Complex formation and interactions between transcription factors essential for human prolactin receptor gene transcription

Molecular and Cellular Biology

Volumn 31, Issue 16, 2011, Pages 3208-3222

  Kang, Jung Hoon ^a   Tsai Morris, Chon Hwa ^a   Dufau, Maria L ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; HOMODIMER; LEUCINE ZIPPER PROTEIN; PROLACTIN RECEPTOR; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR;

ARTICLE; BIOLUMINESCENCE RESONANCE ENERGY TRANSFER; CANCER CELL; CHROMATIN IMMUNOPRECIPITATION; COMPLEX FORMATION; CONFORMATION; CONTROLLED STUDY; DNA BINDING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; ZINC FINGER MOTIF;

BINDING SITES; BREAST NEOPLASMS; CCAAT-ENHANCER-BINDING PROTEIN-BETA; CELL LINE, TUMOR; ESTRADIOL; FEMALE; HUMANS; MULTIPROTEIN COMPLEXES; PROMOTER REGIONS, GENETIC; PROTEIN MULTIMERIZATION; RECEPTORS, PROLACTIN; SP1 TRANSCRIPTION FACTOR; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION;

EID: 79961135394     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.05337-11     Document Type: Article

References (29)

1. Björnström, L., and M. Sjoberg. 2005. Mechanisms of estrogen receptor signaling: convergence of genomic and nongenomic actions on target genes. Mol. Endocrinol. 19:833-842.
2. Brayer, K. J., and D. J. Segal. 2008. Keep your fingers off my DNA: proteinprotein interactions mediated by C2H2 zinc finger domains. Cell Biochem. Biophys. 50:111-131.
3. Courey, A. J., D. A. Holtzman, S. P. Jackson, and R. Tjian. 1989. Synergistic activation by the glutamine-rich domains of human transcription factor Sp1. Cell 59:827-836.
4. Dong, J., C. H. Tsai-Morris, and M. L. Dufau. 2006. A novel estradiol/estrogen receptor alpha-dependent transcriptional mechanism controls expression of the human prolactin receptor. J. Biol. Chem. 281:18825-18836.
5. Harvey, P. W. 2005. Human relevance of rodent prolactin-induced nongenotoxic mammary carcinogenesis: prolactin involvement in human breast cancer and significance for toxicology risk assessments. J. Appl. Toxicol. 25:179-183.
6. Héroux, M., M. Hogue, S. Lemieux, and M. Bouvier. 2007. Functional calcitonin gene-related peptide receptors are formed by the asymmetric assembly of a calcitonin receptor-like receptor homo-oligomer and a monomer of receptor activity-modifying protein-1. J. Biol. Chem. 282:31610-31620.
7. Hu, Z., L. Zhuang, and M. L. Dufau. 1996. Multiple and tissue-specific promoter control of gonadal and non-gonadal prolactin receptor gene expression. J. Biol. Chem. 271:10242-10246.
8. Hu, Z. Z., J. Meng, and M. L. Dufau. 2001. Isolation and characterization of two novel forms of the human prolactin receptor generated by alternative splicing of a newly identified exon 11. J. Biol. Chem. 276:41086-41094.
9. Hu, Z. Z., L. Zhuang, and M. L. Dufau. 1998. Prolactin receptor gene diversity: structure and regulation. Trends Endocrinol. Metab. 9:94-102.
10. Hu, Z. Z., L. Zhuang, J. Meng, and M. L. Dufau. 1998. Transcriptional regulation of the generic promoter III of the rat prolactin receptor gene by C/EBPbeta and Sp1. J. Biol. Chem. 273:26225-26235.
11. Hu, Z. Z., L. Zhuang, J. Meng, M. Leondires, and M. L. Dufau. 1999. The human prolactin receptor gene structure and alternative promoter utilization: the generic promoter hPIII and a novel human promoter hP(N). J. Clin. Endocrinol. Metab. 84:1153-1156.
