Hydroxyisohexyl 3-cyclohexene carboxaldehyde (Lyral®) is still a frequent allergen

Contact Dermatitis

Volumn 59, Issue 3, 2008, Pages 187-188

  Braendstrup, P ^a   Johansen, J D ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Epidemiology; Fragrance sensitization; Hydroxyisohexyl 3 cyclohexene carboxaldehyde; Lyral ; Restrictions

Indexed keywords

CONTACT ALLERGEN; COSMETIC; FRAGRANCE; HYDROXYISOHEXYL 3 CYCLOHEXENE CARBOXALDEHYDE; UNCLASSIFIED DRUG;

ALLERGIC REACTION; ARTICLE; CONTACT ALLERGY; CONTACT DERMATITIS; ECZEMA; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL SOCIETY; PATCH TEST; PREVALENCE; SEX DIFFERENCE; SKIN SENSITIVITY;

ALDEHYDES; ALLERGENS; CYCLOHEXENES; DENMARK; DERMATITIS, ALLERGIC CONTACT; FEMALE; HUMANS; MALE; PATCH TESTS; PERFUME; PREVALENCE;

EID: 50249181163     PISSN: 01051873     EISSN: 16000536     Source Type: Journal    
DOI: 10.1111/j.1600-0536.2008.01397.x     Document Type: Article

References (6)

1. Geier J, Brasch J, Schnuch A, Lessmann H, Pirker C, Frosch P J. Lyral has been included in the patch test standard series in Germany. Contact Dermatitis 2002 : 46 : 295 297.
2. Frosch P J, Johansen J D, Menné T et al. Lyral is an important sensitizer in patients sensitive to fragrances. Br J Dermatol 1999 : 141 : 1076 1083.
3. Baxter K F, Wilkinson S M and Kirk S J. Hydroxymethyl pentylcyclohexene-carboxaldehyde (Lyral) as a fragrance allergen in the UK. Contact Dermatitis 2003 : 48 : 117 118.
4. Bruze M, Andersen K E, Goossens A. Recommendations to include fragrance mix 2 and hydroxyisohexyl 3-cyclohexene carboxaldehyde (Lyral) in the European baseline patch test series. Contact Dermatitis 2008 : 58 : 129 133.
5. International Fragrance Associations. IFRA standards. 3 and 4-(4-Hydroxy-4-methylpentyl)-3-cyclohexene-1-carboxaldehyde (HMPCC) January 2003 (available from www.ifraorg.org) Accessed on 4 June 2008.
6. SCCNFP. Opinion of The Scientific Committee on Cosmetic Products and Non-Food Products intended for Consumers concerning hydroxyisohexyl 3-cyclohexene carboxaldehyde available from www.ec.europa.eu/health) Adopted 9 December 2003.