Effect of Dehydrozingerone, a half analog of curcumin on dexamethasone-delayed wound healing in albino rats

Molecular and Cellular Biochemistry

Volumn 355, Issue 1-2, 2011, Pages 249-256

  Rao, Mallikarjuna C ^a   Sudheendra, Arun T ^a   Nayak, Pawan G ^a   Paul, Piya ^a   Kutty, Gopalan N ^a   Shenoy, Rekha R ^a  

^a MANIPAL COLLEGE OF PHARMACEUTICAL SCIENCES   (India)

Author keywords

Catalase; Dehydrozingerone; Dexamethasone; DNA; Hydroxyproline; Lysyl oxidase; Superoxide dismutase

Indexed keywords

CATALASE; COLLAGEN FIBER; CURCUMIN; DEHYDROZINGERONE; DEXAMETHASONE; GLUTATHIONE; HYDROGEN PEROXIDE; HYDROXYPROLINE; PROTEIN; PROTEIN LYSINE 6 OXIDASE; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; THIOL;

ALBINISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL STRAIN V 79; COMPARATIVE EFFECTIVENESS; CONTROLLED STUDY; DISEASE MODEL; DOSE RESPONSE; DRUG DOSAGE FORM COMPARISON; DRUG EFFECT; DRUG EFFICACY; FEMALE; GENERAL CONDITION IMPROVEMENT; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATORY CELL; MALE; NONHUMAN; OXIDATIVE STRESS; RAT; TENSILE STRENGTH; WOUND CLOSURE; WOUND HEALING IMPAIRMENT;

ANIMALS; ANTIOXIDANTS; CATALASE; CELL LINE; CRICETINAE; DEXAMETHASONE; DNA; DRUG STABILITY; ENZYME ASSAYS; GELS; GLUTATHIONE TRANSFERASE; GRANULATION TISSUE; HYDROXYPROLINE; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NITRIC OXIDE; PROTEIN-LYSINE 6-OXIDASE; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; RNA; SKIN; STYRENES; SUPEROXIDE DISMUTASE; TENSILE STRENGTH; WOUND HEALING;

RATTUS;

EID: 80051545403     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-011-0861-y     Document Type: Article

References (28)

