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Volumn 96, Issue 8, 2011, Pages 2540-2547

Gender, sex-steroid, and secretagogue-selective recovery from growth hormone-induced feedback in older women and men

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; GROWTH HORMONE; GROWTH HORMONE RELEASING FACTOR; GROWTH HORMONE SECRETAGOGUE; PLACEBO; PRALMORELIN; SEX HORMONE; SODIUM CHLORIDE; TESTOSTERONE;

EID: 79961229139     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2011-0298     Document Type: Article
Times cited : (11)

References (38)
  • 1
    • 0032239547 scopus 로고    scopus 로고
    • Pathophysiology of the Neuroregulation of Growth Hormone Secretion in Experimental Animals and the Human
    • Giustina A, Veldhuis JD 1998 Pathophysiology of the neuroregulation of growth hormone secretion in experimental animals and the human. Endocr Rev 19:717-797 (Pubitemid 128506521)
    • (1998) Endocrine Reviews , vol.19 , Issue.6 , pp. 717-797
    • Giustina, A.1    Veldhuis, J.D.2
  • 2
    • 33645517241 scopus 로고    scopus 로고
    • Somatotropic and gonadotropic axes linkages in infancy, childhood, and the puberty-adult transition
    • Veldhuis JD, Roemmich JN, Richmond EJ, Bowers CY 2006 Somatotropic and gonadotropic axes linkages in infancy, childhood, and the puberty-adult transition. Endocr Rev 27:101-140
    • (2006) Endocr Rev , vol.27 , pp. 101-140
    • Veldhuis, J.D.1    Roemmich, J.N.2    Richmond, E.J.3    Bowers, C.Y.4
  • 3
    • 57349192792 scopus 로고    scopus 로고
    • Motivations and methods for analyzing pulsatile hormone secretion
    • Veldhuis JD, Keenan DM, Pincus SM 2008 Motivations and methods for analyzing pulsatile hormone secretion. Endocr Rev 29:823-864
    • (2008) Endocr Rev , vol.29 , pp. 823-864
    • Veldhuis, J.D.1    Keenan, D.M.2    Pincus, S.M.3
  • 4
    • 0029786607 scopus 로고    scopus 로고
    • New insights into the regulation of somatotrope function using genetic and transgenic models
    • Frohman LA 1996 New insights into the regulation of somatotrope function using genetic and transgenic models. Metabolism 45(Suppl 1):1-3
    • (1996) Metabolism , vol.45 , Issue.SUPPL. 1 , pp. 1-3
    • Frohman, L.A.1
  • 5
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth-hormone-releasing acylated peptide from stomach
    • Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H, Kangawa K 1999 Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 402:656-660 (Pubitemid 129516334)
    • (1999) Nature , vol.402 , Issue.6762 , pp. 656-660
    • Kojima, M.1    Hosoda, H.2    Date, Y.3    Nakazato, M.4    Matsuo, H.5    Kangawa, K.6
  • 8
    • 0034974980 scopus 로고    scopus 로고
    • Growth hormone (GH) secretion in patients with an inactivating defect of the GH-releasing hormone (GHRH) receptor is pulsatile: Evidence for a role for non-GHRH inputs into the generation of GH pulses
    • DOI 10.1210/jc.86.6.2459
    • Roelfsema F, Biermasz NR, Veldman RG, Veldhuis JD, Frölich M, Stokvis-Brantsma WH, Wit JM 2001 Growth hormone (GH) secretion in patients with an inactivating defect of the GH-releasing hormone (GHRH) receptor is pulsatile: evidence for a role for non-GHRH inputs into the generation of GH pulses. J Clin Endocrinol Metab 86:2459-2464 (Pubitemid 32545692)
    • (2001) Journal of Clinical Endocrinology and Metabolism , vol.86 , Issue.6 , pp. 2459-2464
    • Roelfsema, F.1    Biermasz, N.R.2    Veldman, R.G.3    Veldhuis, J.D.4    Frolich, M.5    Henriette, S.-B.W.6    Wit, J.-M.7
  • 9
    • 0344011123 scopus 로고    scopus 로고
    • Estradiol Supplementation Enhances Submaximal Feed-Forward Drive of Growth Hormone (GH) Secretion by Recombinant Human GH-Releasing Hormone-1,44-Amide in a Putatively Somatostatin-Withdrawn Milieu
    • DOI 10.1210/jc.2003-030410
