Alpha1 receptor antagonist in the median raphe nucleus evoked hyperphagia in free-feeding rats

Appetite

Volumn 57, Issue 2, 2011, Pages 498-503

  Mansur, Samira Schultz ^a   Terenzi, Mariana Graciela ^a   Neto, José Marino ^a   Faria, Moacir Serralvo ^a   Paschoalini, Marta Aparecida ^a  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

Author keywords

adrenergic receptor; Food intake; Median raphe nucleus; Prazosin; Yohimbine

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA 2 ADRENERGIC RECEPTOR; CLONIDINE; PHENYLEPHRINE; PRAZOSIN; YOHIMBINE; ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT;

ALPHA ADRENERGIC RECEPTOR BLOCKING; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FEEDING BEHAVIOR; FLUID INTAKE; FOOD INTAKE; HYPERPHAGIA; LATENT PERIOD; MALE; MEDIAN RAPHE NUCLEUS; NONHUMAN; RAT; SEROTONINERGIC NERVE CELL; ANIMAL; CYTOLOGY; DRUG EFFECT; EATING; PATHOLOGY; RAPHE NUCLEUS; WISTAR RAT;

ADRENERGIC ALPHA-1 RECEPTOR ANTAGONISTS; ADRENERGIC ALPHA-2 RECEPTOR ANTAGONISTS; ANIMALS; EATING; FEEDING BEHAVIOR; HYPERPHAGIA; MALE; PRAZOSIN; RAPHE NUCLEI; RATS; RATS, WISTAR; SEROTONERGIC NEURONS; YOHIMBINE;

EID: 80051553609     PISSN: 01956663     EISSN: 10958304     Source Type: Journal    
DOI: 10.1016/j.appet.2011.06.017     Document Type: Article

References (38)

