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Volumn 19, Issue 16, 2011, Pages 4704-4709
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Synthesis and biological evaluation of (±)-benzhydrol derivatives as potent non-nucleoside HIV-1 reverse transcriptase inhibitors
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Author keywords
Benzhydrol; Benzophenone derivatives; HIV; NNRTIs; SAR
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Indexed keywords
BENZHYDROL DERIVATIVE;
BENZOPHENONE DERIVATIVE;
GW 4511;
GW 678248;
GW 695634;
N [4 (AMINOSULFONYL) 2 METHYLPHENYL] 2 [4 CHLORO 2 (HYDROXYPHENYLMETHYL)PHENOXYL]ACETAMIDE;
N [4 (AMINOSULFONYL) 2 METHYLPHENYL] 2 [4 CHLORO 2 [HYDROXYL (1 NAPHYLPHENYL)METHYL]PHENOXYL]ACETAMIDE;
N [4 (AMINOSULFONYL) 2 METHYLPHENYL] 2 [4 CHLORO 2 [HYDROXYL (2 CHLORPHENYL)METHYL]PHENOXYL]ACETAMIDE;
N [4 (AMINOSULFONYL) 2 METHYLPHENYL] 2 [4 CHLORO 2 [HYDROXYL (2 METHYLPHENYL)METHYL]PHENOXYL]ACETAMIDE;
N [4 (AMINOSULFONYL) 2 METHYLPHENYL] 2 [4 CHLORO 2 [HYDROXYL (2 NAPHYLPHENYL)METHYL]PHENOXYL]ACETAMIDE;
N [4 (AMINOSULFONYL) 2 METHYLPHENYL] 2 [4 CHLORO 2 [HYDROXYL (2,3 DIMETHYLPHENYL)METHYL]PHENOXYL]ACETAMIDE;
N [4 (AMINOSULFONYL) 2 METHYLPHENYL] 2 [4 CHLORO 2 [HYDROXYL (2,4 DICHLOROPHENYL)METHYL]PHENOXYL]ACETAMIDE;
N [4 (AMINOSULFONYL) 2 METHYLPHENYL] 2 [4 CHLORO 2 [HYDROXYL (2,4 DIMETHYLPHENYL)METHYL]PHENOXYL]ACETAMIDE;
N [4 (AMINOSULFONYL) 2 METHYLPHENYL] 2 [4 CHLORO 2 [HYDROXYL (2,5 DICHLOROPHENYL)METHYL]PHENOXYL]ACETAMIDE;
N [4 (AMINOSULFONYL) 2 METHYLPHENYL] 2 [4 CHLORO 2 [HYDROXYL (2,5 DIMETHYLPHENYL)METHYL]PHENOXYL]ACETAMIDE;
N [4 (AMINOSULFONYL) 2 METHYLPHENYL] 2 [4 CHLORO 2 [HYDROXYL (3 CHLORO 5 BROMOPHENYL)METHYL]PHENOXYL]ACETAMIDE;
N [4 (AMINOSULFONYL) 2 METHYLPHENYL] 2 [4 CHLORO 2 [HYDROXYL (3 CHLORO 5 CYANOPHENYL)METHYL]PHENOXYL]ACETAMIDE;
N [4 (AMINOSULFONYL) 2 METHYLPHENYL] 2 [4 CHLORO 2 [HYDROXYL (3 CHLORPHENYL)METHYL]PHENOXYL]ACETAMIDE;
N [4 (AMINOSULFONYL) 2 METHYLPHENYL] 2 [4 CHLORO 2 [HYDROXYL (3 FLUOROPHENYL)METHYL]PHENOXYL]ACETAMIDE;
N [4 (AMINOSULFONYL) 2 METHYLPHENYL] 2 [4 CHLORO 2 [HYDROXYL (3 METHYLPHENYL)METHYL]PHENOXYL]ACETAMIDE;
N [4 (AMINOSULFONYL) 2 METHYLPHENYL] 2 [4 CHLORO 2 [HYDROXYL (3 NITROPHENYL)METHYL]PHENOXYL]ACETAMIDE;
N [4 (AMINOSULFONYL) 2 METHYLPHENYL] 2 [4 CHLORO 2 [HYDROXYL (3,4 DICHLOROPHENYL)METHYL]PHENOXYL]ACETAMIDE;
N [4 (AMINOSULFONYL) 2 METHYLPHENYL] 2 [4 CHLORO 2 [HYDROXYL (3,5 DICHLOROPHENYL)METHYL]PHENOXYL]ACETAMIDE;
N [4 (AMINOSULFONYL) 2 METHYLPHENYL] 2 [4 CHLORO 2 [HYDROXYL (3,5 DIMETHYLPHENYL)METHYL]PHENOXYL]ACETAMIDE;
N [4 (AMINOSULFONYL) 2 METHYLPHENYL] 2 [4 CHLORO 2 [HYDROXYL (4 METHYLPHENYL)METHYL]PHENOXYL]ACETAMIDE;
RNA DIRECTED DNA POLYMERASE INHIBITOR;
UNCLASSIFIED DRUG;
ZIDOVUDINE;
ANTIVIRAL ACTIVITY;
ARTICLE;
CHEMICAL MODIFICATION;
CONCENTRATION RESPONSE;
CONTROLLED STUDY;
CYTOTOXICITY;
DRUG SCREENING;
DRUG SELECTIVITY;
DRUG SYNTHESIS;
ENZYME INHIBITION;
HUMAN;
HUMAN CELL;
HUMAN IMMUNODEFICIENCY VIRUS 1;
MOLECULAR MODEL;
STRUCTURE ACTIVITY RELATION;
VIRUS INHIBITION;
VIRUS REPLICATION;
ANTI-HIV AGENTS;
BENZHYDRYL COMPOUNDS;
CELL LINE;
DRUG DESIGN;
DRUG EVALUATION, PRECLINICAL;
HIV REVERSE TRANSCRIPTASE;
HIV-1;
HUMANS;
MODELS, MOLECULAR;
MOLECULAR TARGETED THERAPY;
REVERSE TRANSCRIPTASE INHIBITORS;
STRUCTURE-ACTIVITY RELATIONSHIP;
SULFONAMIDES;
HUMAN IMMUNODEFICIENCY VIRUS 1;
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EID: 79961173559
PISSN: 09680896
EISSN: 14643391
Source Type: Journal
DOI: 10.1016/j.bmc.2011.07.003 Document Type: Article |
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Times cited : (8)
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References (22)
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