Canada, A.; Roberson, K. M.; Vessella, R. L.; Trump, D. L.; Robertson, C. N.; Fine, R. L. Glutathione and glutathione S-transferase in benign and malignant prostate cell lines and prostate tissues. Biochem. Pharmacol. 51:87-90; 1996.
40. Jung, K.; Seidel, B.; Rudolph, B.; Lein, M.; Cronauer, M. V.; Henke, W.; Hampel, G.; Schnorr, D.; Loening, S. A. Antioxidant enzymes in malignant prostate cell lines and in primary cultured prostatic cells. Free Radic. Biol. Med. 23:127-133; 1997.
41. Schaefer, M.; Hardeland, R. The melatonin metabolite N-acetyl-5- methoxykynuramine is a potent singlet oxygen scavenger. J. Pineal Res. 46:49-52; 2010.