Attenuation of virulence in an apicomplexan hemoparasite results in reduced genome diversity at the population level

BMC Genomics

Volumn 12, Issue , 2011, Pages

  Lau, Audrey O T ^a   Kalyanaraman, Ananth ^b   Echaide, Ignacio ^c   Palmer, Guy H ^a   Bock, Russell ^d   Pedroni, Monica J ^a   Rameshkumar, Meenakshi ^b   Ferreira, Mariano B ^c   Fletcher, Taryn I ^d,e   McElwain, Terry F ^a  

^a WASHINGTON STATE UNIVERSITY   (United States)

^b Washington State University   (United States)

^c INSTITUTO NACIONAL DE TECNOLOGÍA AGROPECUARIA INTA   (Argentina)

^d Tick Fever Research Centre   (Australia)

^e IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID;

APICOMPLEXA; ARTICLE; BABESIA BOVIS; BLOOD PARASITE; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC DIFFERENCE; GENETIC VARIABILITY; GEOGRAPHIC ORIGIN; NONHUMAN; PARASITE VIRULENCE; POPULATION STRUCTURE; PROTEIN ASSEMBLY; PROTEIN MODIFICATION; PYROSEQUENCING; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; ANIMAL; BLOOD; GENETICS; GENOMICS; GEOGRAPHY; PARASITOLOGY; PATHOGENICITY; PHENOTYPE; SPECIES DIFFERENCE;

BABESIA BOVIS;

ANIMALS; BABESIA BOVIS; BLOOD; GENETIC VARIATION; GENOMICS; GEOGRAPHY; PHENOTYPE; SEQUENCE ANALYSIS; SPECIES SPECIFICITY;

EID: 80051600636     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-12-410     Document Type: Article

References (38)

