Small-molecule thyrotropin receptor agonist activates naturally occurring thyrotropin-insensitive mutants and reveals their distinct cyclic adenosine monophosphate signal persistence

Thyroid

Volumn 21, Issue 8, 2011, Pages 907-912

  Allen, Michael D ^a   Neumann, Susanne ^a   Gershengorn, Marvin C ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; HORMONE RECEPTOR STIMULATING AGENT; NCGC 00161870; SERPENTINE; THYROTROPIN; THYROTROPIN RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HEK293; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG RECEPTOR BINDING; HYPOTHYROIDISM; MUTANT; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN VARIANT; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION; SUBCLINICAL HYPOTHYROIDISM; WILD TYPE;

CELL LINE; CELL MEMBRANE; CYCLIC AMP; HEK293 CELLS; HUMANS; LIGANDS; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, THYROTROPIN; SIGNAL TRANSDUCTION; THYROTROPIN;

EID: 79961179088     PISSN: 10507256     EISSN: 15579077     Source Type: Journal    
DOI: 10.1089/thy.2011.0025     Document Type: Article

References (16)

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