Oligoclonal T cell proliferation in patients with rheumatoid arthritis and their unaffected siblings

Arthritis and Rheumatism

Volumn 39, Issue 6, 1996, Pages 904-913

  Waase, Inge ^a   Kayser, Corinna ^a   Carlson, Paula J ^a   Goronzy, Jörg J ^a   Weyand, Corelia M ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; T LYMPHOCYTE RECEPTOR;

ADULT; AGED; AMINO ACID SEQUENCE; ANTIGEN RECOGNITION; ARTICLE; BETA CHAIN; CELL INFILTRATION; CELL PROLIFERATION; CELL SURVIVAL; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; LYMPHOCYTE PROLIFERATION; PRIORITY JOURNAL; PSORIATIC ARTHRITIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHEUMATOID ARTHRITIS; RISK FACTOR; SIBLING; SYNOVIAL FLUID; SYNOVIUM; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION;

ADULT; AGED; ARTHRITIS, RHEUMATOID; BASE SEQUENCE; CD4-POSITIVE T-LYMPHOCYTES; CELL DIVISION; CELL SIZE; CLONE CELLS; FAMILY; HUMANS; IMMUNITY, CELLULAR; LYMPHOCYTE ACTIVATION; MIDDLE AGED; MOLECULAR SEQUENCE DATA; PHENOTYPE; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTE SUBSETS;

EID: 0029939649     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.1780390606     Document Type: Article

References (36)

