Symptoms and Signs Associated with Syncope in Young People with Primary Cardiac Arrhythmias

Heart Lung and Circulation

Volumn 20, Issue 9, 2011, Pages 593-598

  MacCormick, Judith M ^a,b   Crawford, Jackie R ^a   Chung, Seo Kyung ^c   Shelling, Andrew N ^a,d   Evans, Cary Anne ^a,d   Rees, Mark I ^a,c   Smith, Warren M ^a   Crozier, Ian G ^a,e   McAlister, Hugh ^f,g   Skinner, Jon R ^a  

^a STARSHIP CHILDREN S HOSPITAL   (New Zealand)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c SWANSEA UNIVERSITY   (United Kingdom)

^d UNIVERSITY OF AUCKLAND   (New Zealand)

^e CHRISTCHURCH HOSPITAL   (New Zealand)

^f WAIKATO HOSPITAL   (New Zealand)

^g NONE

Author keywords

Arrhythmia; Brugada syndrome; Long QT syndrome; Seizure; Symptoms; Syncope

Indexed keywords

ABDOMINAL PAIN; ADOLESCENT; ADULT; ARTICLE; BODY TEMPERATURE DISORDER; BRUGADA SYNDROME; CARDIAC CHANNELOPATHY; CARDIOVERSION; CHILD; CLINICAL ARTICLE; CLINICAL FEATURE; CONFUSION; DISORIENTATION; DIZZINESS; DROWSINESS; DYSPNEA; ETHNICITY; FEMALE; GENE; GENE MUTATION; HEART ARRHYTHMIA; HEART DEATH; HEART PALPITATION; HERG GENE; HUMAN; INFANT; KCNE1 GENE; KCNE2 GENE; KCNQ1 GENE; LONG QT SYNDROME; MALE; NAUSEA; PRESCHOOL CHILD; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SCHOOL CHILD; SCN5A GENE; SEIZURE; SUDDEN DEATH; SYMPTOM; SYNCOPE; URINE INCONTINENCE; VISUAL DISORDER; WEAKNESS;

ADOLESCENT; ADULT; BRUGADA SYNDROME; CHILD; CHILD, PRESCHOOL; HUMANS; LONG QT SYNDROME; MALE; NEW ZEALAND; REGISTRIES; RETROSPECTIVE STUDIES; SYNCOPE;

EID: 79961128828     PISSN: 14439506     EISSN: 14442892     Source Type: Journal    
DOI: 10.1016/j.hlc.2011.04.036     Document Type: Article

References (28)

