Hydroxyisohexyl 3-cyclohexene carboxaldehyde (Lyral®) as allergen: Experience from a Contact Dermatitis Unit

Cutaneous and Ocular Toxicology

Volumn 30, Issue 3, 2011, Pages 249-250

  Carvalho, Rodrigo ^a   Maio, Paula ^a   Amaro, Cristina ^a   Santos, Raquel ^a   Cardoso, Jorge ^a  

^a HOSPITAL CURRY CABRAL   (Portugal)

Author keywords

Contact dermatitis; hydroxyisohexyl 3 cyclohexene carboxaldehyde; patch test

Indexed keywords

ALDEHYDE; HYDROXYISOHEXYL 3 CYCLOHEXENE CARBOXALDEHYDE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; ATOPY; AXILLA; CONTACT DERMATITIS; ECZEMA; FACE; FEMALE; HAND; HUMAN; MAJOR CLINICAL STUDY; MALE; NECK; TRUNK;

ALDEHYDES; ALLERGENS; COSMETICS; CYCLOHEXENES; DERMATITIS, ALLERGIC CONTACT; FEMALE; HUMANS; MALE; MIDDLE AGED; PATCH TESTS; PORTUGAL; PREVALENCE; RETROSPECTIVE STUDIES;

MYROXYLON BALSAMUM PEREIRAE;

EID: 80051543487     PISSN: 15569527     EISSN: 15569535     Source Type: Journal    
DOI: 10.3109/15569527.2011.554484     Document Type: Article

References (11)

1. Fenn RS. Aroma chemical usage trends in modern perfumery. Perfumer Flavorist 1989;14:1-10.
2. Frosch PJ, Johansen JD, Menné T, Rastogi SC, Bruze M, Andersen KE et al. Lyral is an important sensitizer in patients sensitive to fragrances. Br J Dermatol 1999;141:1076-1083. (Pubitemid 30046198)
3. Geier J, Brasch J, Schnuch A, Lessmann H, Pirker C, Frosch PJ; Information Network of Departments of Dermatology (IVDK) and the German Contact Dermatitis Research Group (DKG). Lyral has been included in the patch test standard series in Germany. Contact Derm 2002;46:295-297.
4. Baxter KF, Wilkinson SM, Kirk SJ. Hydroxymethyl pentylcyclohexenecarboxaldehyde (Lyral) as a fragrance allergen in the UK. Contact Derm 2003;48:117-118. (Pubitemid 36513187)
5. Bruze M, Andersen KE, Goossens A; ESCD; EECDRG. Recommendation to include fragrance mix 2 and hydroxyisohexyl 3-cyclohexene carboxaldehyde (Lyral) in the European baseline patch test series. Contact Derm 2008;58:129-133. (Pubitemid 351248573)
6. International Fragrance Associations. IFRA standards. 3 and 4-(4-Hydroxy-4-methylpentyl)-3-cyclohexene-1-carboxaldehyde (HMPCC) January 2003 (available from www.ifraorg.org). Accessed on 4 June 2008.
7. Braendstrup P, Johansen JD; Danish Contact Dermatitis Group. Hydroxyisohexyl 3-cyclohexene carboxaldehyde (Lyral) is still a frequent allergen. Contact Derm 2008;59:187-188.
8. Rietschel RL, Fowler Jr., JF. Practical aspects of patch testing. In: Rietschel RL, Fowler Jr., JF, eds. Fisher's Contact Dermatitis. 5th ed. Philadelphia: Lippincott Williams & Wilkins; 2001. pp. 9-26.
9. Belsito DV, Fowler JF Jr, Sasseville D, Marks JG Jr, De Leo VA, Storrs FJ. Delayed-type hypersensitivity to fragrance materials in a select North American population. Dermatitis 2006;17:23-28.
10. Handley J, Burrows D. Allergic contact dermatitis from the synthetic fragrances Lyral and acetyl cedrene in separate underarm deodorant preparations. Contact Derm 1994;31:288-290. (Pubitemid 24361101)
11. Hendriks SA, Bousema MT, van Ginkel CJ. Allergic contact dermatitis from the fragrance ingredient Lyral in underarm deodorant. Contact Derm 1999;41:119. (Pubitemid 29363849)