Distinct contributions of angiogenesis and vascular co-option during the initiation of primary microtumors and micrometastases

Carcinogenesis

Volumn 32, Issue 8, 2011, Pages 1143-1150

  Zhao, Chengjian ^a   Yang, Hanshuo ^a   Shi, Huanshan ^a   Wang, Xiaofei ^a   Chen, Xiancheng ^a   Yuan, Yike ^a   Lin, Shuo ^a,b   Wei, Yuquan ^a  

^a SICHUAN UNIVERSITY   (China)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS; ANIMAL CELL; ARTICLE; CAPILLARY BLOOD; CELL COUNT; CELL MIGRATION; CELL PROLIFERATION; CELL SIZE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNE SYSTEM; IN VITRO STUDY; IN VIVO STUDY; MICROMETASTASIS; MOUSE; NONHUMAN; PRIMARY TUMOR; PRIORITY JOURNAL; TUMOR CELL; TUMOR GROWTH; TUMOR VOLUME; VASCULARIZATION;

EID: 79961201153     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgr076     Document Type: Article

References (40)

1. Sahai,E. (2007) Illuminating the metastatic process. Nat. Rev. Cancer, 7, 737-749.
2. Stoletov,K. et al. (2008) Catch of the day: zebrafish as a human cancer model. Oncogene, 27, 4509-4520.
3. Huang,Q. et al. (1999) Noninvasive visualization of tumors in rodent dorsal skin window chambers. Nat. Biotechnol., 17, 1033-1035.
4. Li,C.Y. et al. (2000) Initial stages of tumor cell-induced angiogenesis: evaluation via skin window chambers in rodent models. J. Natl Cancer Inst., 92, 143-147.
5. Hoffman,R.M. (2005) The multiple uses of fluorescent proteins to visualize cancer in vivo. Nat. Rev. Cancer, 5, 796-806.
6. Folkman,J. (1972) Anti-angiogenesis: new concept for therapy of solid tumors. Ann. Surg., 175, 409-416.
7. Bergers,G. et al. (2002) Tumorigenesis and the angiogenic switch. Nat. Rev. Cancer, 3, 401-410.
8. Pezzella,F. et al. (1997) Non-small-cell lung carcinoma tumor growth without morphological evidence of neo-angiogenesis. Am. J. Pathol., 51, 1417-1423.
9. Holash,J. et al. (1999) New model of tumor angiogenesis: dynamic balance between vessel regression and growth mediated by angiopoietins and VEGF. Oncogene, 18, 5356-5362.
10. Holash,J. et al. (1999) Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF. Science, 284, 1994-1998.
11. Dome,B. et al. (2002) Vascularization of cutaneous melanoma involves vessel co-option and has clinical significance. J. Pathol., 197, 355-362.
12. Küsters,B. et al. (2002) Vascular endothelial growth factor-A(165) induces progression of melanoma brain metastases without induction of sprouting angiogenesis. Cancer Res., 62, 341-345.
13. Döme,B. et al. (2007) Alternative vascularization mechanisms in cancer: pathology and therapeutic implications. Am. J. Pathol., 170, 1-15.
14. Vajkoczy,P. et al. (2002) Microtumor growth initiates angiogenic sprouting with simultaneous expression of VEGF, VEGF receptor-2, and angiopoietin-2. J. Clin. Invest., 109, 777-785.
15. Amatruda,J.F. et al. (2002) Zebrafish as a cancer model system. Cancer Cell, 1, 229-231.
16. Berghmans,S. et al. (2005) Making waves in cancer research: new models in the zebrafish. Biotechniques, 39, 227-237.
17. Lieschke,G.J. et al. (2007) Animal models of human disease: zebrafish swim into view. Nat. Rev. Genet., 8, 353-367.
18. Taylor,A.M. et al. (2009) Zebrafish tumor assays: the state of transplantation. Zebrafish, 6, 339-346.
19. Lam,S.H. et al. (2006) Conservation of gene expression signatures between zebrafish and human liver tumors and tumor progression. Nat. Biotechnol., 24, 73-75.