1. Taylor HM, Kyes SA, Newbold CI. Var gene diversity in Plasmodium falciparum is generated by frequent recombination events. Mol Biochem Parasitol 2000, 110(2):391-397. 10.1016/S0166-6851(00)00286-3, 11071291.
2. Rosenberg SM. Mutation for survival. Curr Opin Genet Dev 1997, 7(6):829-834. 10.1016/S0959-437X(97)80047-0, 9468794.
3. Taddei F, Matic I, Godelle B, Radman M. To be a mutator, or how pathogenic and commensal bacteria can evolve rapidly. Trends Microbiol 1997, 5(11):427-428. discussion 428-429, 10.1016/S0966-842X(97)01157-8, 9402695.
4. Taddei F, Radman M, Maynard-Smith J, Toupance B, Gouyon PH, Godelle B. Role of mutator alleles in adaptive evolution. Nature 1997, 387(6634):700-702. 10.1038/42696, 9192893.
5. Ping J, Dankar SK, Forbes NE, Keleta L, Zhou Y, Tyler S, Brown EG. PB2 and HA Mutations are Major Determinants of Host Range and Virulence in Mouse-Adapted Influenza A Virus. J Virol
6. Engel AR, Rumyantsev AA, Maximova OA, Speicher JM, Heiss B, Murphy BR, Pletnev AG. The neurovirulence and neuroinvasiveness of chimeric tick-borne encephalitis/dengue virus can be attenuated by introducing defined mutations into the envelope and NS5 protein genes and the 3' non-coding region of the genome. Virology 405(1):243-252.
7. Darghouth MA. Review on the experience with live attenuated vaccines against tropical theileriosis in Tunisia: considerations for the present and implications for the future. Vaccine 2008, 26(Suppl 6):G4-G10.
8. Druilhe P, Barnwell JW. Pre-erythrocytic stage malaria vaccines: time for a change in path. Curr Opin Microbiol 2007, 10(4):371-378. 10.1016/j.mib.2007.07.009, 17709281.
9. Florin-Christensen M, Schnittger L, Dominguez M, Mesplet M, Rodriguez A, Ferreri L, Asenzo G, Wilkowsky S, Farber M, Echaide I, et al. Search for Babesia bovis vaccine candidates. Parassitologia 2007, 49(Suppl 1):9-12.
10. Allred DR. Antigenic variation in Babesia bovis: how similar is it to that in Plasmodium falciparum?. Ann Trop Med Parasitol 1998, 92(4):461-472. 10.1080/00034989859438, 9683897.
11. Shkap V, de Vos AJ, Zweygarth E, Jongejan F. Attenuated vaccines for tropical theileriosis, babesiosis and heartwater: the continuing necessity. Trends Parasitol 2007, 23(9):420-426. 10.1016/j.pt.2007.07.003, 17656155.
12. Shkap V, Leibovitz B, Krigel Y, Hammerschlag J, Marcovics A, Fish L, Molad T, Savitsky I, Mazuz M. Vaccination of older Bos taurus bulls against bovine babesiosis. Vet Parasitol 2005, 129(3-4):235-242. 10.1016/j.vetpar.2005.01.013, 15845278.
13. Bock RE, de Vos AJ. Immunity following use of Australian tick fever vaccine: a review of the evidence. Aust Vet J 2001, 79(12):832-839. 10.1111/j.1751-0813.2001.tb10931.x, 11837905.
14. Brayton KA, Lau AO, Herndon DR, Hannick L, Kappmeyer LS, Berens SJ, Bidwell SL, Brown WC, Crabtree J, Fadrosh D, et al. Genome sequence of Babesia bovis and comparative analysis of apicomplexan hemoprotozoa. PLoS Pathog 2007, 3(10):1401-1413. 2034396, 17953480.
15. Bock RE, de Vos AJ, Lew A, Kingston TG, Fraser IR. Studies on failure of T strain live Babesia bovis vaccine. Aust Vet J 1995, 72(8):296-300. 10.1111/j.1751-0813.1995.tb03558.x, 8579560.
16. Levy MG, Ristic M. Babesia bovis: continuous cultivation in a microaerophilous stationary phase culture. Science 1980, 207(4436):1218-1220. 10.1126/science.7355284, 7355284.
17. Hines SA, McElwain TF, Buening GM, Palmer GH. Molecular characterization of Babesia bovis merozoite surface proteins bearing epitopes immunodominant in protected cattle. Mol Biochem Parasitol 1989, 37(1):1-9. 10.1016/0166-6851(89)90096-0, 2482443.
18. Lau AO, Cereceres K, Palmer GH, Fretwell DL, Pedroni MJ, Mosqueda J, McElwain TF. Genotypic diversity of merozoite surface antigen 1 of Babesia bovis within an endemic population. Mol Biochem Parasitol 2010, 172(2):107-112. 10.1016/j.molbiopara.2010.03.017, 2941823, 20371255.
19. Altschul SF, Gish W, Miller W, Myers EW, Lipman DJ. Basic local alignment search tool. J Mol Biol 1990, 215(3):403-410.
20. Rissman AI, Mau B, Biehl BS, Darling AE, Glasner JD, Perna NT. Reordering contigs of draft genomes using the Mauve aligner. Bioinformatics 2009, 25(16):2071-2073. 10.1093/bioinformatics/btp356, 2723005, 19515959.
