Deletion of UCP2 in iNOS deficient mice reduces the severity of the disease during experimental autoimmune encephalomyelitis

PLoS ONE

Volumn 6, Issue 8, 2011, Pages

  Aheng, Caroline ^a   Ly, Nathalie ^a   Kelly, Mairead ^b,c   Ibrahim, Saleh ^d,e   Ricquier, Daniel ^a   Alves Guerra, Marie Clotilde ^a   Miroux, Bruno ^f  

^a INSTITUT COCHIN   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c HÔPITAL NECKER ENFANTS MALADES   (France)

^d UNIVERSITY OF LÜBECK   (Germany)

^e UNIVERSITY OF ROSTOCK   (Germany)

^f PSL Research University   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; REACTIVE OXYGEN METABOLITE; GLUTATHIONE; GLUTATHIONE DISULFIDE; INDUCIBLE NITRIC OXIDE SYNTHASE; ION CHANNEL; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL UNCOUPLING PROTEIN 2; NITRIC OXIDE; NOS2 PROTEIN, MOUSE;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CHRONIC INFLAMMATION; CLINICAL ASSESSMENT; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; GENE DELETION; GENE FUNCTION; IMMUNE RESPONSE GENE; IMMUNOCOMPETENT CELL; INDUCIBLE NITRIC OXIDE SYNTHASE GENE; MACROPHAGE FUNCTION; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; SCORING SYSTEM; UNCOUPLING PROTEIN 2 GENE; ANIMAL; BRAIN; GENETICS; HOSPITALIZATION; HUMAN; IMMUNE SYSTEM; METABOLISM; MOUSE MUTANT; OXIDATION REDUCTION REACTION; PATHOLOGY; PERITONEUM MACROPHAGE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPINAL CORD;

MUS;

ANIMALS; BRAIN; CYTOKINES; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; GLUTATHIONE; GLUTATHIONE DISULFIDE; HUMANS; IMMUNE SYSTEM; ION CHANNELS; MACROPHAGES, PERITONEAL; MICE; MICE, KNOCKOUT; MITOCHONDRIAL PROTEINS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATION-REDUCTION; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEVERITY OF ILLNESS INDEX; SPINAL CORD;

EID: 79961196380     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0022841     Document Type: Article

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