Enhanced sensitivity to Botulinum type A neurotoxin of human neuroblastoma SH-SY5Y cells after differentiation into mature neuronal cells

Botulinum Journal

Volumn 2, Issue 1, 2011, Pages 30-48

  Rasetti Escargueil, C ^a   MacHado, C B ^b   Preneta Blanc, R ^b   Fleck, R A ^a   Sesardic, D ^a  

^a NATIONAL INSTITUTE FOR BIOLOGICAL STANDARDS AND CONTROL   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

BoNT; Botulinum neurotoxin; Cell based assay; Differentiation; Human neuroblastoma cells; Neurotransmitter release; SH SY5Y cell line; Synaptic vesicles recycling

Indexed keywords

BOTULINUM TOXIN A; MICROTUBULE ASSOCIATED PROTEIN 2; NORADRENALIN; SYNAPTOPHYSIN; SYNAPTOSOMAL ASSOCIATED PROTEIN 25; TAU PROTEIN;

ARTICLE; CELL STRAIN SH SY5Y; CONTROLLED STUDY; EXPERIMENTAL MODEL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MEMBRANE VESICLE; NERVE CELL CULTURE; NERVE CELL DIFFERENTIATION; NERVE CELL NETWORK; NEUROBLASTOMA CELL; NEUROTOXICITY; NORADRENALIN RELEASE; PROTEIN EXPRESSION; SYNAPSE VESICLE;

EID: 80051507736     PISSN: 17547326     EISSN: 17547318     Source Type: Journal    
DOI: 10.1504/TBJ.2011.041814     Document Type: Article

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