    • Veldhuis JD, Evans WS, Bowers CY 2003 Estradiol supplementation enhances submaximal feedforward drive of growth hormone (GH) secretion by recombinant human GH-releasing hormone-1,44-amide in a putatively somatostatin-withdrawn milieu. J Clin Endocrinol Metab 88:5484-5489 (Pubitemid 37452759)
    • (2003) Journal of Clinical Endocrinology and Metabolism , vol.88 , Issue.11 , pp. 5484-5489
    • Veldhuis, J.D.1    Evans, W.S.2    Bowers, C.Y.3
  • 10
    • 0035095289 scopus 로고    scopus 로고
    • Short-term estradiol supplementation augments growth hormone (GH) secretory responsiveness to dose-varying GH-releasing peptide infusions in healthy postmenopausal women
    • DOI 10.1210/jc.86.2.551
    • Anderson SM, Shah N, Evans WS, Patrie JT, Bowers CY, Veldhuis JD 2001 Short-term estradiol supplementation augments growth hormone (GH) secretory responsiveness to dose-varying GH-releasing peptide infusions in healthy postmenopausal women. J Clin Endocrinol Metab 86:551-560 (Pubitemid 32207458)
    • (2001) Journal of Clinical Endocrinology and Metabolism , vol.86 , Issue.2 , pp. 551-560
    • Anderson, S.M.1    Shah, N.2    Evans, W.S.3    Patrie, J.T.4    Bowers, C.Y.5    Veldhuis, J.D.6
  • 11
    • 0035095877 scopus 로고    scopus 로고
    • Continuous 24-hour intravenous infusion of recombinant human growth hormone (GH)-releasing hormone-(1-44)-amide augments pulsatile, entropic, and daily rhythmic GH secretion in postmenopausal women equally in the estrogen-withdrawn and estrogen-supplemented states
    • DOI 10.1210/jc.86.2.700
    • Evans WS, Anderson SM, Hull LT, Azimi PP, Bowers CY, Veldhuis JD 2001 Continuous 24-hour intravenous infusion of recombinant human growth hormone (GH)-releasing hormone-(1,44)-amide augments pulsatile, entropic, and daily rhythmic GH secretion in postmenopausal women equally in the estrogen-withdrawn and estrogen-supplemented states. J Clin Endocrinol Metab 86:700-712 (Pubitemid 32207484)
    • (2001) Journal of Clinical Endocrinology and Metabolism , vol.86 , Issue.2 , pp. 700-712
    • Evans, W.S.1    Anderson, S.M.2    Hull, L.T.3    Azimi, P.P.4    Bowers, C.Y.5    Veldhuis, J.D.6
  • 13
    • 0019740282 scopus 로고
    • Intraventrically injected growth hormone stimulates somatostatin release into rat hypophyseal portal blood
    • Chihara K, Minamitani N, Kaji H, Arimura A, Fujita T 1981 Intraventrically injected growth hormone stimulates somatostatin release into rat hypophyseal portal blood. Endocrinology 109:2279-2281
    • (1981) Endocrinology , vol.109 , pp. 2279-2281
    • Chihara, K.1    Minamitani, N.2    Kaji, H.3    Arimura, A.4    Fujita, T.5
  • 14
    • 0027195171 scopus 로고
    • Chronic growth hormone (GH) hypersecretion induces reciprocal and reversible changes in mRNA levels from hypothalamic GH-releasing hormone and somatostatin neurons in the rat
    • Bertherat J, Timsit J, Bluet-Pajot MT, Mercadier JJ, Gourdji D, Kordon C, Epelbaum J 1993 Chronic growth hormone (GH) hypersecretion induces reciprocal and reversible changes in mRNA levels from hypothalamic GH-releasing hormone and somatostatin neurons in the rat. J Clin Invest 91:1783-1791 (Pubitemid 23127385)
    • (1993) Journal of Clinical Investigation , vol.91 , Issue.4 , pp. 1783-1791
    • Bertherat, J.1    Timsit, J.2    Bluet-Pajot, M.-T.3    Mercadier, J.-J.4    Gourdji, D.5    Kordon, C.6    Epelbaum, J.7
  • 15
    • 0037372024 scopus 로고    scopus 로고
    • Interrelationship between the novel peptide ghrelin and somatostatin/growth hormone-releasing hormone in regulation of pulsatile growth hormone secretion
    • DOI 10.1210/en.2002-220852
    • Tannenbaum GS, Epelbaum J, Bowers CY 2003 Interrelationship between the novel peptide ghrelin, somatostatin and growth hormone-releasing hormone in regulation of pulsatile growth hormone secretion. Endocrinology 144:967-974 (Pubitemid 36262864)