12. Hu, Z. Z., L. Zhuang, J. Meng, C. H. Tsai-Morris, and M. L. Dufau. 2002. Complex 5′ genomic structure of the human prolactin receptor: multiple alternative exons 1 and promoter utilization. Endocrinology 143:2139-2142.
13. Kim, K., R. Barhoumi, R. Burghardt, and S. Safe. 2005. Analysis of estrogen receptor alpha-Sp1 interactions in breast cancer cells by fluorescence resonance energy transfer. Mol. Endocrinol. 19:843-854.
14. Kushner, P. J., et al. 2000. Estrogen receptor pathways to AP-1. J. Steroid Biochem. Mol. Biol. 74:311-317.
15. Lai, J. S., and W. Herr. 1992. Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations. Proc. Natl. Acad. Sci. U. S. A. 89:6958-6962.
16. Leondires, M. P., Z. Z. Hu, J. Dong, C. H. Tsai-Morris, and M. L. Dufau. 2002. Estradiol stimulates expression of two human prolactin receptor isoforms with alternative exons-1 in T47D breast cancer cells. J. Steroid Biochem. Mol. Biol. 82:263-268.
17. Meng, J., C. H. Tsai-Morris, and M. L. Dufau. 2004. Human prolactin receptor variants in breast cancer: low ratio of short forms to the long-form human prolactin receptor associated with mammary carcinoma. Cancer Res. 64:5677-5682.
18. Paech, K., et al. 1997. Differential ligand activation of estrogen receptors ERalpha and ERbeta at AP1 sites. Science 277:1508-1510.
19. Peirce, S. K., and W. Y. Chen. 2001. Quantification of prolactin receptor mRNA in multiple human tissues and cancer cell lines by real time RT-PCR. J. Endocrinol. 171:R1-R4.
20. Pfleger, K. D., R. M. Seeber, and K. A. Eidne. 2006. Bioluminescence resonance energy transfer (BRET) for the real-time detection of protein-protein interactions. Nat. Protoc. 1:337-345.
21. Porter, W., B. Saville, D. Hoivik, and S. Safe. 1997. Functional synergy between the transcription factor Sp1 and the estrogen receptor. Mol. Endocrinol. 11:1569-1580.
22. Powell, E., and W. Xu. 2008. Intermolecular interactions identify ligandselective activity of estrogen receptor alpha/beta dimers. Proc. Natl. Acad. Sci. U. S. A. 105:19012-19017.
23. Qazi, A. M., C. H. Tsai-Morris, and M. L. Dufau. 2006. Ligand-independent homo- and heterodimerization of human prolactin receptor variants: inhibitory action of the short forms by heterodimerization. Mol. Endocrinol. 20:1912-1923.
24. Ramji, D. P., and P. Foka. 2002. CCAAT/enhancer-binding proteins: structure, function and regulation. Biochem. J. 365:561-575.
25. Ray, A., K. E. Prefontaine, and P. Ray. 1994. Down-modulation of interleukin-6 gene expression by 17 beta-estradiol in the absence of high affinity DNA binding by the estrogen receptor. J. Biol. Chem. 269:12940-12946.
26. Stein, B., and M. X. Yang. 1995. Repression of the interleukin-6 promoter by estrogen receptor is mediated by NF-kappa B and C/EBP beta. Mol. Cell. Biol. 15:4971-4979.
27. Tamrazi, A., K. E. Carlson, J. R. Daniels, K. M. Hurth, and J. A. Katzenellenbogen. 2002. Estrogen receptor dimerization: ligand binding regulates dimer affinity and dimer dissociation rate. Mol. Endocrinol. 16:2706-2719.
28. Ujházy, P., et al. 1994. Ecto-5′-nucleotidase (CD73) in multidrug-resistant cell lines generated by doxorubicin. Int. J. Cancer 59:83-93.
29. Xie, Y. L., S. A. Hassan, A. M. Qazi, C. H. Tsai-Morris, and M. L. Dufau. 2009. Intramolecular disulfide bonds of the prolactin receptor short form are required for its inhibitory action on the function of the long form of the receptor. Mol. Cell. Biol. 29:2546-2555.