Applying the brakes to multisite SR protein phosphorylation: Substrate-induced effects on the splicing kinase SRPK1

Biochemistry

Volumn 50, Issue 32, 2011, Pages 6888-6900

  Aubol, Brandon E ^a   Adams, Joseph A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; BINDING AFFINITIES; ENZYME-SUBSTRATE COMPLEXES; EXCHANGE RATES; KINETIC EXPERIMENT; KINETIC MECHANISM; MULTI-SITE; MUTAGENESIS EXPERIMENT; N-TERMINALS; PHOSPHORYL TRANSFER; PROTEIN KINASE; PROTEIN SUBSTRATE; RAPID QUENCH; REACTION COORDINATES; SITE-SPECIFIC; SPLICING FACTORS; SR PROTEIN;

AMINO ACIDS; BINDING ENERGY; CYTOLOGY; ENZYMES; EXPERIMENTS; FRICTION MATERIALS; HYDROGEN BONDS; KINETICS; PHOSPHORYLATION; SUBSTRATES;

PROTEINS;

ADENOSINE DIPHOSPHATE; PROTEIN KINASE; PROTEIN KINASE SRPK1; SERINE ARGININE RICH PROTEIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME SUBSTRATE COMPLEX; HYDROGEN BOND; MOLECULAR DOCKING; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; RNA SPLICING;

AMINO ACID SEQUENCE; BIOCATALYSIS; HALF-LIFE; HUMANS; KINETICS; MODELS, MOLECULAR; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY; VISCOSITY;

EID: 80051521166     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi2007993     Document Type: Article

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