    • (2003) Endocrinology , vol.144 , Issue.3 , pp. 967-974
    • Tannenbaum, G.S.1    Epelbaum, J.2    Bowers, C.Y.3
  • 16
    • 0013818657 scopus 로고
    • Effects of estrogen and sex difference on secretion of human growth hormone
    • Frantz AG, Rabkin MT 1965 Effects of estrogen and sex difference on secretion of human growth hormone. J Clin Endocrinol Metab 25:1470-1480
    • (1965) J Clin Endocrinol Metab , vol.25 , pp. 1470-1480
    • Frantz, A.G.1    Rabkin, M.T.2
  • 18
    • 4544236117 scopus 로고    scopus 로고
    • Dual secretagogue drive of burst-like growth hormone secretion in postmenopausal compared with premenopausal women studied under an experimental estradiol clamp
    • DOI 10.1210/jc.2004-0424
    • Erickson D, Keenan DM, Mielke K, Bradford K, Bowers CY, Miles JM, Veldhuis JD 2004 Dual secretagogue drive of burst-like growth hormone secretion in postmenopausal compared with premenopausal women studied under an experimental estradiol clamp. J Clin Endocrinol Metab 89:4746-4754 (Pubitemid 39244497)
    • (2004) Journal of Clinical Endocrinology and Metabolism , vol.89 , Issue.9 , pp. 4746-4754
    • Erickson, D.1    Keenan, D.M.2    Mielke, K.3    Bradford, K.4    Bowers, C.Y.5    Miles, J.M.6    Veldhuis, J.D.7
  • 19
    • 15944368604 scopus 로고    scopus 로고
    • Determinants of dual secretagogue drive of burst-like growth hormone secretion in premenopausal women studied under a selective estradiol clamp
    • DOI 10.1210/jc.2004-1621
    • Erickson D, Keenan DM, Farhy L, Mielke K, Bowers CY, Veldhuis JD 2005 Determinants of dual secretagogue drive of burst-like GH secretion in premenopausal women studied under a selective estradiol clamp. J Clin Endocrinol Metab 90:1741-1751 (Pubitemid 40464047)
    • (2005) Journal of Clinical Endocrinology and Metabolism , vol.90 , Issue.3 , pp. 1741-1751
    • Erickson, D.1    Keenan, D.M.2    Farhy, L.3    Mielke, K.4    Bowers, C.Y.5    Veldhuis, J.D.6
  • 22
    • 0020817177 scopus 로고
    • The appropriateness of analysis of variance and multiple-comparison procedures
    • O'Brien PC 1983 The appropriateness of analysis of variance and multiple-comparison procedures. Biometrics 39:787-794
    • (1983) Biometrics , vol.39 , pp. 787-794
    • O'Brien, P.C.1
  • 23
    • 0030004001 scopus 로고    scopus 로고
    • Anamplitude-specific divergence in the pulsatile mode of GH secretion underlies the gender difference in mean GH concentrations in men and premenopausal women
    • van den Berg G, Veldhuis JD, Frölich M, Roelfsema F 1996 Anamplitude-specific divergence in the pulsatile mode of GH secretion underlies the gender difference in mean GH concentrations in men and premenopausal women. J Clin Endocrinol Metab 81:2460-2467
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 2460-2467
    • Van Den Berg, G.1    Veldhuis, J.D.2    Frölich, M.3    Roelfsema, F.4
  • 24
    • 2442597828 scopus 로고    scopus 로고
    • Sustained Elevation of Pulsatile Growth Hormone (GH) Secretion and Insulin-Like Growth Factor I (IGF-I), IGF-Binding Protein-3 (IGFBP-3), and IGFBP-5 Concentrations during 30-Day Continuous Subcutaneous Infusion of GH-Releasing Peptide-2 in Older Men and Women
    • DOI 10.1210/jc.2003-031799
    • Bowers CY, Granda R, Mohan S, Kuipers J, Baylink D, Veldhuis JD 2004 Sustained elevation of pulsatile growth hormone (GH) secretion and insulin-like growth factor I (IGF-I), IGF-binding protein-3 (IGFBP-3), and IGFBP-5 concentrations during 30-day continuous subcutaneous infusion of GH-releasing peptide-2 in older men and women. J Clin Endocrinol Metab 89:2290-2300 (Pubitemid 38619866)
