Antioxidative constituents of the aerial parts of galium spurium

Biomolecules and Therapeutics

Volumn 19, Issue 3, 2011, Pages 336-341

  Yang, Seokwon ^a   Park, Saerom ^a   Ahn, Dalrae ^a   Yang, Jae Heon ^a   Kim, Dae Keun ^a  

^a Woosuk University   (South Korea)

Author keywords

Antioxidant activity; DPPH radical; Galium spurium l.; Rubiaceae; Superoxide quenching activity

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; ANTIOXIDANT; ASCORBIC ACID; ASPERULOSIDE; ASPERULOSIDIC ACID METHYL ESTER; BUTYLATED HYDROXYANISOLE; CAFFEIC ACID; GALIUM SPURIUM EXTRACT; ISORHAMNETIN 3 O GLUCOPYRANOSIDE; KAEMPFEROL 3 O [ALPHA LEVO RHAMNOPYRANOSYL(1-6) BETA DEXTRO GLUCOPYRANOSIDE]; KAEMPFEROL 3 O LEVO RHAMNOPYRANOSIDE; PLANT EXTRACT; PLANT MEDICINAL PRODUCT; QUERCETIN; QUERCETIN 3 O [ALPHA LEVO RHAMNOPYRANOSYL(1-6) BETA DEXTRO GLUCOPYRANOSIDE]; QUERCETIN 3 O ALPHA LEVO RHAMNOPYRANOSIDE; SCAVENGER; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ISOLATION; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; GALIUM; GALIUM SPURIUM; PHOTOCHEMICAL QUENCHING; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION;

GALIUM SPURIUM; RUBIACEAE;

EID: 79961242142     PISSN: 19769148     EISSN: 20054483     Source Type: Journal    
DOI: 10.4062/biomolther.2011.19.3.336     Document Type: Article

References (32)

