메뉴 건너뛰기




Volumn 79, Issue 9, 2011, Pages 2684-2692

Structural analysis of the N-terminal fragment of the antiangiogenic protein endostatin: A molecular dynamics study

Author keywords

Angiogenesis; Cancer; Endostatin; Molecular dynamics; Peptide structure

Indexed keywords

ANGIOGENESIS INHIBITOR; CANSTATIN; COLLAGEN TYPE 4; ENDOSTATIN; INTEGRIN; METICRANE; ZINC;

EID: 80051565429     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.23096     Document Type: Article
Times cited : (15)

References (36)
  • 1
    • 0026639806 scopus 로고
    • Angiogenesis
    • Folkman J, Shing Y. Angiogenesis. J Biol Chem 1992; 267: 10931-10934.
    • (1992) J Biol Chem , vol.267 , pp. 10931-10934
    • Folkman, J.1    Shing, Y.2
  • 3
    • 0001033082 scopus 로고
    • Isolation and sequencing of cDNAs for proteins with multiple domains of gly-xaa-yaa repeats identify a distinct family of collagenous proteins
    • Oh SP, Kamagata Y, Muragaki Y, Timmons S, Ooshima A, Olsen BR. Isolation and sequencing of cDNAs for proteins with multiple domains of gly-xaa-yaa repeats identify a distinct family of collagenous proteins. Proc Natl Acad Sci USA 1994; 91: 4229-4233.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 4229-4233
    • Oh, S.P.1    Kamagata, Y.2    Muragaki, Y.3    Timmons, S.4    Ooshima, A.5    Olsen, B.R.6
  • 4
    • 0037442551 scopus 로고    scopus 로고
    • Human endostatin-derived synthetic peptides possess potent antiangiogenic properties in vitro and in vivo
    • Cattaneo MG, Pola S, Francescato PE, Chillemi F, Vicentini LM. Human endostatin-derived synthetic peptides possess potent antiangiogenic properties in vitro and in vivo. Exp Cell Res 2003; 283: 230-236.
    • (2003) Exp Cell Res , vol.283 , pp. 230-236
    • Cattaneo, M.G.1    Pola, S.2    Francescato, P.E.3    Chillemi, F.4    Vicentini, L.M.5
  • 5
    • 0141455068 scopus 로고    scopus 로고
    • Studies on the structure-activity relationship of endostatin: synthesis of human endostatin peptides exhibiting potent antiangiogenic activities
    • Francescato P, Chillemi F, Rag E, Cattaneo MG, Pola S, Vicentini L. Studies on the structure-activity relationship of endostatin: synthesis of human endostatin peptides exhibiting potent antiangiogenic activities. J Med Chem 2003; 46: 4165-4172.
    • (2003) J Med Chem , vol.46 , pp. 4165-4172
    • Francescato, P.1    Chillemi, F.2    Rag, E.3    Cattaneo, M.G.4    Pola, S.5    Vicentini, L.6
  • 6
    • 0141809387 scopus 로고    scopus 로고
    • Angiossupressive and angiostimulatory effects exerted by synthetic partial sequences of endostatin
    • Morbidelli L, Donnini S, Chillemi F, Giachetti A, Ziche M. Angiossupressive and angiostimulatory effects exerted by synthetic partial sequences of endostatin. Clin Cancer Res 2003; 9: 5358-5369.
    • (2003) Clin Cancer Res , vol.9 , pp. 5358-5369
    • Morbidelli, L.1    Donnini, S.2    Chillemi, F.3    Giachetti, A.4    Ziche, M.5
  • 7
    • 2442555007 scopus 로고    scopus 로고
    • An endostatin-derived peptide interacts with integrins and regulates actin cytoskeleton and migrtion of endothelial cells
    • Wickström SA, Alitalo K, Keski-Oja J. An endostatin-derived peptide interacts with integrins and regulates actin cytoskeleton and migrtion of endothelial cells. J Biol Chem 2004; 279: 20178-20185.
    • (2004) J Biol Chem , vol.279 , pp. 20178-20185
    • Wickström, S.A.1    Alitalo, K.2    Keski-Oja, J.3
  • 9
    • 30344431813 scopus 로고    scopus 로고
    • Short synthetic endostatin peptides inhibit endothelial migration in vitro and endometriosis in a mouse model
    • Becker CM, Sampson DA, Short SM, Javaherian K, Folkman J, D'amato RJ. Short synthetic endostatin peptides inhibit endothelial migration in vitro and endometriosis in a mouse model. Fertil Steril 2006; 85: 71-77.
    • (2006) Fertil Steril , vol.85 , pp. 71-77
    • Becker, C.M.1    Sampson, D.A.2    Short, S.M.3    Javaherian, K.4    Folkman, J.5    D'amato, R.J.6
  • 11
    • 0031469819 scopus 로고    scopus 로고
    • Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance
    • Boehm T, Folkman J, Browder T, O'Reilly MS. Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance. Nature 1997; 390: 404-407.
    • (1997) Nature , vol.390 , pp. 404-407
    • Boehm, T.1    Folkman, J.2    Browder, T.3    O'Reilly, M.S.4
  • 19
    • 0020997912 scopus 로고
    • Dictionary of protein secondary structure: pattern recognition of hydrogen bonded and geometrical features
    • Kabsch W, Sanders C. Dictionary of protein secondary structure: pattern recognition of hydrogen bonded and geometrical features. Biopolymers 1983; 22: 2577-2637.
    • (1983) Biopolymers , vol.22 , pp. 2577-2637
    • Kabsch, W.1    Sanders, C.2
  • 22