    • (2004) Journal of Clinical Endocrinology and Metabolism , vol.89 , Issue.5 , pp. 2290-2300
    • Bowers, C.Y.1    Granda, R.2    Mohan, S.3    Kuipers, J.4    Baylink, D.5    Veldhuis, J.D.6
  • 25
    • 0034457324 scopus 로고    scopus 로고
    • Oral estradiol administration modulates continuous intravenous growth hormone (GH)-releasing peptide-2-driven GH secretion in postmenopausal women
    • DOI 10.1210/jc.85.8.2649
    • Shah N, Evans WS, Bowers CY, Veldhuis JD 2000 Oral estradiol administration modulates continuous intravenous growth hormone (GH)-releasing peptide-2 driven GH secretion in postmenopausal women. J Clin Endocrinol Metab 85:2649-2659 (Pubitemid 32269131)
    • (2000) Journal of Clinical Endocrinology and Metabolism , vol.85 , Issue.8 , pp. 2649-2659
    • Shah, N.1    Evans, W.S.2    Bowers, C.Y.3    Veldhuis, J.D.4
  • 26
    • 0033304920 scopus 로고    scopus 로고
    • Tripartite neuroendocrine activation of the human growth hormone (GH) axis in women by continuous 24-hour GH-releasing peptide infusion: Pulsatile, entropic, and nyctohemeral mechanisms
    • Shah N, Evans WS, Bowers CY, Veldhuis JD 1999 Tripartite neuroendocrine activation of the human growth-hormone (GH) axis in women by continuous 24-hour GH-releasing peptide (GHRP-2) infusion: pulsatile, entropic, and nyctohemeral mechanisms. J Clin Endocrinol Metab 84:2140-2150 (Pubitemid 30647046)
    • (1999) Journal of Clinical Endocrinology and Metabolism , vol.84 , Issue.6 , pp. 2140-2150
    • Shah, N.1    Evans, W.S.2    Bowers, C.Y.3    Veldhuis, J.D.4
  • 28
    • 0028929627 scopus 로고
    • Central effects of growth hormone-releasing hexapeptide (GHRP-6) on growth hormone release are inhibited by central somatostatin action
    • Fairhall KM, Mynett A, Robinson IC 1995 Central effects of growth hormone-releasing hexapeptide (GHRP-6) on growth hormone release are inhibited by central somatostatin action. J Endocrinol 144:555-560
    • (1995) J Endocrinol , vol.144 , pp. 555-560
    • Fairhall, K.M.1    Mynett, A.2    Robinson, I.C.3
  • 31
    • 0034998144 scopus 로고    scopus 로고
    • Genomic structure and transcriptional regulation of the human growth hormone secretagogue receptor
    • DOI 10.1210/en.142.6.2649
    • Petersenn S, Rasch AC, Penshorn M, Beil FU, Schulte HM 2001 Genomic structure and transcriptional regulation of the human growth hormone secretagogue receptor. Endocrinology 142:2649-2659 (Pubitemid 32473122)
    • (2001) Endocrinology , vol.142 , Issue.6 , pp. 2649-2659
    • Petersenn, S.1    Rasch, A.C.2    Penshorn, M.3    Beil, F.U.4    Schulte, H.M.5
  • 32
    • 0028877803 scopus 로고
    • Steroid regulation of growth hormone (GH) receptor and GH-binding protein messenger ribonucleic acid in the rat
    • Gabrielsson BG, Carmignac DF, Flavell DM, Robinson ICAF 1995 Steroid regulation of growth hormone (GH) receptor and GH-binding protein messenger ribonucleic acid in the rat. Endocrinology 136:209-217
    • (1995) Endocrinology , vol.136 , pp. 209-217
    • Gabrielsson, B.G.1    Carmignac, D.F.2    Flavell, D.M.3    Robinson, I.4
  • 33
    • 0029853001 scopus 로고    scopus 로고
    • Central administration of a growth hormone (GH) receptor mRNA antisense increases GH pulsatility and decreases hypothalamic somatostatin expression in rats
    • Pellegrini E, Bluet-Pajot MT, Mounier F, Bennett P, Kordon C, Epelbaum J 1996 Central administration of a growth hormone (GH) receptor mRNA antisense increases GH pulsatility and decreases hypothalamic somatostatin expression in rats. J Neurosci 16:8140-8148 (Pubitemid 26405074)
    • (1996) Journal of Neuroscience , vol.16 , Issue.24 , pp. 8140-8148
    • Pellegrini, E.1    Bluet-Pajot, M.T.2    Mounier, F.3    Bennett, P.4    Kordon, C.5    Epelbaum, J.6
  • 34
    • 0036347990 scopus 로고    scopus 로고