1. Adell A., Artigas F. Regulation of the release of 5-hydroxytryptamine in the median raphe nucleus of the rat by catecholaminergic afferents. European Journal of Neuroscience 1999, 11:2305-2311.
2. Adell A., Celada P., Teresa Abellán M., Artigas F. Origin and functional role of the extracellular serotonin in the midbrain raphe nuclei. Brain Research Reviews 2002, 39:154-180.
3. Andrews N., Hogg S., Gonzalez L.E., File S.E. 5-HT1A receptors in the median raphe nucleus of dorsal hippocampus may mediate anxiolytic and anxiogenic behaviours respectively. European Journal of Pharmacology 1994, 264:259-264.
4. 1A autoreceptors in the raphe nucleus disrupts the contextual conditioning in rats. Behavioural Brain Research 2001, 126:175-184.
5. Bonvento G., Scatton B., Claustre Y., Rouquier L. Effect of local injection of 8-OH-DPAT into the dorsal or median raphe nuclei on extracellular levels of serotonin in serotonergic projection areas in the rat brain. Neuroscience Letters 1992, 132:101-104.
6. Bortolozzi A., Artigas F. Control of 5-hydroxytryptamine release in the dorsal raphe nucleus by the noradrenergic system in rat brain. Role of α-adrenoreceptors. Neuropsychopharmacology 2003, 28:421-434.
7. Cryan J.F., Page M.E., Lucki I. Noradrenergic lesions differentially alter the antidepressant-like effects of reboxetine in a modified forced swim test. European Journal of Pharmacology 2002, 436:197-205.
8. Currie P.J., Coscina D.V. Diurnal variations in the feeding response to 8-OHDPAT injected into the dorsal or median raphe. Neuro Report 1993, 4:1105-1107.
9. Currie P.J., Fletcher P.J., Coscina D.V. Administration of 8-OH-DPAT into the midbrain raphe nuclei. Effects on medial hypothalamic NE-induced feeding. American Journal of Physiology 1994, 266:1645-1651.
10. Descarries L., Watckins K.C., Garcia S., Beaudet A. The serotonin neurons in nucleus raphe dorsalis of adult rat. A light and electron microscope radioautographic study. Journal of Comparative Neurology 1982, 201:239-254.
11. Dos Santos R.L.D., Mansur S.S., Steffens S.M., Faria M.S., Marino Neto J., Paschoalini M.A. Food intake increased after injection of adrenaline into the median raphe nucleus of free-feeding rats. Behavioural Brain Research 2009, 197:411-416.
12. Fletcher P.J. Dopamine receptor blockade in nucleus accumbens or caudate nucleus differentially affects feeding induced by 8-OH-DPAT injected into dorsal or median raphe. Brain Research 1991, 552:181-189.
13. Fletcher P.J., Coscina D.V. Injecting 5-HT into the PVN does not prevent feeding induced by injecting 8-OH-DPAT into the raphe. Pharmacology Biochemistry and Behavior 1993, 46:487-491.
14. Funk D., Li Z., Fletcher J., Le A.D. Effects of injections of 8-hydroxy-2-(di-npropylamino) tetralin or muscimol in the median raphe nucleus on c-fos mRNA in the rat brain. Neuroscience 2005, 131:475-479.
15. Haider S., Haleem D.J. Decreases of brain serotonin following a food restriction schedule of 4 weeks in male and female rats. Medical Science Monitor 2000, 6:1061-1067.
16. Hensler J.G. Serotonergic modulation of the limbic system. Neuroscience and Biobehavioral Reviews 2006, 30:203-214.
17. 2 adrenoceptors. Neuropharmacology 2001, 41:433-442.
18. Judge S.J., Young R.L., Gartside S. GABA-A receptor modulation of 5-HT neuronal firing in the median raphe nucleus. Implications for the action of anxiolytics. European Neuropsychopharmacology 2006, 16:612-619.
19. Kang M., Park C., Ahn H., Huh Y. Ectopic expression of serotonin-positive neurons in the hypothalamus associated with a significant serotonin decrease in the midbrain of food restricted rats. Neuroscience Letters 2001, 314:25-28.
20. Kaye W. Neurobiology of anorexia and bulimia nervosa. Physiology & Behavior 2008, 94:121-135.
21. Kelley A.E., Baldo B.A., Pratt W.E., Will M.J. Corticostriatal-hypothalamic circuitry and food motivation. Integration of energy, action and reward. Physiology & Behavior 2005, 86:773-795.
22. 1A receptors in the rat central nervous system. Journal of Comparative Neurology 1996, 365:289-305.
23. Leger L., Wiklund L. Distribution and numbers of indoleamine cell bodies in the cat brainstem determined with Falck-Hillarp fluorescence histochemistry. Brain Research Bulletin 1982, 9:245-251.
24. B agonist microinjections into medial accumbens shell increase feeding and induce anxiolysis in an animal model of anxiety. Behavioural Brain Research 2007, 184:142-149.
25. 1B, and serotonin transporter expression across the anteroposterior axis of the rat dorsal and median raphe nuclei. Journal of Comparative Neurology 2006, 498:611-623.
26. Maidel S., Lucinda A.M., Aquino V.W., Faria M.S., Paschoalini M.A. The adrenaline microinjection into the median raphe nucleus induced hypophagic effect in rats submitted to food restriction regimen. Neuroscience Letters 2007, 422:123-127.
27. Mansur S.S., Terenzi M.G., Marino-Neto J., Faria M.S., Paschoalini M.A. Changes in food intake and anxiety-like behaviors after clonidine injected into the median raphe nucleus. Behavioural Brain Research 2010, 212:71-77.
28. Mansur S.S., Terenzi M.G., Marino-Neto J., Faria M.S., Paschoalini M.A. Phenylephrine into the median raphe nucleus evokes an anxiolytic-like effect in free-feeding rats but does not alter food intake in free feeding rats. Behavioural Brain Research 2011, 217:209-214.
29. Mokler D.J., Dugal J.R., Hoffman J.M., Morgane P.J. Functional interrelations between nucleus raphé dorsalis and nucleus raphé medianus. A dual probe microdialysis study of glutamate-stimulated serotonin release. Brain Research Bulletin 2009, 78:132-138.
30. Ottoni E.B. Etholog 2.2. A tool for the transcription and timing of behavior observation sessions. Behavior Research Methods Instruments & Computers 2000, 32:446-449.
31. Paxino G., Watson C. The rat brain in stereotaxic coordinates 2007, Academic Press, San Diego, pp. 463. 6th ed.
32. Prat W.E., Blackstone K., Connolly M.E., Skelly M.J. Selective serotonin receptor stimulation of the medial nucleus accumbens causes differential effects on food intake and locomotion. Behavioral Neuroscience 2009, 23:1046-1057.
33. Shim I., Javaid J., Wirtshafter D. Dissociation of hippo-campal serotonin release and locomotor activity following pharmacological manipulations of the median raphe nucleus. Behavioural Brain Research 1997, 89:191-198.
34. 1A autoreceptors on serotonergic neurons in the midbrain raphe nuclei. European Journal of Neuroscience 1990, 2:1144-1154.
35. Takase L.F., Nogueira M.I. Patterns of Fos activation in rat raphe nuclei during feeding behavior. Brain Research 2008, 1200:10-18.
36. Walther D.J., Bader M. A unique central tryptophan hydroxylase isoform. Biochemical Pharmacology 2003, 66:1673-1680.
37. Wirtshafter D. The control of ingestive behavior by the median raphe nucleus. Appetite 2001, 36:99-10561.
38. Yada M.M., de Paula P.M., Menani J.V., Renzi A., Camargo L.A., Saad W.A., et al. Receptor-mediated effects of clonidine on need-induced 3% NaCl and water intake. Brain Research Bulletin 1997, 42:205-209.