1. Sarasin F.P., Louis-Simonet M., Carballo D., Slama S., Rajeswaran A., Metzger J.T., et al. Prospective evaluation of patients with syncope: a population-based study. Am J Med 2001, 111(3):177-184.
2. Blanc J.J., L'Her C., Touiza A., Garo B., L'Her E., Mansourati J. Prospective evaluation and outcome of patients admitted for syncope over a 1 year period. Eur Heart J 2002, 23(May (10)):815-820.
3. Serletis A., Rose S., Sheldon A.G., Sheldon R.S. Vasovagal syncope in medical students and their first-degree relatives. Eur Heart J 2006, 27(August (16)):1965-1970.
4. Goldenberg I., Moss A.J., Peterson D.R., McNitt S., Zareba W., Andrews M.L., et al. Risk factors for aborted cardiac arrest and sudden cardiac death in children with the congenital long-QT syndrome. Circulation 2008, 117(April (17)):2184-2191.
5. Spirito P., Autore C., Rapezzi C., Bernabo P., Badagliacca R., Maron M.S., et al. Syncope and risk of sudden death in hypertrophic cardiomyopathy. Circulation 2009, 119(April (13)):1703-1710.
6. Hobbs J.B., Peterson D.R., Moss A.J., McNitt S., Zareba W., Goldenberg I., et al. Risk of aborted cardiac arrest or sudden cardiac death during adolescence in the long-QT syndrome. JAMA 2006, 296(September (10)):1249-1254.
7. Hulot J.-S., Jouven X., Empana J.-P., Frank R., Fontaine G. Natural history and risk stratification of arrhythmogenic right ventricular dysplasia/cardiomyopathy. Circulation 2004, 110(October (14)):1879-1884.
8. Dalal D., Nasir K., Bomma C., Prakasa K., Tandri H., Piccini J., et al. Arrhythmogenic right ventricular dysplasia: a United States experience. Circulation 2005, 112(December (25)):3823-3832.
9. Probst V., Denjoy I., Meregalli P.G., Amirault J.-C., Sacher F., Mansourati J., et al. Clinical aspects and prognosis of Brugada syndrome in children. Circulation 2007, 115(April (15)):2042-2048.
10. Priori S.G., Napolitano C., Gasparini M., Pappone C., Bella P.D., Giordano U., et al. Natural history of Brugada syndrome: insights for risk stratification and management. Circulation 2002, 105(March (11)):1342-1347.
11. Schwartz P.J. Idiopathic long QT syndrome: progress and questions. Am Heart J 1985, 109(February (2)):399-411.
12. Moss A.J., Zareba W., Hall W.J., Schwartz P.J., Crampton R.S., Benhorin J., et al. Effectiveness and limitations of {beta}-blocker therapy in congenital long-QT syndrome. Circulation 2000, 101(February (6)):616-623.
13. Schwartz P.J., Locati E.H., Moss A.J., Crampton R.S., Trazzi R., Ruberti U. Left cardiac sympathetic denervation in the therapy of congenital long QT syndrome. A worldwide report. Circulation 1991, 84(August (2)):503-511.
14. Schwartz P.J., Priori S.G., Cerrone M., Spazzolini C., Odero A., Napolitano C., et al. Left cardiac sympathetic denervation in the management of high-risk patients affected by the long-QT syndrome. Circulation 2004, 109(April (15)):1826-1833.
15. Zareba W., Moss A.J., Daubert J.P., Hall W.J., Robinson J.L., Andrews M. Implantable cardioverter defibrillator in high-risk long QT syndrome patients. J Cardiovasc Electrophysiol 2003, 14(4):337-341.
16. MacCormick J.M., McAlister H., Crawford J., French J.K., Crozier I., Shelling A.N., et al. Misdiagnosis of long QT syndrome as epilepsy at first presentation. Ann Emerg Med 2009, 54(1):26-32.
17. Chung S.-K., MacCormick J.M., McCulley C.H., Crawford J., Eddy C.-A., Mitchell E.A., et al. Long QT and Brugada syndrome gene mutations in New Zealand. Heart Rhythm 2007, 4(10):1306-1314.
18. Yang T.P., Chung S-KB, Zhang W.M.S., Mullins J.G.L.P., McCulley C.H.P., Crawford J.N., et al. Biophysical properties of 9 KCNQ1 mutations associated with long-QT syndrome. Circ Arrhythm Electrophysiol 2009, 2(4):417-426.
19. Ganzeboom K.S., Mairuhu G., Reitsma J.B., Linzer M., Wieling W., Van Dijk N. Lifetime cumulative incidence of syncope in the general population: a study of 549 Dutch subjects aged 35-60 years. J Cardiovasc Electrophysiol 2006, 17(11):1172-1176.
20. Ganzeboom K.S., Colman N., Reitsma J.B., Shen W.K., Wieling W. Prevalence and triggers of syncope in medical students. Am J Cardiol 2003, 91(8):1006-1008.
21. Colman N., Nahm K., Ganzeboom K.S., Shen W.K., Reitsma J., Linzer M., et al. Epidemiology of reflex syncope. Clin Auton Res 2004, 14(Suppl. 1):9-17.
22. Guidelines for the diagnosis and management of syncope (version 2009): The Task Force for the Diagnosis and Management of Syncope of the European Society of Cardiology (ESC). Eur Heart J. 2009 August:ehp298.
23. Strickberger S.A., Benson D.W., Biaggioni I., Callans D.J., Cohen M.I., Ellenbogen K.A., et al. AHA/ACCF Scientific Statement on the Evaluation of Syncope: from the American Heart Association Councils on Clinical Cardiology, Cardiovascular Nursing, Cardiovascular Disease in the Young, and Stroke, and the Quality of Care and Outcomes Research Interdisciplinary Working Group; and the American College of Cardiology Foundation: in collaboration with the Heart Rhythm Society: endorsed by the American Autonomic Society. Circulation 2006, 113(January (2)):316-327.
24. Colman N., Bakker A., Linzer M., Reitsma J.B., Wieling W., Wilde A.A.M. Value of history-taking in syncope patients: in whom to suspect long QT syndrome?. Europace 2009, 11(July (7)):937-943.
25. Oh J.H., Hanusa B.H., Kapoor W.N. Do symptoms predict cardiac arrhythmias and mortality in patients with syncope?. Arch Intern Med 1999, 159(February (4)):375-380.
26. Calkins H., Shyr Y., Frumin H., Schork A., Morady F. The value of the clinical history in the differentiation of syncope due to ventricular tachycardia, atrioventricular block, and neurocardiogenic syncope. Am J Med 1995, 98(4):365-373.
27. Schwartz P.J., Priori S.G., Spazzolini C., Moss A.J., Vincent G.M., Napolitano C., et al. Genotype-phenotype correlation in the long-QT syndrome: gene-specific triggers for life-threatening arrhythmias. Circulation 2001, 103(January (1)):89-95.
28. Ackerman M.J., Tester D.J., Porter C.J. Swimming, a gene-specific arrhythmogenic trigger for inherited long QT syndrome. Mayo Clin Proc 1999, 74(11):1088-1094.