1. Harris ED Jr: Rheumatoid arthritis: pathophysiology and implications for therapy. N Engl J Med 322:1277-1289, 1990
2. Stastny P: Association of the B-cell alloantigen DRw4 with RA. N Engl J Med 298:869-871, 1978
3. Gregersen PK, Silver J, Winchester RJ: The shared epitope hypothesis: an approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis. Arthritis Rheum 30:1205-1213, 1987
4. Nepom G, Erlich TH: MHC class-II molecules and autoimmunity. Annu Rev Immunol 9:493-525, 1991
5. Weyand CM, Hicok KC, Conn D, Goronzy JJ: The influence of HLA-DRB1 genes on the disease severity in rheumatoid arthritis. Ann Intern Med 117:801-806, 1992
6. Van Boxel JA, Paget SA: Predominantly T cell infiltrate in rheumatoid synovial membranes. N Engl J Med 293:517-520, 1975
7. Kurosaka M, Ziff M: Immunoelectron microscopic study of the distribution of T cell subsets in rheumatoid synovium. J Exp Med 58:1191-1210, 1983
8. Isaacs JD, Watts RA, Hazleman BL, Hale G, Keogan MT, Cobbold SP, Waldmann H: Humanized monoclonal antibody therapy in rheumatoid arthritis. Lancet 240:748-752, 1992
9. Moreland LW, Bucy RP, Tilden A, Pratt PW, LoBuglio AF, Khazaeli M, Everson MP, Daddona P, Ghrayeb J, Kilgarriff C, Sanders ME, Koopman WJ: Use of a chimeric monoclonal anti-CD4 antibody in patients with refractory rheumatoid arthritis. Arthritis Rheum 36:307-318, 1993
10. Firestein GS, Zvaifler NJ: How important are T cells in chronic rheumatoid synovitis? Arthritis Rheum 33:768-773, 1990
11. Goronzy JJ, Bartz-Bazzanella P, Hu W, Jendro MC, Walser-Kuntz DR, Weyand CM: Dominant clonotypes in the repertoire of peripheral CD4+ T cells in rheumatoid arthritis. J Clin Invest 94:2068-2076, 1994
12. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, Healey LA, Kaplan SR, Liang MH, Luthra HS, Medsger TA Jr, Mitchell DM, Neustadt DH, Pinals RS, Schaller JG, Sharp JT, Wilder RL, Hunder GG: The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 31:315-324, 1988
13. Weyand CM, Xie C, Goronzy JJ: Homozygosity for the HLA-DRB1 allele selects for extra-articular manifestations in rheumatoid arthritis. J Clin Invest 89:2033-2039, 1992
14. Choi Y, Kotzin B, Herron L, Callahan J, Marrack P, Kappler J: Interaction of Staphylococcus aureus toxin "superantigens" with human T cells. Proc Natl Acad Sci USA 86:8941-8945, 1989
15. Goronzy JJ, Xie C, Hu W, Lundy S, Weyand CM: Restrictions in the repertoire of allospecific T cells. J Immunol 151:825-835, 1993
16. DerSimonian H, Sugita M, Glass DN, Maier A, Weinblatt ME, Reme T, Brenner MB: Clonal Vα12.1 T cell expansion in the peripheral blood of rheumatoid arthritis patients. J Exp Med 177:1623-1631, 1993
17. Posnett DN, Sinha R, Kabak S, Russo C: Clonal populations of T cells in normal elderly humans: the T cell equivalent to "benign monoclonal gammopathy". J Exp Med 179:609-618, 1994
18. + subset in normal human subjects. J Immunol 151:5762-5769, 1993
19. + T cell expansions in normal individuals and patients with rheumatoid arthritis. J Immunol 154:3538-3547, 1995
20. Davis MM, Bjorkman PJ: T-cell antigen receptor genes and T-cell recognition. Nature 334:395-401, 1988
21. Kotzin BL, Leung DY, Kappler J, Marrack P: Superantigens and their potential role in human disease. Adv Immunol 54:99-166, 1993
22. Howell MD, Diveley JP, Lundeen KA, Esty A, Winters ST, Carlo DJ, Brostoff SW: Limited T-cell receptor beta-chain heterogeneity among interleukin 2 receptor-positive synovial T cells suggests a role for superantigen in rheumatoid arthritis. Proc Natl Acad Sci U S A 88:10921-10925, 1991
23. Matis LA: The molecular basis of T cell specificity. Annu Rev Immunol 8:65-82, 1990
24. Zamvil SS, Steinman L: The T lymphocyte in experimental allergic encephalomyelitis. Annu Rev Immunol 8:579-621, 1990
25. Oksenberg JR, Panzara MA, Begovich AB, Mitchell D, Erlich HA, Murray RS, Shimonkevitz R, Sherritt M, Rothbard J, Bernard CCA, Steinman L: Selection for TCR Vβ-Dβ-Jβ gene rearrangements with specificity for a myelin basic protein peptide in brain lesions of multiple sclerosis. Nature 362:68-70, 1993
26. Moss PAH, Moots RJ, Rosenberg WMC, Roland-Jones SJ, Bodmer HC, McMichael AJ, Bell JI: Extensive conservation of a and b chains of the human T cell antigen receptor recognizing HLA-A2 and influenza A matrix peptide. Proc Natl Acad Sci USA 88:8987-8990, 1991
27. Goronzy JJ, Weyand CM: Vasculitis in rheumatoid arthritis. Curr Opin Rheumatol 6:290-294, 1994
28. Krammer PH, Behrmann I, Daniel P, Dhein J, Debatin KM: Regulation of apoptosis in the immune system. Curr Opin Immunol 6:279-289, 1994
29. Cohen JJ, Duke RC, Fadok VA, Sellins KS: Apoptosis and programmed cell death in immunity. Annu Rev Immunol 10:267-293, 1992
30. Kroemer G: The pharmacology of T cell apoptosis. Adv Immunol 58:211-296, 1995
31. Dhein J, Walczak H, Baumler C, Debatin KM, Krammer PH: Autocrine T-cell suicide mediated by APO-1/(Fas/CD95). Nature 373:438-441, 1995
32. Brunner T, Mogil RJ, LaFace D, Yoo NJ, Mahboubi A, Echeverri F, Martin SJ, Force WR, Lynch DH, Ware CF: Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas. Nature 373:441-444, 1995
33. Ju ST, Panka DJ, Cui H, Ettinger R, El-Khatib M, Sherr DH, Stanger BZ, Marshak-Rothstein A: Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation. Nature 373:444-448, 1995
34. Alderson MR, Tough TW, Davis-Smith T, Braddy S, Falk B, Schooley KA, Goodwin RG, Smith CA, Ramsdell F, Lynch DH: Fas ligand mediates activation-induced cell death in human T lymphocytes. J Exp Med 181:71-77, 1995
35. Watanabe-Fukunaga R, Brannan CI, Copeland NG, Jenkins NA, Nagata S: Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 356:314-317, 1992
36. Lynch DH, Watson ML, Alderson MR, Baum PR, Miller RE, Tough T, Gibson M, Davis-Smith T, Smith CA, Hunter K, Bhat D, Din W, Goodwin RG, Seldin MF: The mouse Fas-ligand gene is mutated in gld mice and is part of a TNF family gene cluster. Immunity 1:131-136, 1994