Synthesis and Evaluation of Antimalarial Activity of Oxygenated 3-alkylpyridine Marine Alkaloid Analogues

Chemical Biology and Drug Design

Volumn 78, Issue 3, 2011, Pages 477-482

  Hilário, Flaviane F ^a   de Paula, Renata Cristina ^b   Silveira, Mariana L T ^a   Viana, Gustavo H R ^b   Alves, Rosemeire B ^a   Pereira, Juliana R C S ^b,c   Silva, Luciana Maria ^c   de Freitas, Rossimiriam P ^a   de Pilla Varotti, Fernando ^b  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^c FUNDAÇÃO EZEQUIEL DIAS   (Brazil)

Author keywords

3 alkylpyridines; Malaria; Marine alkaloids

Indexed keywords

1 NONANAMINE, 9 (3 PYRIDINYLPROPOXY); 1,1 DIMETHYLETHYL[12 (3 PYRIDINYLPROPOXY)DODECYL]CARBAMATE; 12 [3 (PYRIDIN 3 YL)PROPOXY]DODECAN 1 AMINE; 3 [3 (12 AZIDODODECYLOXY)PROPYL]PYRIDINE; 3 PYRIDINEPROPANOL; ALKALOID DERIVATIVE; CHLOROQUINE; METHYL N(1,1 DIMETHYLETHOXYCARBONYL)N[9 [3 (3 PYRIDINYL)PROPOXY]NONYL]BETA ALANINATE; METHYL N[9 [3 (3 PYRIDINYL)PROPOXY]NONYL]BETA ALANINATE; PROPANOL; PYRIDINIUM, 3 [3 [9 [(1,1 DIMETHYLETHOXYCARBONYL)(3 METHOXY 3 OXOPROPYLAMINO)]NONYLOXY]PROPYL] 1 (PHENYLMETHYL), CHLORIDE; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; CELL CULTURE; CYTOTOXICITY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LETTER; NONHUMAN; PARASITEMIA; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; WILLIAMSON REACTION;

ALKALOIDS; ANTIMALARIALS; CELL LINE; CELL SURVIVAL; HUMANS; MALARIA, FALCIPARUM; PLASMODIUM FALCIPARUM; PYRIDINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 80051586053     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2011.01154.x     Document Type: Letter

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