Marrow-Derived stem cell motility in 3D synthetic scaffold is governed by geometry along with adhesivity and stiffness

Biotechnology and Bioengineering

Volumn 108, Issue 5, 2011, Pages 1181-1193

  Peyton, Shelly R ^a   Kalcioglu, Z Ilke ^a   Cohen, Joshua C ^a   Runkle, Anne P ^a   Van Vliet, Krystyn J ^a   Lauffenburger, Douglas A ^a,b   Griffith, Linda G ^a  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Hydrogel scaffold; Mesenchymal stem cell; Migration; Poly(ethylene oxide)

Indexed keywords

3D SCAFFOLDS; ADHESIVITY; CELL DIAMETERS; CELL MIGRATION; CELL MOVEMENT; CLINICAL APPLICATION; CONNECTIVE TISSUES; HYDROGEL SCAFFOLDS; INVERSE OPAL; MARROW-DERIVED STEM CELLS; MATRIX; MESENCHYMAL STEM CELL; MIGRATION; PORE DIAMETERS; PROCESSING TECHNIQUE; PROGENITOR CELL; SPHERICAL CELLS; SYNTHETIC SCAFFOLDS; TEMPLATING; TISSUE INTEGRATION; TOTAL PATH LENGTH; TUNABLE PARAMETER;

CELL CULTURE; ELASTIC MODULI; ETHYLENE; ETHYLENE GLYCOL; HYDROGELS; JOINTS (ANATOMY); MOLECULAR WEIGHT; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; STEM CELLS; STIFFNESS; STIFFNESS MATRIX; THREE DIMENSIONAL;

SCAFFOLDS (BIOLOGY);

MACROGOL; TISSUE SCAFFOLD;

ADHESION; ARTICLE; CELL MIGRATION; CELL MOTILITY; CELL MOTION; CELL SIZE; CROSS LINKING; HEMATOPOIETIC STEM CELL; MESENCHYMAL STEM CELL; POROSITY; PROCESSING; RIGIDITY; STEM CELL; YOUNG MODULUS;

CELL ADHESION; CELL LINE, TRANSFORMED; CELL MOVEMENT; HEMATOPOIETIC STEM CELLS; HUMANS;

EID: 79953127148     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.23027     Document Type: Article

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