Controlling multipotent stromal cell migration by integrating "course-graining" materials and "fine-tuning" small molecules via decision tree signal-response modeling

Biomaterials

Volumn 32, Issue 30, 2011, Pages 7524-7531

  Wu, Shan ^a   Wells, Alan ^b   Griffith, Linda G ^a   Lauffenburger, Douglas A ^a  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Cell migration; Computational modeling; Epidermal growth factor; Extracellular matrix; Mesenchymal stem cells

Indexed keywords

CELL MIGRATION; COMPUTATIONAL MODELING; EPIDERMAL GROWTH FACTOR; EXTRACELLULAR MATRICES; MESENCHYMAL STEM CELL;

BIOMIMETIC MATERIALS; BIOMIMETICS; CELL CULTURE; DECISION TREES; ESTERS; ETHYLENE; FLOWCHARTING; MOLECULES; PEPTIDES; PLANT EXTRACTS; POLYETHYLENE OXIDES; REFORESTATION; STEM CELLS; SUBSTRATES; TISSUE;

SCAFFOLDS (BIOLOGY);

COLLAGEN TYPE 1; EPIDERMAL GROWTH FACTOR; FIBRONECTIN; FOCAL ADHESION KINASE; MACROGOL; MITOGEN ACTIVATED PROTEIN KINASE; POLY(METHYL METHACRYLATE); PROTEIN KINASE B; TELOMERASE REVERSE TRANSCRIPTASE; VASCULOTROPIN; VITRONECTIN;

ADSORPTION; ARTICLE; BIOMIMETICS; CELL IMMORTALIZATION; CELL MIGRATION; CELL MOTILITY; DECISION TREE; ENZYME SUBSTRATE; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; MULTIPOTENT STEM CELL; PRIORITY JOURNAL; STROMA CELL; SURFACE PROPERTY; VELOCITY;

BIOCOMPATIBLE MATERIALS; CELL LINE; CELL MOVEMENT; COMPUTER SIMULATION; DECISION TREES; EPIDERMAL GROWTH FACTOR; EXTRACELLULAR MATRIX; HUMANS; MESENCHYMAL STEM CELLS; MODELS, BIOLOGICAL; MULTIPOTENT STEM CELLS;

EID: 80051550133     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.06.050     Document Type: Article

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