    • 33749020839 scopus 로고    scopus 로고
    • Piper: an fft-based protein docking program with pairwise potentials
    • Kozakov D, Brenke R, Comeau SR, Vajda S. Piper: an fft-based protein docking program with pairwise potentials. Proteins 2006; 65: 392-406.
    • (2006) Proteins , vol.65 , pp. 392-406
    • Kozakov, D.1    Brenke, R.2    Comeau, S.R.3    Vajda, S.4
  • 23
    • 0345832301 scopus 로고    scopus 로고
    • Cluspro: an automated docking and discrimination method for the prediction of protein complexes
    • Comeau SR, Gatchell DW, Vajda S, Camacho CJ. Cluspro: an automated docking and discrimination method for the prediction of protein complexes. Bioinformatics 2004; 20: 45-50.
    • (2004) Bioinformatics , vol.20 , pp. 45-50
    • Comeau, S.R.1    Gatchell, D.W.2    Vajda, S.3    Camacho, C.J.4
  • 24
    • 3242877815 scopus 로고    scopus 로고
    • Cluspro: a fully automated algorithm for protein-protein docking
    • Comeau SR, Gatchell DW, Vajda S, Camacho CJ. Cluspro: a fully automated algorithm for protein-protein docking. Nucleic Acids Res 2004; 32 (Suppl 2): W96-W99.
    • (2004) Nucleic Acids Res , vol.32 , Issue.SUPPL. 2
    • Comeau, S.R.1    Gatchell, D.W.2    Vajda, S.3    Camacho, C.J.4
  • 26
    • 18344390410 scopus 로고    scopus 로고
    • The 1.9-Å crystal structure of the noncollagenous (nc1) domain of human placenta collagen IV shows stabilization via a novel type of covalent met-lys cross-link
    • Than ME, Henrich S, Huber R, Ries A, Mann K, Kühn K, Timpl R, Bourenkov GP, Bartunik HD, Bode W. The 1.9-Å crystal structure of the noncollagenous (nc1) domain of human placenta collagen IV shows stabilization via a novel type of covalent met-lys cross-link. Proc Natl Acad Sci USA 2002; 99: 6607-6612.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 6607-6612
    • Than, M.E.1    Henrich, S.2    Huber, R.3    Ries, A.4    Mann, K.5    Kühn, K.6    Timpl, R.7    Bourenkov, G.P.8    Bartunik, H.D.9    Bode, W.10
  • 31
    • 54449094358 scopus 로고    scopus 로고
    • Identification of amino acids essential for the antiangiogenic activity of tumstatin and its use in combination antitumor activity
    • Eikesdal HP, Sugimoto H, Birrane G, Maeshima Y, Cooke VG, Kieran M, Kalluri R. Identification of amino acids essential for the antiangiogenic activity of tumstatin and its use in combination antitumor activity. Proc Natl Acad Sci USA 2008; 105: 15040-15045.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 15040-15045
    • Eikesdal, H.P.1    Sugimoto, H.2    Birrane, G.3    Maeshima, Y.4    Cooke, V.G.5    Kieran, M.6    Kalluri, R.7
  • 32
    • 0344983831 scopus 로고    scopus 로고
    • Canstatin-n fragment inhibits in vitro endothelial cell proliferation and suppresses in vivo tumor growth
    • He GA, Luo JX, Zhang TY, Wang FY, Li RF. Canstatin-n fragment inhibits in vitro endothelial cell proliferation and suppresses in vivo tumor growth. BBRC 2003; 312: 801-805.
    • (2003) BBRC , vol.312 , pp. 801-805
    • He, G.A.1    Luo, J.X.2    Zhang, T.Y.3    Wang, F.Y.4    Li, R.F.5
  • 33
    • 54149116062 scopus 로고    scopus 로고
    • Characterization of the antia-angiogenic properties of arresten, an α1β1 integrin-dependent collagen-derived tumor suppressor
    • Nyberg P, Xie L, Sugimoto H, Colorado P, Sund M, Holthaus K, Sudhakar A, Salo T, Kalluri R. Characterization of the antia-angiogenic properties of arresten, an α1β1 integrin-dependent collagen-derived tumor suppressor. Exp Cell Res 2008; 314: 3292-3305.
    • (2008) Exp Cell Res , vol.314 , pp. 3292-3305
    • Nyberg, P.1    Xie, L.2    Sugimoto, H.3    Colorado, P.4    Sund, M.5    Holthaus, K.6    Sudhakar, A.7    Salo, T.8    Kalluri, R.9
  • 34
    • 20144374161 scopus 로고    scopus 로고
    • Canstatin acts on endothelial and tumor cells via mitochondrial damage initiated through interaction with αvβ3 and αvβ5 integrins
    • Magnon C, Galaup A, Mullan B, Rouffiac V, Bidart JM, Griscelli F, Opolon P, Perricaudet M. Canstatin acts on endothelial and tumor cells via mitochondrial damage initiated through interaction with αvβ3 and αvβ5 integrins. Cancer Res 2005; 65: 4353-4361.
    • (2005) Cancer Res , vol.65 , pp. 4353-4361
    • Magnon, C.1    Galaup, A.2    Mullan, B.3    Rouffiac, V.4    Bidart, J.M.5    Griscelli, F.6    Opolon, P.7    Perricaudet, M.8
  • 36
    • 47349107672 scopus 로고    scopus 로고
    • Research advances of endostatin and its short internal fragments
    • Xu HL, Tan HN, Wang FS, Tang W. Research advances of endostatin and its short internal fragments. Curr Prot Pept Sci 2008; 9: 275-283.
    • (2008) Curr Prot Pept Sci , vol.9 , pp. 275-283
    • Xu, H.L.1    Tan, H.N.2    Wang, F.S.3    Tang, W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.