    • Accelerated escape from GH autonegative feedback in midpuberty in males: Evidence for time-delimited GH-induced somatostatinergic outflow in adolescent boys
    • DOI 10.1210/jc.87.8.3837
    • Richmond E, Rogol AD, Basdemir D, Veldhuis OL, Clarke W, Bowers CY, Veldhuis JD 2002 Accelerated escape from GH autonegative feedback in midpuberty in males: evidence for time-delimited GH-induced somatostatinergic outflow in adolescent boys. J Clin Endocrinol Metab 87:3837-3844 (Pubitemid 34879536)
    • (2002) Journal of Clinical Endocrinology and Metabolism , vol.87 , Issue.8 , pp. 3837-3844
    • Richmond, E.1    Rogol, A.D.2    Basdemir, D.3    Veldhuis, O.L.4    Clarke, W.5    Bowers, C.Y.6    Veldhuis, J.D.7
  • 35
    • 62349124646 scopus 로고    scopus 로고
    • Aromatase and 5-alpha-reductase inhibition during an exogenous testosterone clamp unveils selective sex-steroid modulation of somatostatin and growth-hormone secretagogue actions in healthy older men
    • Veldhuis JD, Mielke KL, Cosma M, Soares-Welch C, Paulo R, Miles JM, Bowers CY 2009 Aromatase and 5-alpha-reductase inhibition during an exogenous testosterone clamp unveils selective sex-steroid modulation of somatostatin and growth-hormone secretagogue actions in healthy older men. J Clin Endocrinol Metab 94:973-981
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 973-981
    • Veldhuis, J.D.1    Mielke, K.L.2    Cosma, M.3    Soares-Welch, C.4    Paulo, R.5    Miles, J.M.6    Bowers, C.Y.7
  • 36
    • 0027473686 scopus 로고
    • Influence of the high-affinity growth hormone (GH)-binding protein on plasma profiles of free and bound GH and on the apparent half-life of GH. Modeling analysis and clinical applications
    • Veldhuis JD, Johnson ML, Faunt LM, Mercado M, Baumann G 1993 Influence of the high-affinity growth hormone (GH)-binding protein on plasma profiles of free and bound GH and on the apparent half-life of GH. J Clin Invest 91:629-641 (Pubitemid 23064149)
    • (1993) Journal of Clinical Investigation , vol.91 , Issue.2 , pp. 629-641
    • Veldhuis, J.D.1    Johnson, M.L.2    Faunt, L.M.3    Mercado, M.4    Baumann, G.5
  • 37
    • 0028674283 scopus 로고
    • Analysis of nonequilibrium dynamics of bound, free, and total plasma ligand concentrations over time following nonlinear secretory inputs: Evaluation of the kinetics of two or more hormones pulsed into compartments containing multiple variable-affinity binding proteins
    • Veldhuis JD, Faunt LM, Johnson ML 1994 Analysis of nonequilibrium dynamics of bound, free, and total plasma ligand concentrations over time following nonlinear secretory inputs: evaluation of the kinetics of two or more hormones pulsed into compartments containing multiple variable-affinity binding proteins. Methods Enzymol 240:349-377
    • (1994) Methods Enzymol , vol.240 , pp. 349-377
    • Veldhuis, J.D.1    Faunt, L.M.2    Johnson, M.L.3
  • 38
    • 57349179195 scopus 로고    scopus 로고
    • Estradiol supplementation in postmenopausal women attenuates suppression of pulsatile growth hormone secretion by recombinant human insulin-like growth factor type I
    • DOI 10.1210/jc.2008-1493
    • Veldhuis JD, Keenan DM, Bailey JN, Adeniji A, Miles JM, Paulo R, Cosma M, Soares-Welch C 2008 Estradiol supplementation in postmenopausal women attenuates suppression of pulsatile growth-hormone secretion by recombinant human insulin-like growth factor type I. J Clin Endocrinol Metab 93:4471-4478 (Pubitemid 352789549)
    • (2008) Journal of Clinical Endocrinology and Metabolism , vol.93 , Issue.11 , pp. 4471-4478
    • Veldhuis, J.D.1    Keenan, D.M.2    Bailey, J.N.3    Adeniji, A.4    Miles, J.M.5    Paulo, R.6    Cosma, M.7    Soares-Welch, C.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.