Three spectroscopic techniques evaluated as a tool to study the effects of iodination of monoclonal antibodies, exemplified by rituximab

Journal of Pharmaceutical and Biomedical Analysis

Volumn 56, Issue 3, 2011, Pages 609-614

  Tran, Ly ^a   Baars, Joke ^b   Damen, Carola ^a   Beijnen, Jos ^a,c   Huitema, Alwin ^a  

^a SLOTERVAART HOSPITAL   (Netherlands)

^b ANTONI VAN LEEUWENHOEK HOSPITAL   (Netherlands)

^c UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Circular dichroism; Fluorescence emission spectrophotometry; Immunoreactivity; Mass spectrometry; Monoclonal antibody

Indexed keywords

MONOCLONAL ANTIBODY; RITUXIMAB;

ARTICLE; CIRCULAR DICHROISM; DRUG EFFECT; DRUG STRUCTURE; FLAME PHOTOMETRY; FLUORESCENCE SPECTROSCOPY; IMMUNOREACTIVITY; INFORMATION; IODINATION; LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; PROTEIN BINDING; QUALITY CONTROL; RADIOIODINATION;

ANTIBODIES, MONOCLONAL; ANTIBODIES, MONOCLONAL, MURINE-DERIVED; CHROMATOGRAPHY, LIQUID; CIRCULAR DICHROISM; HALOGENATION; HYDROCARBONS, IODINATED; IODINE RADIOISOTOPES; MASS SPECTROMETRY; SPECTROMETRY, FLUORESCENCE;

EID: 79961127193     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2011.05.026     Document Type: Article

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