Does the classical M1/M2 dichotomy reflect the functional phenotypes of human decidual macrophages?

Expert Review of Obstetrics and Gynecology

Volumn 6, Issue 4, 2011, Pages 377-380

  Schust, Danny J ^a   Nagamatsu, Takeshi ^a  

^a University of Missouri   (United States)

Author keywords

CD11c; decidual macrophage; microarray analysis; pregnancy

Indexed keywords

GLYCOPROTEIN P 15095;

ANTIGEN PRESENTATION; ARTICLE; CELL POLARITY; CELL POPULATION; GENE EXPRESSION PROFILING; HUMAN; LIPID METABOLISM; MACROPHAGE FUNCTION; MICROARRAY ANALYSIS; NONHUMAN; PHAGOCYTOSIS; PHENOTYPE; PROTEIN EXPRESSION;

EID: 79961098777     PISSN: 17474108     EISSN: 17474116     Source Type: Journal    
DOI: 10.1586/eog.11.34     Document Type: Article

References (18)

1. Gordon S. Alternative activation of macrophages. Nat. Rev. Immunol. 3(1), 23-35 (2003). (Pubitemid 37328697)
2. Mantovani A, Sica A, Locati M. Macrophage polarization comes of age. Immunity 23(4), 344-346 (2005). (Pubitemid 41443435)
3. Parhar RS, Yagel S, Lala PK. PGE2-mediated immunosuppression by first trimester human decidual cells blocks activation of maternal leukocytes in the decidua with potential anti-trophoblast activity. Cell Immunol. 120(1), 61-74 (1989). (Pubitemid 19113710)
4. Heikkinen JMM, Komi J, Alanen A, Lassila O. Phenotypic characterization of human decidual macrophages. Clin. Exp. Immunol. 131(3), 498-505 (2003). (Pubitemid 36324142)
5. McIntire RH, Ganacias KG, Hunt JS. Programming of human monocytes by the uteroplacental environment. Reprod. Sci. 15(5), 437-447 (2008). (Pubitemid 351832777)
6. Houser BL, Tilburgs T, Hill J, Nicotra ML, Strominger JL. Two unique human decidual macrophage populations. J. Immunol. 186(4), 2633-2642 (2011).
7. Gustafsson CMJ, Matussek A, Geffers R et al. Gene expression profiling of human decidual macrophages: evidence for immunosuppressive phenotype. PLoS One 3(4), e2078 (2008).
8. Martinez FO, Gordon S, Locati M, Mantovani A. Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression. J. Immunol. 177(10), 7303-7311 (2006). (Pubitemid 44715100)
9. Yarilina APMK, Antoniv T, Hu X, Ivashkiv LB. TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon-response genes. Nat. Immunol. 9(4), 378-387 (2008). (Pubitemid 351405107)
10. Metlay JPWPM, Agger R, Crowley MT, Lawless D, Steinman RM. The distinct leukocyte integrins of mouse spleen dendritic cells as identified with new hamster monoclonal antibodies. J. Exp. Med. 171(5), 1753-1771 (1990). (Pubitemid 20167564)
11. Kammerer U, Eggert AO, Kapp M et al. Unique appearance of proliferating antigen-presenting cells expressing DC-SIGN (CD209) in the decidua of early human pregnancy. Am. J. Pathol. 162(3), 887-896 (2003). (Pubitemid 36237496)
12. Geijtenbeek TBH, Torensma R, van Vliet SJ et al. Identification of DC-SIGN, a novel dendritic cell specific ICAM-3 receptor that supports primary immune responses. Cell 100(5), 575-585 (2000).
13. Plaks V. Uterine DCs are crucial for decidua formation during embryo implantation in mice. J. Clin. Invest. 118(12), 3954-3965 (2008).
14. Burk MR, Troeger C, Brinkhaus R, Holzgreve W, Hahn S. Severely reduced presence of tissue macrophages in the basal plate of pre-eclamptic placentae. Placenta 22(4), 309-316 (2001). (Pubitemid 32537053)
15. Scholz CTB, Santoso L, Kuhn C et al. Distribution and maturity of dendritic cells in diseases of insufficient placentation. Am. J. Reprod. Immunol. 60(3), 238-245 (2008).
16. Bombell S, McGuire W. Cytokine polymorphisms in women with recurrent pregnancy loss: meta-analysis. Aust. NZJ Obstet. Gynaecol. 48(2), 147-154 (2008). (Pubitemid 351441616)
17. LaMarca BDRM, Gilbert JS, Murphy SR, Granger JP. Inflammatory cytokines in the pathophysiology of hypertension during preeclampsia. Curr. Hypertens. Rep. 9(6), 480-485 (2007).
18. Girardi GYD, Thurman JM, Holers VM, Salmon JE. Complement activation induces dysregulation of angiogenic factors and causes fetal rejection and growth restriction. J. Exp. Med. 203(9), 2165-2175 (2006). (Pubitemid 44352237)