Antiproliferative effect of chrysin on anaplastic thyroid cancer

Journal of Surgical Research

Volumn 170, Issue 1, 2011, Pages 84-88

  Phan, TramAnh ^a   Yu, Xiao Min ^a   Kunnimalaiyaan, Muthusamy ^a   Chen, Herbert ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

anaplastic thyroid cancer; apoptosis; chrysin; proliferation

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CASPASE 3; CHRYSIN; CYCLIN D1; CYTOCHROME C; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN MCL 1; X LINKED INHIBITOR OF APOPTOSIS;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CELL PROLIFERATION; CELL STRAIN HTH7; CELL STRAIN KAT18; CONTROLLED STUDY; DNA FINGERPRINTING; DRUG EFFECT; ENZYME DEGRADATION; HUMAN; HUMAN CELL; POORLY DIFFERENTIATED THYROID CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; TREATMENT OUTCOME; WESTERN BLOTTING;

APOPTOSIS; CASPASES; CELL LINE, TUMOR; CELL PROLIFERATION; FLAVONOIDS; HUMANS; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS C-BCL-2; THYROID NEOPLASMS; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 80051544050     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2011.03.064     Document Type: Article

References (23)

1. R.C. Smallridge, and J.A. Copland Anaplastic thyroid carcinoma: Pathogenesis and emerging therapies Clin Oncol (R Coll Radiol) 22 2010 486
2. R.L. Neff, W.B. Farrar, and R.T. Kloos Anaplastic thyroid cancer Endocrinol Metab Clin North Am 37 2008 525 xi
3. S.A. Hundahl, I.D. Fleming, and A.M. Fremgen A National Cancer Data Base report on 53,856 cases of thyroid carcinoma treated in the U.S., 1985-1995 [see comments] Cancer 83 1998 2638
4. W.R. Cornett, A.K. Sharma, and T.A. Day Anaplastic thyroid carcinoma: An overview Curr Oncol Rep 9 2007 152
5. B. Zarebczan, and H. Chen Multi-targeted approach in the treatment of thyroid cancer Minerva Chir 65 2010 59
6. S.N. Pinchot, R.S. Sippel, and H. Chen Multi-targeted approach in the treatment of thyroid cancer Ther Clin Risk Manag 4 2008 935
7. T. Zhang, X. Chen, and L. Qu Chrysin and its phosphate ester inhibit cell proliferation and induce apoptosis in HeLa cells Bioorg Med Chem 12 2004 6097
8. A. Monasterio, M.C. Urdaci, and I.V. Pinchuk Flavonoids induce apoptosis in human leukemia U937 cells through caspase-and caspase-calpain-dependent pathways Nutr Cancer 50 2004 90
9. B.Y. Khoo, S.L. Chua, and P. Balaram Apoptotic effects of chrysin in human cancer cell lines Int J Mol Sci 11 2010 2188
10. S.W. Fesik Promoting apoptosis as a strategy for cancer drug discovery Nat Rev Cancer 5 2005 876
11. R.E. Schweppe, J.P. Klopper, and C. Korch Deoxyribonucleic acid profiling analysis of 40 human thyroid cancer cell lines reveals cross-contamination resulting in cell line redundancy and misidentification J Clin Endocrinol Metab 93 2008 4331
12. M. Kunnimalaiyaan, M. Ndiaye, and H. Chen Apoptosis-mediated medullary thyroid cancer growth suppression by the PI3K inhibitor LY294002 Surgery 140 2006 1009 discussion 1014
13. F. Yin, A.E. Giuliano, and A.J. Van Herle Growth inhibitory effects of flavonoids in human thyroid cancer cell lines Thyroid 9 1999 369
14. S.J. Riedl, and Y. Shi Molecular mechanisms of caspase regulation during apoptosis Nat Rev Mol Cell Biol 5 2004 897
15. R. Krishnakumar, and W.L. Kraus The PARP side of the nucleus: Molecular actions, physiological outcomes, and clinical targets Mol Cell 39 2010 8
16. B.P. Eckelman, G.S. Salvesen, and F.L. Scott Human inhibitor of apoptosis proteins: Why XIAP is the black sheep of the family EMBO Rep 7 2006 988
17. L.W. Thomas, C. Lam, and S.W. Edwards Mcl-1: The molecular regulation of protein function FEBS Letters 584 2010 2981
18. E.A. Klein, and R.K. Assoian Transcriptional regulation of the cyclin D1 gene at a glance J Cell Sci 121 2008 3853
19. A. Saha, T. Kuzuhara, and N. Echigo Apoptosis of human lung cancer cells by curcumin mediated through up-regulation of "growth arrest and DNA damage inducible genes 45 and 153" Biol Pharm Bull 33 2010 1291
20. V. Manetto, R. Lorenzini, and C. Cordon-Cardo Bcl-2 and Bax expression in thyroid tumours: An immunohistochemical and Western blot analysis Virchows Arch 430 1997 125
21. Z.N. Oltval, C.L. Milliman, and S.J. Korsmeyer Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death Cell 74 1993 609
22. M.G. von Brandenstein, A. Ngum Abety, and R. Depping A p38-p65 transcription complex induced by endothelin-1 mediates signal transduction in cancer cells Biochim Biophys Acta 1783 2008 1613
23. K.J. Woo, Y.J. Jeong, and J.W. Park Chrysin-induced apoptosis is mediated through caspase activation and Akt inactivation in U937 leukemia cells Biochem Biophys Res Commun 325 2004 1215