Cannabidiol-2′,6′-dimethyl ether as an effective protector of 15-lipoxygenase-mediated low-density lipoprotein oxidation in vitro

Biological and Pharmaceutical Bulletin

Volumn 34, Issue 8, 2011, Pages 1252-1256

  Takeda, Shuso ^a   Hirayama, Akari ^a   Urata, Shino ^a   Mano, Nobutaka ^a   Fukagawa, Keiko ^a   Imamura, Midori ^a   Irii, Ayumi ^a   Kitajima, Satomi ^a   Masuyama, Tomoko ^a   Nomiyama, Mai ^a   Tatei, Sachiko ^a   Tomita, Saari ^a   Kudo, Taichi ^a   Noguchi, Momoko ^a   Yamaguchi, Yasuhiro ^a   Okamoto, Yoshiko ^a   Amamoto, Toshiaki ^b   Fukunishi, Yoshifumi ^c   Watanabe, Kazuhito ^d   Omiecinski, Curtis John ^e   Aramaki, Hironori ^a   more..

^a DAIICHI UNIVERSITY OF PHARMACY   (Japan)

^b NEUES Corporation   (Japan)

^c NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^d HOKURIKU UNIVERSITY   (Japan)

^e PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

15 lipoxygenase; Atherosclerosis; Cannabidiol 2 ,6 dimethyl ether; Cannabinoid; Low density lipoprotein

Indexed keywords

APOLIPOPROTEIN B; ARACHIDONATE 15 LIPOXYGENASE; CANNABIDIOL 2',6' DIMETHYL ETHER; CANNABIDIOL DIMETHYL ETHER; CHOLESTERYL LINOLEIC ACID; COPPER ION; LINOLEIC ACID; OXIDIZED LOW DENSITY LIPOPROTEIN; UNCLASSIFIED DRUG; ANTIOXIDANT; CANNABIDIOL; CHOLESTEROL ESTER; CHOLESTEROL LINOLEATE; COPPER; DRUG DERIVATIVE; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ALLOSTERISM; ARTICLE; ATHEROSCLEROSIS; BINDING SITE; CATALYSIS; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; ENZYMATIC DEGRADATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME METABOLISM; IC 50; IN VITRO STUDY; LIPOPHILICITY; OXYGENATION; BIOSYNTHESIS; HUMAN; METABOLISM; OXIDATION REDUCTION REACTION;

ANTIOXIDANTS; ARACHIDONATE 15-LIPOXYGENASE; ATHEROSCLEROSIS; CANNABIDIOL; CHOLESTEROL ESTERS; CHOLESTEROL, LDL; COPPER; HUMANS; LIPOPROTEINS, LDL; OXIDATION-REDUCTION;

EID: 80051525074     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.34.1252     Document Type: Article

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