Use of affinity-directed liquid chromatography-mass spectrometry to map the epitopes of a factor VIII inhibitor antibody fraction

Journal of Thrombosis and Haemostasis

Volumn 9, Issue 8, 2011, Pages 1534-1540

  Griffiths, A E ^a   Wang, W ^a   Hagen, F K ^a   Fay, Philip J ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

Epitope mapping; Factor VIII; Inhibitor plasma; Mass spectrometry

Indexed keywords

BLOOD CLOTTING FACTOR 8 INHIBITOR; EPITOPE; IMMUNOGLOBULIN G;

AMINO ACID SEQUENCE; ANTIGEN ANTIBODY REACTION; ARTICLE; CONTROLLED STUDY; HEMOPHILIA A; HUMAN; IMMUNOPRECIPITATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION;

AMINO ACID SEQUENCE; ANTIBODIES, NEUTRALIZING; BINDING SITES; CHROMATOGRAPHY, AFFINITY; CHROMATOGRAPHY, REVERSE-PHASE; EPITOPE MAPPING; FACTOR VIII; HUMANS; IMMUNODOMINANT EPITOPES; IMMUNOPRECIPITATION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDE MAPPING; PROTEIN CONFORMATION; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN INTERACTION MAPPING; TANDEM MASS SPECTROMETRY;

EID: 80051590025     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2011.04397.x     Document Type: Article

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