Oral LD50 toxicity modeling and prediction of per-and polyfluorinated chemicals on rat and mouse

Molecular Diversity

Volumn 15, Issue 2, 2011, Pages 467-476

  Bhhatarai, Barun ^a   Gramatica, Paola ^a  

^a UNIVERSITY OF INSUBRIA   (Italy)

Author keywords

Oral LD50; Perfluorinated chemicals; QSAR; REACH; Rodents; Toxicity

Indexed keywords

PERFLUORO COMPOUND; PERFLUOROOCTANESULFONIC ACID; PERFLUOROOCTANOIC ACID; FLUORINE DERIVATIVE;

ARTICLE; CHEMOMETRIC ANALYSIS; COMPUTER MODEL; GENETIC ALGORITHM; LD 50; MULTIPLE LINEAR REGRESSION ANALYSIS; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RISK ASSESSMENT; TOXICITY TESTING; ALGORITHM; ANIMAL; CHEMISTRY; INHALATIONAL DRUG ADMINISTRATION; MOUSE; ORAL DRUG ADMINISTRATION; RAT; REPRODUCIBILITY; THEORETICAL MODEL;

ADMINISTRATION, INHALATION; ADMINISTRATION, ORAL; ALGORITHMS; ANIMALS; FLUORINE COMPOUNDS; LETHAL DOSE 50; MICE; MODELS, THEORETICAL; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RATS; REPRODUCIBILITY OF RESULTS;

EID: 80051558390     PISSN: 13811991     EISSN: 1573501X     Source Type: Journal    
DOI: 10.1007/s11030-010-9268-z     Document Type: Article

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