21. Darling AC, Mau B, Blattner FR, Perna NT. Mauve: multiple alignment of conserved genomic sequence with rearrangements. Genome Res 2004, 14(7):1394-1403. 10.1101/gr.2289704, 442156, 15231754.
22. Delcher AL, Phillippy A, Carlton J, Salzberg SL. Fast algorithms for large-scale genome alignment and comparison. Nucleic Acids Res 2002, 30(11):2478-2483. 10.1093/nar/30.11.2478, 117189, 12034836.
23. Huang X, Madan A. CAP3: A DNA sequence assembly program. Genome Res 1999, 9(9):868-877. 10.1101/gr.9.9.868, 310812, 10508846.
24. Ng PC, Henikoff S. Predicting deleterious amino acid substitutions. Genome Res 2001, 11(5):863-874. 10.1101/gr.176601, 311071, 11337480.
25. Mangold AJ, Vanzini VR, Echaide IE, de Echaide ST, Volpogni MM, Guglielmone AA. Viability after thawing and dilution of simultaneously cryopreserved vaccinal Babesia bovis and Babesia bigemina strains cultured in vitro. Vet Parasitol 1996, 61(3-4):345-348. 10.1016/0304-4017(95)00839-X, 8720572.
26. Somerville RP, Littlebury P, Pipano E, Brown CG, Shkap V, Adamson RE, Oliver RA, Glass EJ, Hall FR. Phenotypic and genotypic alterations associated with the attenuation of a Theileria annulata vaccine cell line from Turkey. Vaccine 1998, 16(6):569-575. 10.1016/S0264-410X(97)84509-4, 9569467.
27. Yano K, Nakabayashi T. Attenuation of the virulent RH strain of Toxoplasma gondii by passages in mice immunized with Toxoplasma lysate antigens. Biken J 1986, 29(2):31-37.
28. Schmidt LH, Fradkin R, Sesler C, Squires W, Zeyen P. Attenuation of the virulence of the M strain of Plasmodium cynomolgi during prolonged multiplication in splenectomized rhesus monkeys. Am J Trop Med Hyg 1987, 37(3):460-490.
29. Van Schaik W, Top J, Riley DR, Boekhorst J, Vrijenhoek JE, Schapendonk CM, Hendrickx AP, Nijman IJ, Bonten MJ, Tettelin H, et al. Pyrosequencing-based comparative genome analysis of the nosocomial pathogen Enterococcus faecium and identification of a large transferable pathogenicity island. BMC Genomics 11:239.
30. Tauch A, Schneider J, Szczepanowski R, Tilker A, Viehoever P, Gartemann KH, Arnold W, Blom J, Brinkrolf K, Brune I, et al. Ultrafast pyrosequencing of Corynebacterium kroppenstedtii DSM44385 revealed insights into the physiology of a lipophilic corynebacterium that lacks mycolic acids. J Biotechnol 2008, 136(1-2):22-30. 10.1016/j.jbiotec.2008.03.004, 18430482.
31. Hall R, Ilhan T, Kirvar E, Wilkie G, Preston PM, Darghouth M, Somerville R, Adamson R. Mechanism(s) of attenuation of Theileria annulata vaccine cell lines. Trop Med Int Health 1999, 4(9):A78-84. 10.1046/j.1365-3156.1999.00454.x, 10540315.
32. Doolan DL, Dobano C, Baird JK. Acquired immunity to malaria. Clin Microbiol Rev 2009, 22(1):13-36. Table of Contents, 10.1128/CMR.00025-08, 2620631, 19136431.
33. Langhorne J, Ndungu FM, Sponaas AM, Marsh K. Immunity to malaria: more questions than answers. Nat Immunol 2008, 9(7):725-732. 10.1038/ni.f.205, 18563083.
34. Rask TS, Hansen DA, Theander TG, Gorm Pedersen A, Lavstsen T. Plasmodium falciparum erythrocyte membrane protein 1 diversity in seven genomes--divide and conquer. PLoS Comput Biol 2010, 6(9).
35. Colinet D, Schmitz A, Cazes D, Gatti JL, Poirie M. The origin of intraspecific variation of virulence in an eukaryotic immune suppressive parasite. PLoS Pathog 6(11):e1001206.
36. Iyer JK, Amaladoss A, Genesan S, Preiser PR. Variable expression of the 235 kDa rhoptry protein of Plasmodium yoelii mediate host cell adaptation and immune evasion. Mol Microbiol 2007, 65(2):333-346. 10.1111/j.1365-2958.2007.05786.x, 17590237.
37. May FJ, Li L, Davis CT, Galbraith SE, Barrett AD. Multiple pathways to the attenuation of West Nile virus in South-East Texas in 2003. Virology 2010, 405(1):8-14. 10.1016/j.virol.2010.04.022, 20580395.
38. Broadbent K, Park D, Wolf AR, Van Tyne D, Sims JS, Ribacke U, Volkman S, Duraisingh M, Wirth D, Sabeti PC, et al. A global transcriptional analysis of Plasmodium falciparum malaria reveals a novel family of telomere-associated lncRNAs. Genome Biol 12(6):R56.