1. Cotran RS, Kumar V, Robbins SL, Schoen FJ (1994) Inflammation and repair. In: Pathologic basis of disease, 5th edn. WB Saunders Company, Philadelphia
2. Frank S, Kampfer H (2003) Excisional wound healing: an experimental approach. In: DiPietro LA, Burns AL (eds) Methods in molecular biology: wound healing: methods and protocols. Humana Press, Totowa, pp 3-16
3. RAF Clark 1985 Cutaneous tissue repair: basic biologic considerations J Am Acad Dermatol 13 701 725 2416789 10.1016/S0190-9622(85)70213-7 1:STN:280:DyaL28%2Fos1GktQ%3D%3D (Pubitemid 16245140)
4. J Dissemond M Goos SN Wagner 2002 The role of oxidative stress in the pathogenesis and therapy of chronic wounds Der Hautzart 53 718 723 10.1007/s00105-001-0325-5 1:STN:280:DC%2BD38nkt1Ggsg%3D%3D (Pubitemid 36069821)
5. CM Rao KM George KL Bairy SN Somayaji 2000 An appraisal of healing profiles of oral and external (gel) metronidazole on partial thickness burn wound Indian J Pharmacol 32 282 287 1:CAS:528:DC%2BD3cXotlyrs74%3D
6. DV Rajakumar MN Rao 1994 Antioxidant properties of dehydrozingerone and curcumin in rat brain homogenates Mol Cell Biochem 140 73 79 7877600 10.1007/BF00928368 1:CAS:528:DyaK2MXivVSms7g%3D (Pubitemid 24379891)
7. VK Parihar J Dhawan S Kumar SN Manjula G Subramanian MK Unnikrishnan C Mallikarjuna Rao 2007 Free radical scavenging and radioprotective activity of dehydrozingerone against whole body gamma irradiation in Swiss albino mice Chem Biol Interact 170 49 58 17765885 10.1016/j.cbi.2007.07.006 1:CAS:528: DC%2BD2sXhtVCit77M (Pubitemid 47390694)
8. HP Ehrlich TK Hunt 1969 The effects of cortisone and anabolic steroids on the tensile strength of healing wounds Ann Surg 170 203 206 5796705 10.1097/00000658-196908000-00007 1:CAS:528:DyaF1MXkvFylt7g%3D
9. KH Lee 1968 Studies on the mechanism of action of salicylates II: retardation of wound healing by aspirin J Pharm Sci 57 1042 1043 5671327 10.1002/jps.2600570633 1:CAS:528:DyaF1cXkt1Kjsr0%3D
10. JJ Morton MH Malone 1972 Evaluation of vulnerary activity by an open procedure in rats Arch Int Pharmacodyn Ther 196 117 126 5059357 1:CAS:528:DyaE38XktVSltb8%3D
11. KH Lee TG Tong 1970 Mechanism of action of retinyl compounds on wound healing. II: effect of active retinyl derivatives on granuloma formation J Pharm Sci 59 1195 1197 5457346 10.1002/jps.2600590836 1:CAS:528:DyaE3cXkvVKgs7g%3D
12. Pearson H, Stirling D (2003) DNA extraction from tissue. In: Bartlett JMS, Stirling D (eds) Methods in molecular biology: PCR protocols, 2nd edn. Humana Press, Totowa, pp 33-34
13. SH Snyder ED Hendley 1971 Sensitive fluorometric and radiometric assays for monoamine oxidase and diamine oxidase Methods Enzymol 17B 741 746 10.1016/0076-6879(71)17129-7
14. RE Neuman MA Logan 1950 The determination of hydroxyproline J Biol Chem 186 299 306
15. K Hafer KS Iwamoto RH Schiestl 2008 Refinement of the dichlorofluorescein assay for flow cytometric measurement of reactive oxygen species in irradiated and bystander cell populations Radiat Res 169 460 468 18363435 10.1667/RR1212.1 1:CAS:528:DC%2BD1cXkt1aitrc%3D (Pubitemid 351620044)
16. YK Kim RG Kim SJ Park JH Ha JW Choi HJ Park, et al. 2002 In vitro antiinflammatory activity of kalopanaxsaponin A isolated from Kalopanax pictus in murine macrophage RAW 264.7 cells Biol Pharm Bull 25 472 476 11995927 10.1248/bpb.25.472 1:CAS:528:DC%2BD38XkslWrs7Y%3D (Pubitemid 40036737)
17. KA Kang R Zhang MJ Piao KH Lee BJ Kim SY Kim, et al. 2007 Inhibitory effects of glycitein on hydrogen peroxide induced cell damage by scavenging reactive oxygen species and inhibiting c-Jun N-terminal kinase Free Radic Res 41 720 729 17516245 10.1080/10715760701241618 1:CAS:528:DC%2BD2sXls1ShtLc%3D (Pubitemid 46845593)
18. H Aebi 1984 Catalase in vitro Methods Enzymol 105 121 126 6727660 10.1016/S0076-6879(84)05016-3 1:CAS:528:DyaL2cXltVKis7s%3D
19. HP Misra I Fridovich 1972 The role of superoxide anion in the auto-oxidation of epinephrine and a simple assay for superoxide dismutase J Biol Chem 247 3170 3175 4623845 1:CAS:528:DyaE38XhsFSntLk%3D
20. MA Moran JWD Pierre B Mannervick 1979 Levels of glutathione, glutathione reductase, glutathione-S-transferase activities in rat liver Biochim Biophys Acta 582 67 68
21. H Jennson P Alin B Mannervik 1985 Glutathione transferase isoenzymes from rat liver cytosol Methods Enzymol 113 504 507 10.1016/S0076-6879(85)13066-1 (Pubitemid 16195823)
22. LH Miao 1994 Measurement of protein thiol and glutathione in plasma Methods Enzymol 233 380 385 10.1016/S0076-6879(94)33044-1
23. WG Niehaus Jr B Samuelsson 1968 Formation of malonaldehyde from phospholipid arachidonate during microsomal lipid peroxidation Eur J Biochem 6 126 130 4387188 10.1111/j.1432-1033.1968.tb00428.x 1:CAS:528:DyaF1cXltVaqtL8%3D
24. PK Smith RI Krohn GT Hermanson AK Mallia FH Gartner MD Provenzano, et al. 1985 Measurement of bicinchoninic acid Anal Biochem 150 76 85 3843705 10.1016/0003-2697(85)90442-7 1:CAS:528:DyaL2MXlsFKksL0%3D (Pubitemid 16258399)
25. McManus JFA, Mowry RW (1965) Staining methods. Histological and histochemical. Harper & Row/Evanston, New York, p 423
26. LM Wahl SM Wahl SE Mergenhagen GR Martin 1974 Collagenase production by endotoxin-activated macrophages Proc Natl Acad Sci USA 71 3598 3601 4372628 10.1073/pnas.71.9.3598 1:CAS:528:DyaE2MXmvFSgsg%3D%3D
27. HP Ehrlich TM Krummel 1996 Regulation of wound healing from a connective tissue perspective Wound Repair Regen 4 203 210 17177814 10.1046/j.1524-475X. 1996.40206.x 1:STN:280:DC%2BD28jkt1ertA%3D%3D (Pubitemid 126674087)
28. MR Chinoy SE Zgleszewski RE Cilley TM Krummel 2000 Dexamethasone enhances ras-recision gene expression in cultured murine fetal lungs: role in development J Physiol Lung Cell Mol Physiol 279 312 318