1. Branen, A. L. (1975) Toxicology and biochemistry of butylated hydroxyanisole and butylated hydroxytoluene. J. Am. Oil. Chem. Soc. 52,59-63.
2. Cai, X., Yang, J. and Rao, Q. (2009) Studies on flavonoids from Galium aparine. Chin. Pharm. J. 44, 1475-1477.
3. Choi, D. S., Kim, S. J. and Jung, M. Y. (2001) Inhibitory activity of berberine on DNA strand cleavage induced by hydrogen peroxide and cytochrome c. Biosci. Biotechnol. Biochem. 65, 452-455
4. Choi, E. M. (2010) Protective effect of quercitrin against hydrogen peroxide-induced dysfunction in osteoblastic MC3T3-E1 cells. Exp. Toxicol. Pathol. in press.
5. Chung, Y. C., Chen S. J., Hsu, C. K., Chang, C. T. and Chou, S. T. (2005) Studies on the antioxidative activity of Graptopetalum para-guayense E. Walther. Food Chemistry 91, 419-424.
6. Deliorman, D., Calis, I. and Ergun, F. (2001) Iridoids from Galium aparine. Pharm. biol. 39, 234-235.
7. El-Naggar, L. J. and Beal, J. L. (1980) Iridoids. A review. J. Nat. Prod. 43, 649-706.
8. Ginnopolitis, C. N. and Ries, S. K. (1977) Superoxide dismutase. I. Occurrence in higher plants. Plant Physiol. 59, 309-314.
9. Hasan, A., Anme, K., Jay, M. and Voirin, V. (1995) Flavonoid glyco-sides and anthraquinone from Rumex chalepensis. Phytochemistry 39, 1211-1213.
10. Hong, H. K., Kwak, J. H., Kang, S. C., Lee, J. W., Park, J. H., Ahn, J. W., Kang, H. S., Choung, E. S. and Zee, O. P. (2008) Antioxidative constituents from the whole plants of Euphorbia supina. Korean J. Pharmacogn. 39, 260-264.
11. Hur, J. M., Park, J. C. and Hwang, Y. H. (2001) Aromatic acid and flavonoids from the leaves of Zanthoxylum piperitum. Nat. Prod.Sci. 7, 23-26.
12. Janbaz, K. H., Saeed, S. A. and Gilani, A. H. (2004) Studies on the protective effects of caffeic acid and quercetin on chemical-induced hepatotoxicity in rodents. Phytomedicine 5, 424-430
13. Jang, K. G., Oh, H., Ko, E. K., Kang, K. H., Park, S. E., Oh, M. H. and Kim, Y. C. (2002) Free radical scavengers from the leaves of Albizzia julibrissin. Korean J. Pharmacogn. 33, 28-30.
14. Kim, H. K., Kang, B. J., Park, K. J., Ko, B. S. and Whang, W. K. (1998) Anti-Herpes simplex virus type 1 (HSV-1) effect of isorhamnetin 3-O-β-D-glucopyranoside isolated from Brassica rapa. J. Pharm. Soc. Korea 42, 607-612.
15. Kim, S. H., Hwang, K. T. and Park, J. C. (1992) Isolation of flavonoids and determination of rutin from the leaves of Ulmus parviflora. Korean J. Pharmacogn. 23, 229-233.
16. Koyama, J., Ogura, T. and Tagahra, K. (1993) Anthraquinones of Galium spurium. Phytochemistry 33, 1540-1542.
17. Lee, H. J., Lee, S. K., Choi, Y. J., Jo, H. J., Kang, H. Y. and Choi, D. H. (2007) Extractives from the bark of Platycarya strobilacea. Journal of Korean Forest Society 96, 408-413.
18. Lee, J. H., Ku, C. H., Baek, N. I., Kim, S. H., Park, H. W. and Kim, D. K. (2004) Phytochemical constituents from Diodia teres. Arch. Pharm. Res. 27, 40-43.
19. Lee, S. K., Park, W. G. and Bae, Y. S. (1997) Procyanidins from Lindera obtusiloba bark. Mokchae konghak 25, 110-116.
20. Liu, C. M., Ma, J. Q. and Sun, Y. Z. (2010a) Quercetin protects the rat kidney against oxidative stress-mediated DNA damage and apoptosis induced by lead. Environ. Toxicol. Pharmacol. 30, 264-271.
21. Liu, C. M., Zheng, Y. L., Lu, J., Zhang, Z. F., Fan, S. H., Wu, D. M. and Ma, J. Q. (2010b) Quercetin protects rat liver against lead-induced oxidative stress and apoptosis. Environ. Toxicol. Pharmacol. 29, 158-166.
22. Monika, L. L., Zbigniew, S. and Halina, B. P. (2010) Influencn of vitamin C on markers of oxidative stress in the earliest period of ischemic stroke. Pharmacol. Rep. 62, 751-756.
23. Salvatore, R., Carmine, I., Maya, M., Nedjalka H., Simeon, P. and Mincho, A. (2000) Triterpene saponins and iridoid glucosides from Galium rivale. Phytochemistry 54, 751-756.
24. Suganya, T., Siriporn, O. and Sombat, C. (2007) Studies on antioxidative activity of certain plants in Thailand: Mechanism of antioxidant action of guava leaf extract. Food Chemistry 103, 381-388
25. Sul, D., Kim, H. S., Lee, D., Joo, S. S., Hwang, K. W. and Park, S.Y. (2009) Protective effect of caffeic acid against beta-amyloid- induced neurotoxicity by the inhibition of calcium influx and tau phosphorylation. Life Sci. 84, 257-262.
26. Takeda, Y., Shimidzu, H., Mizuno, K., Inouchi S., Masuda, T., Hirata, E., Shinzato, T., Aramoto, M. and Otsuka, H. (2002) An iridoid glucoside dimer and non-glycosidic iridoid from the leaves of Lasianthus wallichii. Chem. Pharm. Bull. 50 1395-1397.
27. Ternai, B. and Markham, K. R. (1976) Carbon-13 NMR studies of flavonoids-I: flavones and flavonols. Tetrahedron 32, 565-569.
28. Wagner, C., Fachinetto, R., Dalla, C. C. L., Brito, V. B., Severo, D.,de Oliveira, C. D. G., Morel, A. F., Nogueira, C. W. and Rocha, J.B. (2006) Quercitrin, a glycoside form of quercetin, prevents lipid peroxidation in vitro. Brain Res. 1107, 192-198.
29. Wu, Z. J., Ouyang, M. A. and Yang, C. R. (1999) Polyphenolic constituents of Salvia onchifolia. Acta Bot. Yunnan 21, 393-398.
30. Yoon, T. J., Lee, C. K., Park, T. K. and Lee, K. H. (2005) Immunostimulant and anti-tumor activity of crude extracts of Galium aparine L. Korean J. Pharmacogn. 36, 332-337.
31. Yoshida, T., Mori, K., Hatano, T., Okumura, T., Uehara, L., Komagoe, K., Fujita, Y. and Okuda, T. (1989) Studies on inhibition mechanism of autooxidation by tannins and flavonoids. V. Radical scavenging effects of tannins and related polyphenols on 1,1-diphenyl-2-picryl- hydrazyl radical. Chem. Pharm. Bull. 37, 1919-1921.
32. Zhang, L., Zhang, W. P., Chen, K. D., Qian, X. D., Fang, S. H. and Wei,E.Q. (2007) Caffeic acid attenuates neuronal damage, astrogliosis and glial scar formation in mouse brain with cryoinjury. Life Sci. 80, 530-537.