Probing the interaction mode in hydrophilic interaction chromatography

Journal of Chromatography A

Volumn 1218, Issue 35, 2011, Pages 5880-5891

  Dinh, Ngoc Phuoc ^a,b   Jonsson, Tobias ^b   Irgum, Knut ^a  

^a UMEÅ UNIVERSITY   (Sweden)

^b Merck SeQuant AB   (Sweden)

Author keywords

Column classification; Hydrophilic interaction chromatography; Partial least squares; Retention factors; Selectivity

Indexed keywords

ADSORPTION MECHANISM; COLUMN CLASSIFICATION; DIPOLE-DIPOLE; ELECTROLYTE CONCENTRATION; HYDROGEN BONDING INTERACTIONS; HYDROPHILIC INTERACTION; HYDROPHILIC-INTERACTION CHROMATOGRAPHY; INTERACTION MODES; INTERACTION PATTERN; MULTIPOINT; PARTIAL LEAST SQUARES; PARTICLE DIAMETERS; PHOSPHOCHOLINE; PORE DIAMETERS; RETENTION FACTORS; RETENTION MECHANISM; SEPARATION FACTORS; SHAPE-SELECTIVITY; SILANOLS; SPECIFIC INTERACTION; STATIONARY PHASIS; SULFONIC ACID; SURFACE FUNCTIONAL GROUPS;

ADSORPTION; AMIDES; CHEMICAL PROPERTIES; ELECTROSTATICS; FUNCTIONAL GROUPS; HYDROGEN; HYDROGEN BONDS; HYDROPHOBIC CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; PRINCIPAL COMPONENT ANALYSIS; WATER CONTENT;

HYDROPHILICITY;

AMIDE; AMINE; AMPHOLYTE; BETAINE DERIVATIVE; ELECTROLYTE; HYDROXYL GROUP; PHOSPHORYLCHOLINE; SILANOL; SULFOBETAINE; SULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ADSORPTION KINETICS; ARTICLE; CHEMICAL INTERACTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; DIPOLE; HYDROGEN BOND; HYDROPHILIC INTERACTION CHROMATOGRAPHY; HYDROPHILICITY; HYDROPHOBICITY; PARTICLE SIZE; PHASE SEPARATION; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; SOLUTE; STATIC ELECTRICITY; STEREOCHEMISTRY;

CHROMATOGRAPHY, LIQUID; HYDROGEN BONDING; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; IONS; LEAST-SQUARES ANALYSIS; MODELS, CHEMICAL; PARTICLE SIZE; POROSITY; PRINCIPAL COMPONENT ANALYSIS; STATIC ELECTRICITY;

EID: 79961168064     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2011.06.037     Document Type: Article

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