20. Topczewska,J.M. et al. (2006) Embryonic and tumorigenic pathways converge via nodal signaling: role in melanoma aggressiveness. Nat. Med., 12, 925-932.
21. Nicoli,S. et al. (2007) Mammalian tumor xenografts induce neovascularization in zebrafish embryos. Cancer Res., 67, 2927-2931.
22. Stoletov,K. et al. (2007) High-resolution imaging of the dynamic tumor cell vascular interface in transparent zebrafish. Proc. Natl Acad. Sci. USA, 104, 17406-17411.
23. Lee,S.L. et al. (2009) Hypoxia-induced pathological angiogenesis mediates tumor cell dissemination, invasion, and metastasis in a zebrafish tumor model. Proc. Natl Acad. Sci. USA, 106, 19485-19490.
24. Lee,L.M. et al. (2005) The fate of human malignant melanoma cells transplanted into zebrafish embryos: assessment of migration and cell division in the absence of tumor formation. Dev. Dyn., 233, 1560-1570.
25. Weinstein,B.M. (2002) Vascular cell biology in vivo: a new piscine paradigm? Trends Cell Biol., 12, 439-445.
26. Sumanas,S. et al. (2006) Ets1-related protein is a key regulator of vasculogenesis in zebrafish. PLoS Biol., 4, e10.
27. Song,M. (2007) A critical role of vascular endothelial growth factor D in zebrafish embryonic vasculogenesis and angiogenesis. Biochem. Biophys. Res. Commun., 357, 924-930.
28. Yaniv,K. et al. (2006) Live imaging of lymphatic development in the zebrafish. Nat. Med., 12, 711-716.
29. Isogai,S. et al. (2001) The vascular anatomy of the developing zebrafish: an atlas of embryonic and early larval development. Dev. Biol., 230, 278-301.
30. Millauer,B. et al. (1993) High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis. Cell, 72, 835-846.
31. Goldbrunner,R.H. et al. (2000) Vascular endothelial growth factor-driven glioma growth and vascularization in an orthotopic rat model monitored by magnetic resonance imaging. Neurosurgery, 47, 921-929.
32. Ferrara,N. (1999) Molecular and biological properties of vascular endothelial growth factor. J. Mol. Med., 77, 527-543.
33. Goldbrunner,R.H. et al. (1999) Vascularization of human glioma spheroids implanted into rat cortex is conferred by two distinct mechanisms. J. Neurosci. Res., 55, 486-495.
34. Shweiki,D. et al. (1995) Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: implications for tumor angiogenesis. Proc. Natl. Acad. Sci. USA, 92, 768-772.
35. Rubenstein,J.L. et al. (2000) Anti-VEGF antibody treatment of glioblastoma prolongs survival but results in increased vascular cooption. Neoplasia, 2, 306-314.
36. Kunkel,P. et al. (2001) Inhibition of glioma angiogenesis and growth in vivo by systemic treatment with a monoclonal antibody against vascular endothelial growth factor receptor-2. Cancer Res., 61, 6624-6628.
37. Kim,E.S. et al. (2002) Potent VEGF blockade causes regression of coopted vessels in a model of neuroblastoma. Proc. Natl. Acad. Sci. USA, 99, 11399-11404.
38. Leenders,W.P. et al. (2004) Antiangiogenic therapy of cerebral melanoma metastases results in sustained tumor progression via vessel co-option. Clin. Cancer Res., 10, 6222-6230.
39. Yamauchi,K. et al. (2006) Development of real-time subcellular dynamic multicolor imaging of cancer-cell trafficking in live mice with a variable-magnification whole-mouse imaging system. Cancer Res., 66, 4208-4214.
40. Weinberg,R.A. (2007) The Biology of Cancer. Garland Science, New York, NY.